This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Butaye, P.
Right arrow Articles by Haesebrouck, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Butaye, P.
Right arrow Articles by Haesebrouck, F.

Next Article 

Clinical Microbiology Reviews, April 2003, p. 175-188, Vol. 16, No. 2
0893-8512/03/$08.00+0     DOI: 10.1128/CMR.16.2.175-188.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Antimicrobial Growth Promoters Used in Animal Feed: Effects of Less Well Known Antibiotics on Gram-Positive Bacteria

Patrick Butaye,* Luc A. Devriese, and Freddy Haesebrouck

Laboratory of Veterinary Bacteriology and Mycology, Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, University of Ghent, 9820 Merelbeke, Belgium

There are not many data available on antibiotics used solely in animals and almost exclusively for growth promotion. These products include bambermycin, avilamycin, efrotomycin, and the ionophore antibiotics (monensin, salinomycin, narasin, and lasalocid). Information is also scarce for bacitracin used only marginally in human and veterinary medicine and for streptogramin antibiotics. The mechanisms of action of and resistance mechanisms against these antibiotics are described. Special emphasis is given to the prevalence of resistance among gram-positive bacteria isolated from animals and humans. Since no susceptibility breakpoints are available for most of the antibiotics discussed, an alternative approach to the interpretation of MICs is presented. Also, some pharmacokinetic data and information on the influence of these products on the intestinal flora are presented.

* Corresponding author. Present address: VAR-CODA-CERVA, Groeselenberg 99, B1180 Brussels, Belgium. Phone: 32 (0)2 379 04 15. Fax: 32 (0)2 379 06 70. E-mail: pabut{at}var.fgov.be.

Clinical Microbiology Reviews, April 2003, p. 175-188, Vol. 16, No. 2
0893-8512/03/$08.00+0     DOI: 10.1128/CMR.16.2.175-188.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Lefebvre, B., Gattuso, M., Moisan, H., Malouin, F., Diarra, M. S. (2009). Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms. Poult. Sci. 88: 1474-1484 [Abstract] [Full Text]  
  • Casadei, G., Grilli, E., Piva, A. (2009). Pediocin A modulates intestinal microflora metabolism in swine in vitro intestinal fermentations. J ANIM SCI 87: 2020-2028 [Abstract] [Full Text]  
  • Misinzo, G., Delputte, P. L., Nauwynck, H. J. (2008). Inhibition of Endosome-Lysosome System Acidification Enhances Porcine Circovirus 2 Infection of Porcine Epithelial Cells. J. Virol. 82: 1128-1135 [Abstract] [Full Text]  
  • Cheng, T.-J. R., Sung, M.-T., Liao, H.-Y., Chang, Y.-F., Chen, C.-W., Huang, C.-Y., Chou, L.-Y., Wu, Y.-D., Chen, Y.-H., Cheng, Y.-S. E., Wong, C.-H., Ma, C., Cheng, W.-C. (2008). Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics. Proc. Natl. Acad. Sci. USA 105: 431-436 [Abstract] [Full Text]  
  • Diarra, M. S., Silversides, F. G., Diarrassouba, F., Pritchard, J., Masson, L., Brousseau, R., Bonnet, C., Delaquis, P., Bach, S., Skura, B. J., Topp, E. (2007). Impact of Feed Supplementation with Antimicrobial Agents on Growth Performance of Broiler Chickens, Clostridium perfringens and Enterococcus Counts, and Antibiotic Resistance Phenotypes and Distribution of Antimicrobial Resistance Determinants in Escherichia coli Isolates. Appl. Environ. Microbiol. 73: 6566-6576 [Abstract] [Full Text]  
  • Wang, J.-H., Janas, A. M., Olson, W. J., Wu, L. (2007). Functionally Distinct Transmission of Human Immunodeficiency Virus Type 1 Mediated by Immature and Mature Dendritic Cells. J. Virol. 81: 8933-8943 [Abstract] [Full Text]  
  • Chichlowski, M., Croom, J., McBride, B. W., Daniel, L., Davis, G., Koci, M. D. (2007). Direct-Fed Microbial PrimaLac and Salinomycin Modulate Whole-Body and Intestinal Oxygen Consumption and Intestinal Mucosal Cytokine Production in the Broiler Chick. Poult. Sci. 86: 1100-1106 [Abstract] [Full Text]  
  • Poole, T. L., McReynolds, J. L., Edrington, T. S., Byrd, J. A., Callaway, T. R., Nisbet, D. J. (2006). Effect of flavophospholipol on conjugation frequency between Escherichia coli donor and recipient pairs in vitro and in the chicken gastrointestinal tract. J Antimicrob Chemother 58: 359-366 [Abstract] [Full Text]  
  • Muro, S., Mateescu, M., Gajewski, C., Robinson, M., Muzykantov, V. R., Koval, M. (2006). Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na+/H+ exchanger proteins. Am. J. Physiol. Lung Cell. Mol. Physiol. 290: L809-L817 [Abstract] [Full Text]  
  • Bywater, R., McConville, M., Phillips, I., Shryock, T. (2005). The susceptibility to growth-promoting antibiotics of Enterococcus faecium isolates from pigs and chickens in Europe. J Antimicrob Chemother 56: 538-543 [Abstract] [Full Text]  
  • Vicca, J., Stakenborg, T., Maes, D., Butaye, P., Peeters, J., de Kruif, A., Haesebrouck, F. (2004). In Vitro Susceptibilities of Mycoplasma hyopneumoniae Field Isolates. Antimicrob. Agents Chemother. 48: 4470-4472 [Abstract] [Full Text]  
  • Bobe, G., Young, J. W., Beitz, D. C. (2004). Invited Review: Pathology, Etiology, Prevention, and Treatment of Fatty Liver in Dairy Cows. J DAIRY SCI 87: 3105-3124 [Abstract] [Full Text]  
  • Scalzo, S., Corkill, J. E., Shanks, D. J., Rowan, T. G., Delaval, J., Fleetwood, A., Murphy, M., Hart, C. A. (2004). Phenotypic and Genotypic Changes in Salmonella enterica subsp. enterica Serotype Typhimurium during Passage in Intestines of Broiler Chickens Fed on Diets That Included Ionophore Anticoccidial Supplements. J. Clin. Microbiol. 42: 3399-3405 [Abstract] [Full Text]  
  • Malhotra-Kumar, S., Wang, S., Lammens, C., Chapelle, S., Goossens, H. (2003). Bacitracin-Resistant Clone of Streptococcus pyogenes Isolated from Pharyngitis Patients in Belgium. J. Clin. Microbiol. 41: 5282-5284 [Abstract] [Full Text]  
  • Houlihan, A. J., Russell, J. B. (2003). The susceptibility of ionophore-resistant Clostridium aminophilum F to other antibiotics. J Antimicrob Chemother 52: 623-628 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»