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Clinical Microbiology Reviews, Jan 1996, 1-17, Vol 9, No. 1
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Infections and antibiotic resistance in nursing homes

LE Nicolle, LJ Strausbaugh and RA Garibaldi
Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.

Infections occur frequently in nursing home residents. The most common infections are pneumonia, urinary tract infection, and skin and soft tissue infection. Aging-associated physiologic and pathologic changes, functional disability, institutionalization, and invasive devices all contribute to the high occurrence of infection. Antimicrobial agent use in nursing homes is intense and usually empiric. All of these factors contribute to the increasing frequency of antimicrobial agent-resistant organisms in nursing homes. Programs that will limit the emergence and impact of antimicrobial resistance and infections in nursing homes need to be developed.


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