This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Meiering, C. D.
Right arrow Articles by Maxine L. Linial
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Meiering, C. D.
Right arrow Articles by Maxine L. Linial,

 Previous Article  |  Next Article 

Clinical Microbiology Reviews, January 2001, p. 165-176, Vol. 14, No. 1
0893-8512/01/$04.00+0   DOI: 10.1128/CMR.14.1.165-176.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Historical Perspective of Foamy Virus Epidemiology and Infection

Christopher D. Meiering1,2 and Maxine L. Linial1,2,*

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109,1 and Department of Microbiology, University of Washington, Seattle, Washington 981952

Foamy viruses (FV) are complex retroviruses which are widespread in many species. Despite being discovered over 40 years ago, FV are among the least well characterized retroviruses. The replication of these viruses is different in many interesting respects from that of all other retroviruses. Infection of natural hosts by FV leads to a lifelong persistent infection, without any evidence of pathology. A large number of studies have looked at the prevalence of primate foamy viruses in the human population. Many of these studies have suggested that FV infections are prevalent in some human populations and are associated with specific diseases. More recent data, using more rigorous criteria for the presence of viruses, have not confirmed these studies. Thus, while FV are ubiquitous in all nonhuman primates, they are only acquired as rare zoonotic infections in humans. In this communication, we briefly discuss the current status of FV research and review the history of FV epidemiology, as well as the lack of pathogenicity in natural, experimental, and zoonotic infections.

* Corresponding author. Mailing address: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109. Phone: (206) 667-4442. Fax: (206) 667-5939. E-mail: mlinial{at}fhcrc.org.

Clinical Microbiology Reviews, January 2001, p. 165-176, Vol. 14, No. 1
0893-8512/01/$04.00+0   DOI: 10.1128/CMR.14.1.165-176.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Umbach, J. L., Cullen, B. R. (2009). The role of RNAi and microRNAs in animal virus replication and antiviral immunity. Genes Dev. 23: 1151-1164 [Abstract] [Full Text]  
  • Morozov, V. A., Leendertz, F. H., Junglen, S., Boesch, C., Pauli, G., Ellerbrok, H. (2009). Frequent foamy virus infection in free-living chimpanzees of the Tai National Park (Cote d'Ivoire). J. Gen. Virol. 90: 500-506 [Abstract] [Full Text]  
  • Si, Y., Pulliam, A. C., Linka, Y., Ciccone, S., Leurs, C., Yuan, J., Eckermann, O., Fruehauf, S., Mooney, S., Hanenberg, H., Clapp, D. W. (2008). Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells. Blood 112: 4458-4465 [Abstract] [Full Text]  
  • Leendertz, F. H., Zirkel, F., Couacy-Hymann, E., Ellerbrok, H., Morozov, V. A., Pauli, G., Hedemann, C., Formenty, P., Jensen, S. A., Boesch, C., Junglen, S. (2008). Interspecies Transmission of Simian Foamy Virus in a Natural Predator-Prey System. J. Virol. 82: 7741-7744 [Abstract] [Full Text]  
  • Yap, M. W., Lindemann, D., Stanke, N., Reh, J., Westphal, D., Hanenberg, H., Ohkura, S., Stoye, J. P. (2008). Restriction of Foamy Viruses by Primate Trim5{alpha}. J. Virol. 82: 5429-5439 [Abstract] [Full Text]  
  • Voisset, C., Weiss, R. A., Griffiths, D. J. (2008). Human RNA "Rumor" Viruses: the Search for Novel Human Retroviruses in Chronic Disease. Microbiol. Mol. Biol. Rev. 72: 157-196 [Abstract] [Full Text]  
  • Lin, J., Cullen, B. R. (2007). Analysis of the Interaction of Primate Retroviruses with the Human RNA Interference Machinery. J. Virol. 81: 12218-12226 [Abstract] [Full Text]  
  • Jones-Engel, L., Steinkraus, K. A., Murray, S. M., Engel, G. A., Grant, R., Aggimarangsee, N., Lee, B. P. Y.-H., May, C., Schillaci, M. A., Somgird, C., Sutthipat, T., Vojtech, L., Zhao, J., Linial, M. L. (2007). Sensitive Assays for Simian Foamy Viruses Reveal a High Prevalence of Infection in Commensal, Free-Ranging Asian Monkeys. J. Virol. 81: 7330-7337 [Abstract] [Full Text]  
  • Murray, S. M., Picker, L. J., Axthelm, M. K., Linial, M. L. (2006). Expanded Tissue Targets for Foamy Virus Replication with Simian Immunodeficiency Virus-Induced Immunosuppression. J. Virol. 80: 663-670 [Abstract] [Full Text]  
  • Lehmann-Che, J., Giron, M.-L., Delelis, O., Lochelt, M., Bittoun, P., Tobaly-Tapiero, J., de The, H., Saib, A. (2005). Protease-Dependent Uncoating of a Complex Retrovirus. J. Virol. 79: 9244-9253 [Abstract] [Full Text]  
  • Verschoor, E. J., Langenhuijzen, S., Bontjer, I., Fagrouch, Z., Niphuis, H., Warren, K. S., Eulenberger, K., Heeney, J. L. (2004). The Phylogeography of Orangutan Foamy Viruses Supports the Theory of Ancient Repopulation of Sumatra. J. Virol. 78: 12712-12716 [Abstract] [Full Text]  
  • Switzer, W. M., Bhullar, V., Shanmugam, V., Cong, M.-e., Parekh, B., Lerche, N. W., Yee, J. L., Ely, J. J., Boneva, R., Chapman, L. E., Folks, T. M., Heneine, W. (2004). Frequent Simian Foamy Virus Infection in Persons Occupationally Exposed to Nonhuman Primates. J. Virol. 78: 2780-2789 [Abstract] [Full Text]  
  • Trobridge, G., Russell, D. W. (2004). Cell Cycle Requirements for Transduction by Foamy Virus Vectors Compared to Those of Oncovirus and Lentivirus Vectors. J. Virol. 78: 2327-2335 [Abstract] [Full Text]  
  • Schwantes, A., Truyen, U., Weikel, J., Weiss, C., Lochelt, M. (2003). Application of Chimeric Feline Foamy Virus-Based Retroviral Vectors for the Induction of Antiviral Immunity in Cats. J. Virol. 77: 7830-7842 [Abstract] [Full Text]  
  • Kido, K., Bannert, H., Gronostajski, R. M., Flugel, R. M. (2003). Bel1-mediated Transactivation of the Spumaretroviral Internal Promoter Is Repressed by Nuclear Factor I. J. Biol. Chem. 278: 11836-11842 [Abstract] [Full Text]  
  • Meiering, C. D., Linial, M. L. (2002). Reactivation of a complex retrovirus is controlled by a molecular switch and is inhibited by a viral protein. Proc. Natl. Acad. Sci. USA 99: 15130-15135 [Abstract] [Full Text]  
  • Griffiths, D. J., Voisset, C., Venables, P. J. W., Weiss, R. A. (2002). Novel Endogenous Retrovirus in Rabbits Previously Reported as Human Retrovirus 5. J. Virol. 76: 7094-7102 [Abstract] [Full Text]  
  • Lecellier, C.-H., Neves, M., Giron, M.-L., Tobaly-Tapiero, J., Saib, A. (2002). Further Characterization of Equine Foamy Virus Reveals Unusual Features among the Foamy Viruses. J. Virol. 76: 7220-7227 [Abstract] [Full Text]  
  • Lecellier, C.-H., Vermeulen, W., Bachelerie, F., Giron, M.-L., Saib, A. (2002). Intra- and Intercellular Trafficking of the Foamy Virus Auxiliary Bet Protein. J. Virol. 76: 3388-3394 [Abstract] [Full Text]  
  • Meiering, C. D., Rubio, C., May, C., Linial, M. L. (2001). Cell-Type-Specific Regulation of the Two Foamy Virus Promoters. J. Virol. 75: 6547-6557 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»