Bioterrorism: Implications for the Clinical Microbiologist

doi:10.1128/CMR.14.2.364-381.2001

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Clinical Microbiology Reviews, April 2001, p. 364-381, Vol. 14, No. 2
0893-8512/01/$04.00+0 DOI: 10.1128/CMR.14.2.364-381.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Bioterrorism: Implications for the Clinical Microbiologist

Wolfgang F. Klietmann¹^,² and Kathryn L. Ruoff¹^,²^,³^,^*

Department of Pathology¹ and Clinical Microbiology Laboratories,³ Massachusetts General Hospital, Boston, Massachusetts 02114, and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115²

The specter of bioterrorism has captured the attention of government and military officials, scientists, and the general public.Compared to other sectors of the population, clinical microbiologistsare more directly impacted by concerns about bioterrorism. Thisreview focuses on the role envisioned for clinical laboratoriesin response to a bioterrorist event. The microbiology and clinicalaspects of the biological agents thought to be the most likelytools of bioterrorists are presented. The historical backgroundof the problem of bioterrorism and an overview of current U.S.preparedness planning, with an emphasis on the roles of healthcare professionals, are alsoincluded.

^* Corresponding author. Mailing address: Microbiology, GRB526, Massachusetts General Hospital, Fruit St., Boston, MA 02114.Phone: (617) 726-3611. Fax: (617) 726-5957. E-mail: kruoff{at}partners.org,ruoff{at}helix.mgh.harvard.edu.

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