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Clinical Microbiology Reviews, July 2003, p. 497-516, Vol. 16, No. 3
0893-8512/03/$08.00+0     DOI: 10.1128/CMR.16.3.497-516.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Mycotoxins

Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118,¹ Agricultural Research Service, Southern Regional Research Center, New Orleans, Louisiana 70124²

Mycotoxins are secondary metabolites produced by microfungi that are capable of causing disease and death in humans and other animals. Because of their pharmacological activity, some mycotoxins or mycotoxin derivatives have found use as antibiotics, growth promotants, and other kinds of drugs; still others have been implicated as chemical warfare agents. This review focuses on the most important ones associated with human and veterinary diseases, including aflatoxin, citrinin, ergot akaloids, fumonisins, ochratoxin A, patulin, trichothecenes, and zearalenone.

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