This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Livermore, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Livermore, D. M.

 Previous Article  |  Next Article 

Clinical Microbiology Reviews, Oct 1995, 557-584, Vol 8, No. 4
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

beta-Lactamases in laboratory and clinical resistance

DM Livermore
Department of Medical Microbiology, London Hospital Medical College, United Kingdom.

beta-Lactamases are the commonest single cause of bacterial resistance to beta-lactam antibiotics. Numerous chromosomal and plasmid-mediated types are known and may be classified by their sequences or phenotypic properties. The ability of a beta-lactamase to cause resistance varies with its activity, quantity, and cellular location and, for gram- negative organisms, the permeability of the producer strain. beta- Lactamases sometimes cause obvious resistance to substrate drugs in routine tests; often, however, these enzymes reduce susceptibility without causing resistance at current, pharmacologically chosen breakpoints. This review considers the ability of the prevalent beta- lactamases to cause resistance to widely used beta-lactams, whether resistance is accurately reflected in routine tests, and the extent to which the antibiogram for an organism can be used to predict the type of beta-lactamase that it produces.


This article has been cited by other articles:

  • May, T., Ito, A., Okabe, S. (2009). Induction of Multidrug Resistance Mechanism in Escherichia coli Biofilms by Interplay between Tetracycline and Ampicillin Resistance Genes. Antimicrob. Agents Chemother. 53: 4628-4639 [Abstract] [Full Text]  
  • Mataseje, L. F., Xiao, J., Kost, S., Ng, L.-K., Dore, K., Mulvey, M. R., on behalf of the Canadian Public Health Laboratory, (2009). Characterization of Canadian cefoxitin-resistant non-typhoidal Salmonella isolates, 2005-06. J Antimicrob Chemother 64: 723-730 [Abstract] [Full Text]  
  • Petrosino, J. F., Galhardo, R. S., Morales, L. D., Rosenberg, S. M. (2009). Stress-Induced {beta}-Lactam Antibiotic Resistance Mutation and Sequences of Stationary-Phase Mutations in the Escherichia coli Chromosome. J. Bacteriol. 191: 5881-5889 [Abstract] [Full Text]  
  • Xi, C., Zhang, Y., Marrs, C. F., Ye, W., Simon, C., Foxman, B., Nriagu, J. (2009). Prevalence of Antibiotic Resistance in Drinking Water Treatment and Distribution Systems. Appl. Environ. Microbiol. 75: 5714-5718 [Abstract] [Full Text]  
  • Strateva, T., Yordanov, D. (2009). Pseudomonas aeruginosa - a phenomenon of bacterial resistance. J Med Microbiol 58: 1133-1148 [Abstract] [Full Text]  
  • Dashti, A A, Jadaon, M M, Habeeb, F M (2009). Can we rely on one laboratory test in detection of extended-spectrum {beta}-lactamases among Enterobacteriaceae? An evaluation of the Vitek 2 system and comparison with four other detection methods in Kuwait. J. Clin. Pathol. 62: 739-742 [Abstract] [Full Text]  
  • Sun, S., Berg, O. G., Roth, J. R., Andersson, D. I. (2009). Contribution of Gene Amplification to Evolution of Increased Antibiotic Resistance in Salmonella typhimurium. Genetics 182: 1183-1195 [Abstract] [Full Text]  
  • Kouda, S., Ohara, M., Onodera, M., Fujiue, Y., Sasaki, M., Kohara, T., Kashiyama, S., Hayashida, S., Harino, T., Tsuji, T., Itaha, H., Gotoh, N., Matsubara, A., Usui, T., Sugai, M. (2009). Increased prevalence and clonal dissemination of multidrug-resistant Pseudomonas aeruginosa with the blaIMP-1 gene cassette in Hiroshima. J Antimicrob Chemother 64: 46-51 [Abstract] [Full Text]  
  • Gonzalez-Lopez, J. J., Coelho, A., Larrosa, M. N., Lavilla, S., Bartolome, R., Prats, G. (2009). First Detection of Plasmid-Encoded blaOXY {beta}-Lactamase. Antimicrob. Agents Chemother. 53: 3143-3146 [Abstract] [Full Text]  
  • Asgarali, A., Stubbs, K. A., Oliver, A., Vocadlo, D. J., Mark, B. L. (2009). Inactivation of the Glycoside Hydrolase NagZ Attenuates Antipseudomonal {beta}-Lactam Resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 53: 2274-2282 [Abstract] [Full Text]  
  • Bibbal, D., Dupouy, V., Prere, M. F., Toutain, P. L., Bousquet-Melou, A. (2009). Relatedness of Escherichia coli Strains with Different Susceptibility Phenotypes Isolated from Swine Feces during Ampicillin Treatment. Appl. Environ. Microbiol. 75: 2999-3006 [Abstract] [Full Text]  
  • Derbyshire, H., Kay, G., Evans, K., Vaughan, C., Kavuri, U., Winstanley, T. (2009). A simple disc diffusion method for detecting AmpC and extended-spectrum {beta}-lactamases in clinical isolates of Enterobacteriaceae. J Antimicrob Chemother 63: 497-501 [Abstract] [Full Text]  
  • White, A. R., on behalf of the BSAC Working Parties on Resistanc, (2008). The British Society for Antimicrobial Chemotherapy Resistance Surveillance Project: a successful collaborative model. J Antimicrob Chemother 62: ii3-ii14 [Abstract] [Full Text]  
  • Karami, N., Hannoun, C., Adlerberth, I., Wold, A. E. (2008). Colonization dynamics of ampicillin-resistant Escherichia coli in the infantile colonic microbiota. J Antimicrob Chemother 62: 703-708 [Abstract] [Full Text]  
  • Moya, B., Juan, C., Alberti, S., Perez, J. L., Oliver, A. (2008). Benefit of Having Multiple ampD Genes for Acquiring {beta}-Lactam Resistance without Losing Fitness and Virulence in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 52: 3694-3700 [Abstract] [Full Text]  
  • Zhang, Y., Zhou, H., Shen, X.-q., Shen, P., Yu, Y.-s., Li, L.-j. (2008). Plasmid-borne armA methylase gene, together with blaCTX-M-15 and blaTEM-1, in a Klebsiella oxytoca isolate from China. J Med Microbiol 57: 1273-1276 [Abstract] [Full Text]  
  • Bethel, C. R., Distler, A. M., Ruszczycky, M. W., Carey, M. P., Carey, P. R., Hujer, A. M., Taracila, M., Helfand, M. S., Thomson, J. M., Kalp, M., Anderson, V. E., Leonard, D. A., Hujer, K. M., Abe, T., Venkatesan, A. M., Mansour, T. S., Bonomo, R. A. (2008). Inhibition of OXA-1 {beta}-Lactamase by Penems. Antimicrob. Agents Chemother. 52: 3135-3143 [Abstract] [Full Text]  
  • Marchiaro, P., Ballerini, V., Spalding, T., Cera, G., Mussi, M. A., Moran-Barrio, J., Vila, A. J., Viale, A. M., Limansky, A. S. (2008). A convenient microbiological assay employing cell-free extracts for the rapid characterization of Gram-negative carbapenemase producers. J Antimicrob Chemother 62: 336-344 [Abstract] [Full Text]  
  • Empel, J., Baraniak, A., Literacka, E., Mrowka, A., Fiett, J., Sadowy, E., Hryniewicz, W., Gniadkowski, M., and the Beta-PL Study Group, (2008). Molecular Survey of {beta}-Lactamases Conferring Resistance to Newer {beta}-Lactams in Enterobacteriaceae Isolates from Polish Hospitals. Antimicrob. Agents Chemother. 52: 2449-2454 [Abstract] [Full Text]  
  • Lee, S.-Y., Yu, J. K., Lee, S. Y., Shin, S. H., Park, H.-I., Oh, E.-J., Park, Y.-J. (2008). Evaluation of the VITEK 2 Advanced Expert System for Reporting Piperacillin Susceptibility in Klebsiella spp.. Antimicrob. Agents Chemother. 52: 2291-2292 [Full Text]  
  • Mendonca, N., Manageiro, V., Robin, F., Salgado, M. J., Ferreira, E., Canica, M., Bonnet, R. (2008). The Lys234Arg Substitution in the Enzyme SHV-72 Is a Determinant for Resistance to Clavulanic Acid Inhibition. Antimicrob. Agents Chemother. 52: 1806-1811 [Abstract] [Full Text]  
  • (2008). Risks of extended-spectrum beta-lactamases. DTB 46: 21-24 [Abstract] [Full Text]  
  • Meziane-Cherif, D., Decre, D., Hoiby, E. A., Courvalin, P., Perichon, B. (2008). Genetic and Biochemical Characterization of CAD-1, a Chromosomally Encoded New Class A Penicillinase from Carnobacterium divergens. Antimicrob. Agents Chemother. 52: 551-556 [Abstract] [Full Text]  
  • Hocquet, D., Berthelot, P., Roussel-Delvallez, M., Favre, R., Jeannot, K., Bajolet, O., Marty, N., Grattard, F., Mariani-Kurkdjian, P., Bingen, E., Husson, M.-O., Couetdic, G., Plesiat, P. (2007). Pseudomonas aeruginosa May Accumulate Drug Resistance Mechanisms without Losing Its Ability To Cause Bloodstream Infections. Antimicrob. Agents Chemother. 51: 3531-3536 [Abstract] [Full Text]  
  • Mushtaq, S., Warner, M., Ge, Y., Kaniga, K., Livermore, D. M. (2007). In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes. J Antimicrob Chemother 60: 300-311 [Abstract] [Full Text]  
  • Stubbs, K. A., Balcewich, M., Mark, B. L., Vocadlo, D. J. (2007). Small Molecule Inhibitors of a Glycoside Hydrolase Attenuate Inducible AmpC-mediated beta-Lactam Resistance. J. Biol. Chem. 282: 21382-21391 [Abstract] [Full Text]  
  • Apfalter, P., Assadian, O., Daxbock, F., Hirschl, A. M., Rotter, M. L., Makristathis, A. (2007). Extended double disc synergy testing reveals a low prevalence of extended-spectrum {beta}-lactamases in Enterobacter spp. in Vienna, Austria. J Antimicrob Chemother 59: 854-859 [Abstract] [Full Text]  
  • Zienkiewicz, M., Kern-Zdanowicz, I., Golebiewski, M., Zylinska, J., Mieczkowski, P., Gniadkowski, M., Bardowski, J., Ceglowski, P. (2007). Mosaic Structure of p1658/97, a 125-Kilobase Plasmid Harboring an Active Amplicon with the Extended-Spectrum {beta}-Lactamase Gene blaSHV-5. Antimicrob. Agents Chemother. 51: 1164-1171 [Abstract] [Full Text]  
  • Stone, N. D., O'Hara, C. M., Williams, P. P., McGowan, J. E. Jr., Tenover, F. C. (2007). Comparison of Disk Diffusion, VITEK 2, and Broth Microdilution Antimicrobial Susceptibility Test Results for Unusual Species of Enterobacteriaceae. J. Clin. Microbiol. 45: 340-346 [Abstract] [Full Text]  
  • Schmitt, J., Jacobs, E., Schmidt, H. (2007). Molecular characterization of extended-spectrum beta-lactamases in Enterobacteriaceae from patients of two hospitals in Saxony, Germany. J Med Microbiol 56: 241-249 [Abstract] [Full Text]  
  • Pleydell, E. J., Brown, P. E., Woodward, M. J., Davies, R. H., French, N. P. (2007). Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens. Appl. Environ. Microbiol. 73: 203-210 [Abstract] [Full Text]  
  • Ahmed, A. M., Furuta, K., Shimomura, K., Kasama, Y., Shimamoto, T. (2006). Genetic characterization of multidrug resistance in Shigella spp. from Japan.. J Med Microbiol 55: 1685-1691 [Abstract] [Full Text]  
  • Alves, M. S., Dias, R. C. d. S., de Castro, A. C. D., Riley, L. W., Moreira, B. M. (2006). Identification of Clinical Isolates of Indole-Positive and Indole-Negative Klebsiella spp.. J. Clin. Microbiol. 44: 3640-3646 [Abstract] [Full Text]  
  • Jiang, X., Zhang, Z., Li, M., Zhou, D., Ruan, F., Lu, Y. (2006). Detection of Extended-Spectrum {beta}-Lactamases in Clinical Isolates of Pseudomonas aeruginosa.. Antimicrob. Agents Chemother. 50: 2990-2995 [Abstract] [Full Text]  
  • Otvos, L. Jr., de Olivier Inacio, V., Wade, J. D., Cudic, P. (2006). Prior antibacterial Peptide-mediated inhibition of protein folding in bacteria mutes resistance enzymes.. Antimicrob. Agents Chemother. 50: 3146-3149 [Abstract] [Full Text]  
  • Spanu, T., Sanguinetti, M., Tumbarello, M., D'Inzeo, T., Fiori, B., Posteraro, B., Santangelo, R., Cauda, R., Fadda, G. (2006). Evaluation of the New VITEK 2 Extended-Spectrum Beta-Lactamase (ESBL) Test for Rapid Detection of ESBL Production in Enterobacteriaceae Isolates.. J. Clin. Microbiol. 44: 3257-3262 [Abstract] [Full Text]  
  • Potz, N. A. C., Hope, R., Warner, M., Johnson, A. P., Livermore, D. M., on behalf of the London & South East ESBL Project, (2006). Prevalence and mechanisms of cephalosporin resistance in Enterobacteriaceae in London and South-East England. J Antimicrob Chemother 58: 320-326 [Abstract] [Full Text]  
  • Scheetz, M. H., Hurt, K. M., Noskin, G. A., Oliphant, C. M. (2006). Applying antimicrobial pharmacodynamics to resistant gram-negative pathogens.. Am J Health Syst Pharm 63: 1346-1360 [Abstract] [Full Text]  
  • Oteo, J., Navarro, C., Cercenado, E., Delgado-Iribarren, A., Wilhelmi, I., Orden, B., Garcia, C., Miguelanez, S., Perez-Vazquez, M., Garcia-Cobos, S., Aracil, B., Bautista, V., Campos, J. (2006). Spread of Escherichia coli Strains with High-Level Cefotaxime and Ceftazidime Resistance between the Community, Long-Term Care Facilities, and Hospital Institutions.. J. Clin. Microbiol. 44: 2359-2366 [Abstract] [Full Text]  
  • Donaldson, S. C., Straley, B. A., Hegde, N. V., Sawant, A. A., DebRoy, C., Jayarao, B. M. (2006). Molecular Epidemiology of Ceftiofur-Resistant Escherichia coli Isolates from Dairy Calves.. Appl. Environ. Microbiol. 72: 3940-3948 [Abstract] [Full Text]  
  • Jacoby, G. A., Walsh, K. E., Walker, V. J. (2006). Identification of Extended-Spectrum, AmpC, and Carbapenem- Hydrolyzing {beta}-Lactamases in Escherichia coli and Klebsiella pneumoniae by Disk Tests.. J. Clin. Microbiol. 44: 1971-1976 [Abstract] [Full Text]  
  • Juan, C., Moya, B., Perez, J. L., Oliver, A. (2006). Stepwise Upregulation of the Pseudomonas aeruginosa Chromosomal Cephalosporinase Conferring High-Level {beta}-Lactam Resistance Involves Three AmpD Homologues.. Antimicrob. Agents Chemother. 50: 1780-1787 [Abstract] [Full Text]  
  • Luzzaro, F., Mezzatesta, M., Mugnaioli, C., Perilli, M., Stefani, S., Amicosante, G., Rossolini, G. M., Toniolo, A. (2006). Trends in Production of Extended-Spectrum {beta}-Lactamases among Enterobacteria of Medical Interest: Report of the Second Italian Nationwide Survey.. J. Clin. Microbiol. 44: 1659-1664 [Abstract] [Full Text]  
  • al Naiemi, N., Schipper, K., Duim, B., Bart, A. (2006). Application of Minimal Sequence Quality Values Prevents Misidentification of the blaSHV Type in Single Bacterial Isolates Carrying Different SHV Extended-Spectrum {beta}-Lactamase Genes.. J. Clin. Microbiol. 44: 1896-1898 [Abstract] [Full Text]  
  • Hocquet, D., Nordmann, P., El Garch, F., Cabanne, L., Plesiat, P. (2006). Involvement of the MexXY-OprM Efflux System in Emergence of Cefepime Resistance in Clinical Strains of Pseudomonas aeruginosa.. Antimicrob. Agents Chemother. 50: 1347-1351 [Abstract] [Full Text]  
  • Power, P., Galleni, M., Ayala, J. A., Gutkind, G. (2006). Biochemical and Molecular Characterization of Three New Variants of AmpC {beta}-Lactamases from Morganella morganii. Antimicrob. Agents Chemother. 50: 962-967 [Abstract] [Full Text]  
  • Wang, C.-X., Mi, Z.-H. (2006). Imipenem-resistant Pseudomonas aeruginosa producing IMP-1 metallo-{beta}-lactamases and lacking the outer-membrane protein OprD.. J Med Microbiol 55: 353-354 [Full Text]  
  • Tumbarello, M., Spanu, T., Sanguinetti, M., Citton, R., Montuori, E., Leone, F., Fadda, G., Cauda, R. (2006). Bloodstream Infections Caused by Extended-Spectrum-{beta}-Lactamase-Producing Klebsiella pneumoniae: Risk Factors, Molecular Epidemiology, and Clinical Outcome. Antimicrob. Agents Chemother. 50: 498-504 [Abstract] [Full Text]  
  • D'Andrea, M. M., Nucleo, E., Luzzaro, F., Giani, T., Migliavacca, R., Vailati, F., Kroumova, V., Pagani, L., Rossolini, G. M. (2006). CMY-16, a Novel Acquired AmpC-Type {beta}-Lactamase of the CMY/LAT Lineage in Multifocal Monophyletic Isolates of Proteus mirabilis from Northern Italy. Antimicrob. Agents Chemother. 50: 618-624 [Abstract] [Full Text]  
  • Kassis-Chikhani, N., Decre, D., Gautier, V., Burghoffer, B., Saliba, F., Mathieu, D., Samuel, D., Castaing, D., Petit, J.-C., Dussaix, E., Arlet, G. (2006). First outbreak of multidrug-resistant Klebsiella pneumoniae carrying blaVIM-1 and blaSHV-5 in a French university hospital. J Antimicrob Chemother 57: 142-145 [Abstract] [Full Text]  
  • Dunne, W. M. Jr., Hardin, D. J. (2005). Use of Several Inducer and Substrate Antibiotic Combinations in a Disk Approximation Assay Format To Screen for AmpC Induction in Patient Isolates of Pseudomonas aeruginosa, Enterobacter spp., Citrobacter spp., and Serratia spp.. J. Clin. Microbiol. 43: 5945-5949 [Abstract] [Full Text]  
  • Robin, F., Delmas, J., Chanal, C., Sirot, D., Sirot, J., Bonnet, R. (2005). TEM-109 (CMT-5), a Natural Complex Mutant of TEM-1 {beta}-Lactamase Combining the Amino Acid Substitutions of TEM-6 and TEM-33 (IRT-5). Antimicrob. Agents Chemother. 49: 4443-4447 [Abstract] [Full Text]  
  • Juan, C., Macia, M. D., Gutierrez, O., Vidal, C., Perez, J. L., Oliver, A. (2005). Molecular Mechanisms of {beta}-Lactam Resistance Mediated by AmpC Hyperproduction in Pseudomonas aeruginosa Clinical Strains. Antimicrob. Agents Chemother. 49: 4733-4738 [Abstract] [Full Text]  
  • Wolter, D. J., Hanson, N. D., Lister, P. D. (2005). AmpC and OprD Are Not Involved in the Mechanism of Imipenem Hypersusceptibility among Pseudomonas aeruginosa Isolates Overexpressing the mexCD-oprJ Efflux Pump. Antimicrob. Agents Chemother. 49: 4763-4766 [Abstract] [Full Text]  
  • Hoyle, D. V., Yates, C. M., Chase-Topping, M. E., Turner, E. J., Davies, S. E., Low, J. C., Gunn, G. J., Woolhouse, M. E. J., Amyes, S. G. B. (2005). Molecular Epidemiology of Antimicrobial-Resistant Commensal Escherichia coli Strains in a Cohort of Newborn Calves. Appl. Environ. Microbiol. 71: 6680-6688 [Abstract] [Full Text]  
  • Paterson, D. L., Bonomo, R. A. (2005). Extended-Spectrum {beta}-Lactamases: a Clinical Update. Clin. Microbiol. Rev. 18: 657-686 [Abstract] [Full Text]  
  • Vedel, G. (2005). Simple method to determine {beta}-lactam resistance phenotypes in Pseudomonas aeruginosa using the disc agar diffusion test. J Antimicrob Chemother 56: 657-664 [Abstract] [Full Text]  
  • Pichardo, C., Rodriguez-Martinez, J. M., Pachon-Ibanez, M. E., Conejo, C., Ibanez-Martinez, J., Martinez-Martinez, L., Pachon, J., Pascual, A. (2005). Efficacy of Cefepime and Imipenem in Experimental Murine Pneumonia Caused by Porin-Deficient Klebsiella pneumoniae Producing CMY-2 {beta}-Lactamase. Antimicrob. Agents Chemother. 49: 3311-3316 [Abstract] [Full Text]  
  • Fevre, C., Jbel, M., Passet, V., Weill, F.-X., Grimont, P. A. D., Brisse, S. (2005). Six Groups of the OXY {beta}-Lactamase Evolved over Millions of Years in Klebsiella oxytoca. Antimicrob. Agents Chemother. 49: 3453-3462 [Abstract] [Full Text]  
  • Black, J. A., Thomson, K. S., Buynak, J. D., Pitout, J. D. D. (2005). Evaluation of {beta}-Lactamase Inhibitors in Disk Tests for Detection of Plasmid-Mediated AmpC {beta}-Lactamases in Well-Characterized Clinical Strains of Klebsiella spp.. J. Clin. Microbiol. 43: 4168-4171 [Abstract] [Full Text]  
  • Winstanley, T. G., Parsons, H. K., Horstkotte, M. A., Sobottka, I., Sturenburg, E. (2005). Phenotypic detection of {beta}-lactamase-mediated resistance to oxyimino-cephalosporins in Enterobacteriaceae: evaluation of the Mastascan Elite Expert System. J Antimicrob Chemother 56: 292-296 [Abstract] [Full Text]  
  • Gangoue-Pieboji, J., Bedenic, B., Koulla-Shiro, S., Randegger, C., Adiogo, D., Ngassam, P., Ndumbe, P., Hachler, H. (2005). Extended-Spectrum-{beta}-Lactamase-Producing Enterobacteriaceae in Yaounde, Cameroon. J. Clin. Microbiol. 43: 3273-3277 [Abstract] [Full Text]  
  • Moubareck, C., Daoud, Z., Hakime, N. I., Hamze, M., Mangeney, N., Matta, H., Mokhbat, J. E., Rohban, R., Sarkis, D. K., Doucet-Populaire, F. (2005). Countrywide Spread of Community- and Hospital-Acquired Extended-Spectrum {beta}-Lactamase (CTX-M-15)-Producing Enterobacteriaceae in Lebanon. J. Clin. Microbiol. 43: 3309-3313 [Abstract] [Full Text]  
  • Yagi, T., Wachino, J.-i., Kurokawa, H., Suzuki, S., Yamane, K., Doi, Y., Shibata, N., Kato, H., Shibayama, K., Arakawa, Y. (2005). Practical Methods Using Boronic Acid Compounds for Identification of Class C {beta}-Lactamase-Producing Klebsiella pneumoniae and Escherichia coli. J. Clin. Microbiol. 43: 2551-2558 [Abstract] [Full Text]  
  • Baraniak, A., Fiett, J., Mrowka, A., Walory, J., Hryniewicz, W., Gniadkowski, M. (2005). Evolution of TEM-Type Extended-Spectrum {beta}-Lactamases in Clinical Enterobacteriaceae Strains in Poland. Antimicrob. Agents Chemother. 49: 1872-1880 [Abstract] [Full Text]  
  • Giuliani, F., Docquier, J.-D., Riccio, M. L., Pagani, L., Rossolini, G. M. (2005). OXA-46, a New Class D {beta}-Lactamase of Narrow Substrate Specificity Encoded by a blaVIM-1-Containing Integron from a Pseudomonas aeruginosa Clinical Isolate. Antimicrob. Agents Chemother. 49: 1973-1980 [Abstract] [Full Text]  
  • Bert, F., Juvin, M., Ould-Hocine, Z., Clarebout, G., Keller, E., Lambert, N., Arlet, G. (2005). Evaluation and Updating of the Osiris Expert System for Identification of Escherichia coli {beta}-Lactam Resistance Phenotypes. J. Clin. Microbiol. 43: 1846-1850 [Abstract] [Full Text]  
  • Hidri, N., Barnaud, G., Decre, D., Cerceau, C., Lalande, V., Petit, J. C., Labia, R., Arlet, G. (2005). Resistance to ceftazidime is associated with a S220Y substitution in the omega loop of the AmpC {beta}-lactamase of a Serratia marcescens clinical isolate. J Antimicrob Chemother 55: 496-499 [Abstract] [Full Text]  
  • Ahmed, A. M, Miyoshi, S.-i., Shinoda, S., Shimamoto, T. (2005). Molecular characterization of a multidrug-resistant strain of enteroinvasive Escherichia coli O164 isolated in Japan. J Med Microbiol 54: 273-278 [Abstract] [Full Text]  
  • Munday, C. J., Boyd, D. A., Brenwald, N., Miller, M., Andrews, J. M., Wise, R., Mulvey, M. R., Hawkey, P. M. (2004). Molecular and Kinetic Comparison of the Novel Extended-Spectrum {beta}-Lactamases CTX-M-25 and CTX-M-26. Antimicrob. Agents Chemother. 48: 4829-4834 [Abstract] [Full Text]  
  • Literacka, E., Empel, J., Baraniak, A., Sadowy, E., Hryniewicz, W., Gniadkowski, M. (2004). Four Variants of the Citrobacter freundii AmpC-Type Cephalosporinases, Including Novel Enzymes CMY-14 and CMY-15, in a Proteus mirabilis Clone Widespread in Poland. Antimicrob. Agents Chemother. 48: 4136-4143 [Abstract] [Full Text]  
  • Sturenburg, E., Lang, M., Horstkotte, M. A., Laufs, R., Mack, D. (2004). Evaluation of the MicroScan ESBL plus confirmation panel for detection of extended-spectrum {beta}-lactamases in clinical isolates of oxyimino-cephalosporin-resistant Gram-negative bacteria. J Antimicrob Chemother 54: 870-875 [Abstract] [Full Text]  
  • Decre, D., Burghoffer, B., Gautier, V., Petit, J.-C., Arlet, G. (2004). Outbreak of multi-resistant Klebsiella oxytoca involving strains with extended-spectrum {beta}-lactamases and strains with extended-spectrum activity of the chromosomal {beta}-lactamase. J Antimicrob Chemother 54: 881-888 [Abstract] [Full Text]  
  • Valverde, A., Coque, T. M., Sanchez-Moreno, M. P., Rollan, A., Baquero, F., Canton, R. (2004). Dramatic Increase in Prevalence of Fecal Carriage of Extended-Spectrum {beta}-Lactamase-Producing Enterobacteriaceae during Nonoutbreak Situations in Spain. J. Clin. Microbiol. 42: 4769-4775 [Abstract] [Full Text]  
  • Munday, C. J., Whitehead, G. M., Todd, N. J., Campbell, M., Hawkey, P. M. (2004). Predominance and genetic diversity of community- and hospital-acquired CTX-M extended-spectrum {beta}-lactamases in York, UK. J Antimicrob Chemother 54: 628-633 [Abstract] [Full Text]  
  • Edelstein, M., Pimkin, M., Dmitrachenko, T., Semenov, V., Kozlova, N., Gladin, D., Baraniak, A., Stratchounski, L. (2004). Multiple Outbreaks of Nosocomial Salmonellosis in Russia and Belarus Caused by a Single Clone of Salmonella enterica Serovar Typhimurium Producing an Extended-Spectrum {beta}-Lactamase. Antimicrob. Agents Chemother. 48: 2808-2815 [Abstract] [Full Text]  
  • Pai, H., Hong, J. Y., Byeon, J.-H., Kim, Y.-K., Lee, H.-J. (2004). High Prevalence of Extended-Spectrum {beta}-Lactamase-Producing Strains among Blood Isolates of Enterobacter spp. Collected in a Tertiary Hospital during an 8-Year Period and Their Antimicrobial Susceptibility Patterns. Antimicrob. Agents Chemother. 48: 3159-3161 [Abstract] [Full Text]  
  • Gray, J. T., Hungerford, L. L., Fedorka-Cray, P. J., Headrick, M. L. (2004). Extended-Spectrum-Cephalosporin Resistance in Salmonella enterica Isolates of Animal Origin. Antimicrob. Agents Chemother. 48: 3179-3181 [Abstract] [Full Text]  
  • Grimm, V., Ezaki, S., Susa, M., Knabbe, C., Schmid, Rolf. D., Bachmann, T. T. (2004). Use of DNA Microarrays for Rapid Genotyping of TEM Beta-Lactamases That Confer Resistance. J. Clin. Microbiol. 42: 3766-3774 [Abstract] [Full Text]  
  • Haeggman, S., Lofdahl, S., Paauw, A., Verhoef, J., Brisse, S. (2004). Diversity and Evolution of the Class A Chromosomal Beta-Lactamase Gene in Klebsiella pneumoniae. Antimicrob. Agents Chemother. 48: 2400-2408 [Abstract] [Full Text]  
  • Doi, Y., Wachino, J.-i., Ishiguro, M., Kurokawa, H., Yamane, K., Shibata, N., Shibayama, K., Yokoyama, K., Kato, H., Yagi, T., Arakawa, Y. (2004). Inhibitor-Sensitive AmpC {beta}-Lactamase Variant Produced by an Escherichia coli Clinical Isolate Resistant to Oxyiminocephalosporins and Cephamycins. Antimicrob. Agents Chemother. 48: 2652-2658 [Abstract] [Full Text]  
  • Jeong, S. H., Bae, I. K., Lee, J. H., Sohn, S. G., Kang, G. H., Jeon, G. J., Kim, Y. H., Jeong, B. C., Lee, S. H. (2004). Molecular Characterization of Extended-Spectrum Beta-Lactamases Produced by Clinical Isolates of Klebsiella pneumoniae and Escherichia coli from a Korean Nationwide Survey. J. Clin. Microbiol. 42: 2902-2906 [Abstract] [Full Text]  
  • Pagani, L., Mantengoli, E., Migliavacca, R., Nucleo, E., Pollini, S., Spalla, M., Daturi, R., Romero, E., Rossolini, G. M. (2004). Multifocal Detection of Multidrug-Resistant Pseudomonas aeruginosa Producing the PER-1 Extended-Spectrum {beta}-Lactamase in Northern Italy. J. Clin. Microbiol. 42: 2523-2529 [Abstract] [Full Text]  
  • Kaye, K. S., Gold, H. S., Schwaber, M. J., Venkataraman, L., Qi, Y., De Girolami, P. C., Samore, M. H., Anderson, G., Rasheed, J. K., Tenover, F. C. (2004). Variety of {beta}-Lactamases Produced by Amoxicillin-Clavulanate-Resistant Escherichia coli Isolated in the Northeastern United States. Antimicrob. Agents Chemother. 48: 1520-1525 [Abstract] [Full Text]  
  • Potz, N. A. C., Mushtaq, S., Johnson, A. P., Henwood, C. J., Walker, R. A., Varey, E., Warner, M., James, D., Livermore, D. M. (2004). Reliability of routine disc susceptibility testing by the British Society for Antimicrobial Chemotherapy (BSAC) method. J Antimicrob Chemother 53: 729-738 [Abstract] [Full Text]  
  • Hanaki, H., Kubo, R., Nakano, T., Kurihara, M., Sunagawa, K. (2004). Characterization of HMRZ-86: a novel chromogenic cephalosporin for the detection of extended-spectrum {beta}-lactamases. J Antimicrob Chemother 53: 888-889 [Full Text]  
  • Betancor, L., Schelotto, F., Martinez, A., Pereira, M., Algorta, G., Rodriguez, M. A., Vignoli, R., Chabalgoity, J. A. (2004). Random Amplified Polymorphic DNA and Phenotyping Analysis of Salmonella enterica Serovar Enteritidis Isolates Collected from Humans and Poultry in Uruguay from 1995 to 2002. J. Clin. Microbiol. 42: 1155-1162 [Abstract] [Full Text]  
  • Tumbarello, M., Citton, R., Spanu, T., Sanguinetti, M., Romano, L., Fadda, G., Cauda, R. (2004). ESBL-producing multidrug-resistant Providencia stuartii infections in a university hospital. J Antimicrob Chemother 53: 277-282 [Abstract] [Full Text]  
  • Miranda, G., Castro, N., Leanos, B., Valenzuela, A., Garza-Ramos, U., Rojas, T., Solorzano, F., Chihu, L., Silva, J. (2004). Clonal and Horizontal Dissemination of Klebsiella pneumoniae Expressing SHV-5 Extended-Spectrum {beta}-Lactamase in a Mexican Pediatric Hospital. J. Clin. Microbiol. 42: 30-35 [Abstract] [Full Text]  
  • Schwaber, M. J., Raney, P. M., Rasheed, J. K., Biddle, J. W., Williams, P., McGowan, J. E. Jr., Tenover, F. C. (2004). Utility of NCCLS Guidelines for Identifying Extended-Spectrum {beta}-Lactamases in Non-Escherichia coli and Non-Klebsiella spp. of Enterobacteriaceae. J. Clin. Microbiol. 42: 294-298 [Abstract] [Full Text]  
  • Zeng, L., Jin, S. (2003). aph(3')-IIb, a Gene Encoding an Aminoglycoside-Modifying Enzyme, Is under the Positive Control of Surrogate Regulator HpaA. Antimicrob. Agents Chemother. 47: 3867-3876 [Abstract] [Full Text]  
  • Bell, J. M., Turnidge, J. D., Jones, R. N., the SENTRY Asia-Pacific Participants,, (2003). Prevalence of Extended-Spectrum {beta}-Lactamase-Producing Enterobacter cloacae in the Asia-Pacific Region: Results from the SENTRY Antimicrobial Surveillance Program, 1998 to 2001. Antimicrob. Agents Chemother. 47: 3989-3993 [Abstract] [Full Text]  
  • Huang, W., Beharry, Z., Zhang, Z., Palzkill, T. (2003). A broad-spectrum peptide inhibitor of {beta}-lactamase identified using phage display and peptide arrays. Protein Eng Des Sel 16: 853-860 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»