This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gubler, D. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gubler, D. J.

 Previous Article  |  Next Article 

Clinical Microbiology Reviews, July 1998, p. 480-496, Vol. 11, No. 3
0893-8512/98/$00.00+0

Dengue and Dengue Hemorrhagic Fever

Duane J. Gubler*

Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, P.O. Box 2087, Fort Collins, Colorado 80522

Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue hemorrhagic fever in new geographic regions. In 1998 this mosquito-borne disease is the most important tropical infectious disease after malaria, with an estimated 100 million cases of dengue fever, 500,000 cases of dengue hemorrhagic fever, and 25,000 deaths annually. The reasons for this resurgence and emergence of dengue hemorrhagic fever in the waning years of the 20th century are complex and not fully understood, but demographic, societal, and public health infrastructure changes in the past 30 years have contributed greatly. This paper reviews the changing epidemiology of dengue and dengue hemorrhagic fever by geographic region, the natural history and transmission cycles, clinical diagnosis of both dengue fever and dengue hemorrhagic fever, serologic and virologic laboratory diagnoses, pathogenesis, surveillance, prevention, and control. A major challenge for public health officials in all tropical areas of the world is to devleop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue hemorrhagic fever.

* Mailing address: Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, P.O. Box 2087, Fort Collins, CO 80522. Phone: (970) 221-6428. Fax: (970) 221-6476. E-mail: djg2{at}cdc.gov.

Clinical Microbiology Reviews, July 1998, p. 480-496, Vol. 11, No. 3
0893-8512/98/$00.00+0


This article has been cited by other articles:

  • Thomas, S. J., Nisalak, A., Anderson, K. B., Libraty, D. H., Kalayanarooj, S., Vaughn, D. W., Putnak, R., Gibbons, R. V., Jarman, R., Endy, T. P. (2009). Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance. Am J Trop Med Hyg 81: 825-833 [Abstract] [Full Text]  
  • Souza-Neto, J. A., Sim, S., Dimopoulos, G. (2009). An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense. Proc. Natl. Acad. Sci. USA 106: 17841-17846 [Abstract] [Full Text]  
  • Tomashek, K. M., Rivera, A., Munoz-Jordan, J. L., Hunsperger, E., Santiago, L., Padro, O., Garcia, E., Sun, W. (2009). Description of a Large Island-Wide Outbreak of Dengue in Puerto Rico, 2007. Am J Trop Med Hyg 81: 467-474 [Abstract] [Full Text]  
  • Perry, S. T., Prestwood, T. R., Lada, S. M., Benedict, C. A., Shresta, S. (2009). Cardif-Mediated Signaling Controls the Initial Innate Response to Dengue Virus In Vivo. J. Virol. 83: 8276-8281 [Abstract] [Full Text]  
  • Rocha, C., Silva, S., Gordon, A., Hammond, S. N., Elizondo, D., Balmaseda, A., Harris, E. (2009). Improvement in Hospital Indicators after Changes in Dengue Case Management in Nicaragua. Am J Trop Med Hyg 81: 287-292 [Abstract] [Full Text]  
  • Chen, M.-C., Lin, C.-F., Lei, H.-Y., Lin, S.-C., Liu, H.-S., Yeh, T.-M., Anderson, R., Lin, Y.-S. (2009). Deletion of the C-Terminal Region of Dengue Virus Nonstructural Protein 1 (NS1) Abolishes Anti-NS1-Mediated Platelet Dysfunction and Bleeding Tendency. J. Immunol. 183: 1797-1803 [Abstract] [Full Text]  
  • Shu, P.-Y., Su, C.-L., Liao, T.-L., Yang, C.-F., Chang, S.-F., Lin, C.-C., Chang, M.-C., Hu, H.-C., Huang, J.-H. (2009). Molecular Characterization of Dengue Viruses Imported Into Taiwan during 2003-2007: Geographic Distribution and Genotype Shift. Am J Trop Med Hyg 80: 1039-1046 [Abstract] [Full Text]  
  • Honda, S., Saito, M., Dimaano, E. M., Morales, P. A., Alonzo, M. T. G., Suarez, L.-A. C., Koike, N., Inoue, S., Kumatori, A., Matias, R. R., Natividad, F. F., Oishi, K. (2009). Increased Phagocytosis of Platelets from Patients with Secondary Dengue Virus Infection by Human Macrophages. Am J Trop Med Hyg 80: 841-845 [Abstract] [Full Text]  
  • Reyburn, A. M., Virk, A. (2009). 22-Year-Old Woman With Fever and Jaundice After Travel to Ghana. Mayo Clin Proc. 84: 461-464 [Full Text]  
  • Yauch, L. E., Zellweger, R. M., Kotturi, M. F., Qutubuddin, A., Sidney, J., Peters, B., Prestwood, T. R., Sette, A., Shresta, S. (2009). A Protective Role for Dengue Virus-Specific CD8+ T Cells. J. Immunol. 182: 4865-4873 [Abstract] [Full Text]  
  • Matlani, M., Chakravarti, A., Rawal, A., Kashyap, B., Gurtoo, A (2009). Dengue encephalitis: an entity now common in dengue-prone regions. Trop Doct 39: 115-116 [Abstract] [Full Text]  
  • Rocha, C., Morrison, A. C., Forshey, B. M., Blair, P. J., Olson, J. G., Stancil, J. D., Sihuincha, M., Scott, T. W., Kochel, T. J. (2009). Comparison of Two Active Surveillance Programs for the Detection of Clinical Dengue Cases in Iquitos, Peru. Am J Trop Med Hyg 80: 656-660 [Abstract] [Full Text]  
  • Osman, O., Fong, M. Y., Sekaran, S. D. (2009). Genetic characterization of dengue virus type 1 isolated in Brunei in 2005-2006. J. Gen. Virol. 90: 678-686 [Abstract] [Full Text]  
  • Balsitis, S. J., Coloma, J., Castro, G., Alava, A., Flores, D., McKerrow, J. H., Beatty, P. R., Harris, E. (2009). Tropism of Dengue Virus in Mice and Humans Defined by Viral Nonstructural Protein 3-Specific Immunostaining. Am J Trop Med Hyg 80: 416-424 [Abstract] [Full Text]  
  • Qiu, L.-w., Di, B., Wen, K., Wang, X.-s., Liang, W.-h., Wang, Y.-d., Pan, Y.-x., Wang, M., Ding, Y.-q., Che, X.-y. (2009). Development of an Antigen Capture Immunoassay Based on Monoclonal Antibodies Specific for Dengue Virus Serotype 2 Nonstructural Protein 1 for Early and Rapid Identification of Dengue Virus Serotype 2 Infections. CVI 16: 88-95 [Abstract] [Full Text]  
  • Cheng, H.-J., Lin, C.-F., Lei, H.-Y., Liu, H.-S., Yeh, T.-M., Luo, Y.-H., Lin, Y.-S. (2009). Proteomic Analysis of Endothelial Cell Autoantigens Recognized by Anti-Dengue Virus Nonstructural Protein 1 Antibodies. Exp. Biol. Med. 234: 63-73 [Abstract] [Full Text]  
  • Yen, Y.-T., Chen, H.-C., Lin, Y.-D., Shieh, C.-C., Wu-Hsieh, B. A. (2008). Enhancement by Tumor Necrosis Factor Alpha of Dengue Virus-Induced Endothelial Cell Production of Reactive Nitrogen and Oxygen Species Is Key to Hemorrhage Development. J. Virol. 82: 12312-12324 [Abstract] [Full Text]  
  • Luz, P. M., Mendes, B. V. M., Codeco, C. T., Struchiner, C. J., Galvani, A. P. (2008). Time Series Analysis of Dengue Incidence in Rio de Janeiro, Brazil. Am J Trop Med Hyg 79: 933-939 [Abstract] [Full Text]  
  • Matheus, S., Meynard, J.-B., Lavergne, A., Girod, R., Moua, D., Labeau, B., Dussart, P., Lacoste, V., Deparis, X. (2008). Dengue-3 Outbreak in Paraguay: Investigations Using Capillary Blood Samples on Filter Paper. Am J Trop Med Hyg 79: 685-687 [Abstract] [Full Text]  
  • Wu, S.-J., Pal, S., Ekanayake, S., Greenwald, D., Lara, S., Raviprakash, K., Kochel, T., Porter, K., Hayes, C., Nelson, W., Callahan, J. (2008). A Dry-format Field-deployable Quantitative Reverse Transcriptase-polymerase Chain Reaction Assay for Diagnosis of Dengue Infections. Am J Trop Med Hyg 79: 505-510 [Abstract] [Full Text]  
  • Das, S., Pingle, M. R., Munoz-Jordan, J., Rundell, M. S., Rondini, S., Granger, K., Chang, G.-J. J., Kelly, E., Spier, E. G., Larone, D., Spitzer, E., Barany, F., Golightly, L. M. (2008). Detection and Serotyping of Dengue Virus in Serum Samples by Multiplex Reverse Transcriptase PCR-Ligase Detection Reaction Assay. J. Clin. Microbiol. 46: 3276-3284 [Abstract] [Full Text]  
  • Nightingale, Z. D., Patkar, C., Rothman, A. L. (2008). Viral replication and paracrine effects result in distinct, functional responses of dendritic cells following infection with dengue 2 virus. J. Leukoc. Biol. 84: 1028-1038 [Abstract] [Full Text]  
  • Bessoff, K., Delorey, M., Sun, W., Hunsperger, E. (2008). Comparison of Two Commercially Available Dengue Virus (DENV) NS1 Capture Enzyme-Linked Immunosorbent Assays Using a Single Clinical Sample for Diagnosis of Acute DENV Infection. CVI 15: 1513-1518 [Abstract] [Full Text]  
  • Etemad, B., Batra, G., Raut, R., Dahiya, S., Khanam, S., Swaminathan, S., Khanna, N. (2008). An Envelope Domain III-based Chimeric Antigen Produced in Pichia pastoris Elicits Neutralizing Antibodies Against All Four Dengue Virus Serotypes. Am J Trop Med Hyg 79: 353-363 [Abstract] [Full Text]  
  • Armien, B., Suaya, J. A., Quiroz, E., Sah, B. K., Bayard, V., Marchena, L., Campos, C., Shepard, D. S. (2008). Clinical Characteristics and National Economic Cost of the 2005 Dengue Epidemic in Panama. Am J Trop Med Hyg 79: 364-371 [Abstract] [Full Text]  
  • Rajendiran, S., Lakshamanappa, H. S., Zachariah, B., Nambiar, S. (2008). Desialylation of Plasma Proteins in Severe Dengue Infection: Possible Role of Oxidative Stress. Am J Trop Med Hyg 79: 372-377 [Abstract] [Full Text]  
  • Prestwood, T. R., Prigozhin, D. M., Sharar, K. L., Zellweger, R. M., Shresta, S. (2008). A Mouse-Passaged Dengue Virus Strain with Reduced Affinity for Heparan Sulfate Causes Severe Disease in Mice by Establishing Increased Systemic Viral Loads. J. Virol. 82: 8411-8421 [Abstract] [Full Text]  
  • Kuo, M.-C., Lu, P.-L., Chang, J.-M., Lin, M.-Y., Tsai, J.-J., Chen, Y.-H., Chang, K., Chen, H.-C., Hwang, S.-J. (2008). Impact of Renal Failure on the Outcome of Dengue Viral Infection. CJASN 3: 1350-1356 [Abstract] [Full Text]  
  • Huber, K., Ba, Y., Dia, I., Mathiot, C., Sall, A. A., Diallo, M. (2008). Aedes aegypti in Senegal: Genetic Diversity and Genetic Structure of Domestic and Sylvatic Populations. Am J Trop Med Hyg 79: 218-229 [Abstract] [Full Text]  
  • De Rivera, I. L., Parham, L., Murillo, W., Moncada, W., Vazquez, S. (2008). Humoral Immune Response of Dengue Hemorrhagic Fever Cases in Children from Tegucigalpa, Honduras. Am J Trop Med Hyg 79: 262-266 [Abstract] [Full Text]  
  • Prince, H. E., Yeh, C., Lape-Nixon, M. (2008). Development of a More Efficient Algorithm for Identifying False-Positive Reactivity Results in a Dengue Virus Immunoglobulin M Screening Assay. CVI 15: 1304-1306 [Abstract] [Full Text]  
  • Raviprakash, K., Wang, D., Ewing, D., Holman, D. H., Block, K., Woraratanadharm, J., Chen, L., Hayes, C., Dong, J. Y., Porter, K. (2008). A Tetravalent Dengue Vaccine Based on a Complex Adenovirus Vector Provides Significant Protection in Rhesus Monkeys against All Four Serotypes of Dengue Virus. J. Virol. 82: 6927-6934 [Abstract] [Full Text]  
  • Lai, C.-Y., Tsai, W.-Y., Lin, S.-R., Kao, C.-L., Hu, H.-P., King, C.-C., Wu, H.-C., Chang, G.-J., Wang, W.-K. (2008). Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II. J. Virol. 82: 6631-6643 [Abstract] [Full Text]  
  • Thomas, L., Verlaeten, O., Cabie, A., Kaidomar, S., Moravie, V., Martial, J., Najioullah, F., Plumelle, Y., Fonteau, C., Dussart, P., Cesaire, R. (2008). Influence of the Dengue Serotype, Previous Dengue Infection, and Plasma Viral Load on Clinical Presentation and Outcome During a Dengue-2 and Dengue-4 Co-Epidemic. Am J Trop Med Hyg 78: 990-998 [Abstract] [Full Text]  
  • Jarman, R. G., Holmes, E. C., Rodpradit, P., Klungthong, C., Gibbons, R. V., Nisalak, A., Rothman, A. L., Libraty, D. H., Ennis, F. A., Mammen, M. P. Jr., Endy, T. P. (2008). Microevolution of Dengue Viruses Circulating among Primary School Children in Kamphaeng Phet, Thailand. J. Virol. 82: 5494-5500 [Abstract] [Full Text]  
  • Noisakran, S., Perng, G. C. (2008). Alternate Hypothesis on the Pathogenesis of Dengue Hemorrhagic Fever (DHF)/Dengue Shock Syndrome (DSS) in Dengue Virus Infection. Exp. Biol. Med. 233: 401-408 [Abstract] [Full Text]  
  • Dewi, B. E., Takasaki, T., Kurane, I. (2008). Peripheral blood mononuclear cells increase the permeability of dengue virus-infected endothelial cells in association with downregulation of vascular endothelial cadherin. J. Gen. Virol. 89: 642-652 [Abstract] [Full Text]  
  • Ramos, M. M., Mohammed, H., Zielinski-Gutierrez, E., Hayden, M. H., Lopez, J. L. R., Fournier, M., Trujillo, A. R., Burton, R., Brunkard, J. M., Anaya-Lopez, L., Banicki, A. A., Morales, P. K., Smith, B., Munoz, J. L., Waterman, S. H., The Dengue Serosurvey Working Group, (2008). Epidemic Dengue and Dengue Hemorrhagic Fever at the Texas-Mexico Border: Results of a Household-based Seroepidemiologic Survey, December 2005. Am J Trop Med Hyg 78: 364-369 [Abstract] [Full Text]  
  • Villar-Centeno, L. A., Diaz-Quijano, F. A., Martinez-Vega, R. A. (2008). Biochemical Alterations as Markers of Dengue Hemorrhagic Fever. Am J Trop Med Hyg 78: 370-374 [Abstract] [Full Text]  
  • Simasathien, S., Thomas, S. J., Watanaveeradej, V., Nisalak, A., Barberousse, C., Innis, B. L., Sun, W., Putnak, J. R., Eckels, K. H., Hutagalung, Y., Gibbons, R. V., Zhang, C., De La Barrera, R., Jarman, R. G., Chawachalasai, W., Mammen, M. P. Jr. (2008). Safety and Immunogenicity of a Tetravalent Live-attenuated Dengue Vaccine in Flavivirus Naive Children. Am J Trop Med Hyg 78: 426-433 [Abstract] [Full Text]  
  • Bernardo, L., Izquierdo, A., Prado, I., Rosario, D., Alvarez, M., Santana, E., Castro, J., Martinez, R., Rodriguez, R., Morier, L., Guillen, G., Guzman, M. G. (2008). Primary and Secondary Infections of Macaca fascicularis Monkeys with Asian and American Genotypes of Dengue Virus 2. CVI 15: 439-446 [Abstract] [Full Text]  
  • Falconar, A. K. I. (2008). Monoclonal Antibodies That Bind to Common Epitopes on the Dengue Virus Type 2 Nonstructural-1 and Envelope Glycoproteins Display Weak Neutralizing Activity and Differentiated Responses to Virulent Strains: Implications for Pathogenesis and Vaccines. CVI 15: 549-561 [Abstract] [Full Text]  
  • Huang, J.-H., Liao, T.-L., Chang, S.-F., Su, C.-L., Chien, L.-J., Kuo, Y.-C., Yang, C.-F., Lin, C.-C., Shu, P.-Y. (2007). Laboratory-based Dengue Surveillance in Taiwan, 2005: A Molecular Epidemiologic Study. Am J Trop Med Hyg 77: 903-909 [Abstract] [Full Text]  
  • Chen, L., Ewing, D., Subramanian, H., Block, K., Rayner, J., Alterson, K. D., Sedegah, M., Hayes, C., Porter, K., Raviprakash, K. (2007). A Heterologous DNA Prime-Venezuelan Equine Encephalitis Virus Replicon Particle Boost Dengue Vaccine Regimen Affords Complete Protection from Virus Challenge in Cynomolgus Macaques. J. Virol. 81: 11634-11639 [Abstract] [Full Text]  
  • Hapugoda, M. D., Batra, G., Abeyewickreme, W., Swaminathan, S., Khanna, N. (2007). Single Antigen Detects both Immunoglobulin M (IgM) and IgG Antibodies Elicited by All Four Dengue Virus Serotypes. CVI 14: 1505-1514 [Abstract] [Full Text]  
  • Imrie, A., Meeks, J., Gurary, A., Sukhbataar, M., Kitsutani, P., Effler, P., Zhao, Z. (2007). Differential Functional Avidity of Dengue Virus-Specific T-Cell Clones for Variant Peptides Representing Heterologous and Previously Encountered Serotypes. J. Virol. 81: 10081-10091 [Abstract] [Full Text]  
  • Tajima, S., Nukui, Y., Takasaki, T., Kurane, I. (2007). Characterization of the variable region in the 3' non-translated region of dengue type 1 virus. J. Gen. Virol. 88: 2214-2222 [Abstract] [Full Text]  
  • Wang, C.-C., Wu, C.-C., Liu, J.-W., Lin, A.-S., Liu, S.-F., Chung, Y.-H., Su, M.-C., Lee, I.-K., Lin, M.-C. (2007). Chest Radiographic Presentation in Patients with Dengue Hemorrhagic Fever. Am J Trop Med Hyg 77: 291-296 [Abstract] [Full Text]  
  • Klungthong, C., Gibbons, R. V., Thaisomboonsuk, B., Nisalak, A., Kalayanarooj, S., Thirawuth, V., Nutkumhang, N., Mammen, M. P. Jr., Jarman, R. G. (2007). Dengue Virus Detection Using Whole Blood for Reverse Transcriptase PCR and Virus Isolation. J. Clin. Microbiol. 45: 2480-2485 [Abstract] [Full Text]  
  • Appanna, R., Huat, T. L., See, L. L. C., Tan, P. L., Vadivelu, J., Devi, S. (2007). Cross-Reactive T-Cell Responses to the Nonstructural Regions of Dengue Viruses among Dengue Fever and Dengue Hemorrhagic Fever Patients in Malaysia. CVI 14: 969-977 [Abstract] [Full Text]  
  • Wang, C.-C., Liu, S.-F., Liao, S.-C., Lee, I.-K., Liu, J.-W., Lin, A.-S., Wu, C.-C., Chung, Y.-H., Lin, M.-C. (2007). Acute Respiratory Failure in Adult Patients with Dengue Virus Infection. Am J Trop Med Hyg 77: 151-158 [Abstract] [Full Text]  
  • Chen, H.-C., Hofman, F. M., Kung, J. T., Lin, Y.-D., Wu-Hsieh, B. A. (2007). Both Virus and Tumor Necrosis Factor Alpha Are Critical for Endothelium Damage in a Mouse Model of Dengue Virus-Induced Hemorrhage. J. Virol. 81: 5518-5526 [Abstract] [Full Text]  
  • Atkinson, M. P., Su, Z., Alphey, N., Alphey, L. S., Coleman, P. G., Wein, L. M. (2007). Analyzing the control of mosquito-borne diseases by a dominant lethal genetic system. Proc. Natl. Acad. Sci. USA 104: 9540-9545 [Abstract] [Full Text]  
  • Shiryaev, S. A., Ratnikov, B. I., Aleshin, A. E., Kozlov, I. A., Nelson, N. A., Lebl, M., Smith, J. W., Liddington, R. C., Strongin, A. Y. (2007). Switching the Substrate Specificity of the Two-Component NS2B-NS3 Flavivirus Proteinase by Structure-Based Mutagenesis. J. Virol. 81: 4501-4509 [Abstract] [Full Text]  
  • Yap, T. L., Xu, T., Chen, Y.-L., Malet, H., Egloff, M.-P., Canard, B., Vasudevan, S. G., Lescar, J. (2007). Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution. J. Virol. 81: 4753-4765 [Abstract] [Full Text]  
  • Falconar, A. K. I. (2007). Antibody Responses Are Generated to Immunodominant ELK/KLE-Type Motifs on the Nonstructural-1 Glycoprotein during Live Dengue Virus Infections in Mice and Humans: Implications for Diagnosis, Pathogenesis, and Vaccine Design. CVI 14: 493-504 [Abstract] [Full Text]  
  • RAJA, N. U., HOLMAN, D. H., WANG, D., RAVIPRAKASH, K., JUOMPAN, L. Y., DEITZ, S. B., LUO, M., ZHANG, J., PORTER, K. R., DONG, J. Y. (2007). INDUCTION OF BIVALENT IMMUNE RESPONSES BY EXPRESSION OF DENGUE VIRUS TYPE 1 AND TYPE 2 ANTIGENS FROM A SINGLE COMPLEX ADENOVIRAL VECTOR. Am J Trop Med Hyg 76: 743-751 [Abstract] [Full Text]  
  • Chen, Y.-C., Huang, H.-N., Lin, C.-T., Chen, Y.-F., King, C.-C., Wu, H.-C. (2007). Generation and Characterization of Monoclonal Antibodies against Dengue Virus Type 1 for Epitope Mapping and Serological Detection by Epitope-Based Peptide Antigens. CVI 14: 404-411 [Abstract] [Full Text]  
  • Chu, J. J. H., Yang, P. L. (2007). c-Src protein kinase inhibitors block assembly and maturation of dengue virus. Proc. Natl. Acad. Sci. USA 104: 3520-3525 [Abstract] [Full Text]  
  • Chareonsirisuthigul, T., Kalayanarooj, S., Ubol, S. (2007). Dengue virus (DENV) antibody-dependent enhancement of infection upregulates the production of anti-inflammatory cytokines, but suppresses anti-DENV free radical and pro-inflammatory cytokine production, in THP-1 cells. J. Gen. Virol. 88: 365-375 [Abstract] [Full Text]  
  • Holman, D. H., Wang, D., Raviprakash, K., Raja, N. U., Luo, M., Zhang, J., Porter, K. R., Dong, J. Y. (2007). Two Complex, Adenovirus-Based Vaccines That Together Induce Immune Responses to All Four Dengue Virus Serotypes. CVI 14: 182-189 [Abstract] [Full Text]  
  • Clyde, K., Kyle, J. L., Harris, E. (2006). Recent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and Pathogenesis. J. Virol. 80: 11418-11431 [Full Text]  
  • Yu, C.-Y., Hsu, Y.-W., Liao, C.-L., Lin, Y.-L. (2006). Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum Stress. J. Virol. 80: 11868-11880 [Abstract] [Full Text]  
  • ANDERSON, J. R., RICO-HESSE, R. (2006). AEDES AEGYPTI VECTORIAL CAPACITY IS DETERMINED BY THE INFECTING GENOTYPE OF DENGUE VIRUS. Am J Trop Med Hyg 75: 886-892 [Abstract] [Full Text]  
  • Dussart, P., Labeau, B., Lagathu, G., Louis, P., Nunes, M. R. T., Rodrigues, S. G., Storck-Herrmann, C., Cesaire, R., Morvan, J., Flamand, M., Baril, L. (2006). Evaluation of an Enzyme Immunoassay for Detection of Dengue Virus NS1 Antigen in Human Serum. CVI 13: 1185-1189 [Abstract] [Full Text]  
  • Umareddy, I., Chao, A., Sampath, A., Gu, F., Vasudevan, S. G. (2006). Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. J. Gen. Virol. 87: 2605-2614 [Abstract] [Full Text]  
  • Falconar, A. K. I., de Plata, E., Romero-Vivas, C. M. E. (2006). Altered Enzyme-Linked Immunosorbent Assay Immunoglobulin M (IgM)/IgG Optical Density Ratios Can Correctly Classify All Primary or Secondary Dengue Virus Infections 1 Day after the Onset of Symptoms, when All of the Viruses Can Be Isolated.. CVI 13: 1044-1051 [Abstract] [Full Text]  
  • Chen, J.-P., Lu, H.-L., Lai, S.-L., Campanella, G. S., Sung, J.-M., Lu, M.-Y., Wu-Hsieh, B. A., Lin, Y.-L., Lane, T. E., Luster, A. D., Liao, F. (2006). Dengue Virus Induces Expression of CXC Chemokine Ligand 10/IFN-{gamma}-Inducible Protein 10, Which Competitively Inhibits Viral Binding to Cell Surface Heparan Sulfate.. J. Immunol. 177: 3185-3192 [Abstract] [Full Text]  
  • Filomatori, C. V., Lodeiro, M. F., Alvarez, D. E., Samsa, M. M., Pietrasanta, L., Gamarnik, A. V. (2006). A 5' RNA element promotes dengue virus RNA synthesis on a circular genome. Genes Dev. 20: 2238-2249 [Abstract] [Full Text]  
  • Hsieh, M.-F., Lai, S.-L., Chen, J.-P., Sung, J.-M., Lin, Y.-L., Wu-Hsieh, B. A., Gerard, C., Luster, A., Liao, F. (2006). Both CXCR3 and CXCL10/IFN-Inducible Protein 10 Are Required for Resistance to Primary Infection by Dengue Virus. J. Immunol. 177: 1855-1863 [Abstract] [Full Text]  
  • Takhampunya, R., Ubol, S., Houng, H.-S., Cameron, C. E., Padmanabhan, R. (2006). Inhibition of dengue virus replication by mycophenolic acid and ribavirin. J. Gen. Virol. 87: 1947-1952 [Abstract] [Full Text]  
  • CHANTHAVANICH, P., LUXEMBURGER, C., SIRIVICHAYAKUL, C., LAPPHRA, K., PENGSAA, K., YOKSAN, S., SABCHAREON, A., LANG, J. (2006). IMMUNE RESPONSE AND OCCURRENCE OF DENGUE INFECTION IN THAI CHILDREN THREE TO EIGHT YEARS AFTER VACCINATION WITH LIVE ATTENUATED TETRAVALENT DENGUE VACCINE.. Am J Trop Med Hyg 75: 26-28 [Abstract] [Full Text]  
  • KUNIHOLM, M. H., WOLFE, N. D., HUANG, C. Y.-H., MPOUDI-NGOLE, E., TAMOUFE, U., BURKE, D. S., GUBLER, D. J. (2006). SEROPREVALENCE AND DISTRIBUTION OF FLAVIVIRIDAE, TOGAVIRIDAE, AND BUNYAVIRIDAE ARBOVIRAL INFECTIONS IN RURAL CAMEROONIAN ADULTS. Am J Trop Med Hyg 74: 1078-1083 [Abstract] [Full Text]  
  • Bennett, S. N., Holmes, E. C., Chirivella, M., Rodriguez, D. M., Beltran, M., Vorndam, V., Gubler, D. J., McMillan, W. O. (2006). Molecular evolution of dengue 2 virus in Puerto Rico: positive selection in the viral envelope accompanies clade reintroduction.. J. Gen. Virol. 87: 885-893 [Abstract] [Full Text]  
  • HUNG, N. T., LAN, N. T., LEI, H.-Y., LIN, Y.-S., LIEN, L. B., HUANG, K.-J., LIN, C.-F., HA, D. Q., HUONG, V. T. Q., MY, L. T., YEH, T.-M., HUANG, J.-H., LIU, C.-C., HALSTEAD, S. B. (2006). VOLUME REPLACEMENT IN INFANTS WITH DENGUE HEMORRHAGIC FEVER/DENGUE SHOCK SYNDROME. Am J Trop Med Hyg 74: 684-691 [Abstract] [Full Text]  
  • Lennon, J. L., Coombs, D. W. (2006). Child-invented health education games: A case study for dengue fever. Simulation Gaming 37: 88-97 [Abstract]  
  • Aoki, C., Hidari, K. I.P.J., Itonori, S., Yamada, A., Takahashi, N., Kasama, T., Hasebe, F., Islam, M. A., Hatano, K., Matsuoka, K., Taki, T., Guo, C.-T., Takahashi, T., Sakano, Y., Suzuki, T., Miyamoto, D., Sugita, M., Terunuma, D., Morita, K., Suzuki, Y. (2006). Identification and characterization of carbohydrate molecules in Mammalian cells recognized by dengue virus type 2.. J Biochem 139: 607-614 [Abstract] [Full Text]  
  • Calvert, A. E., Huang, C. Y.-H., Kinney, R. M., Roehrig, J. T. (2006). Non-structural proteins of dengue 2 virus offer limited protection to interferon-deficient mice after dengue 2 virus challenge. J. Gen. Virol. 87: 339-346 [Abstract] [Full Text]  
  • KHANAM, S., ETEMAD, B., KHANNA, N., SWAMINATHAN, S. (2006). INDUCTION OF NEUTRALIZING ANTIBODIES SPECIFIC TO DENGUE VIRUS SEROTYPES 2 AND 4 BY A BIVALENT ANTIGEN COMPOSED OF LINKED ENVELOPE DOMAINS III OF THESE TWO SEROTYPES. Am J Trop Med Hyg 74: 266-277 [Abstract] [Full Text]  
  • AnandaRao, R., Swaminathan, S., Fernando, S., Jana, A. M., Khanna, N. (2006). Recombinant Multiepitope Protein for Early Detection of Dengue Infections. CVI 13: 59-67 [Abstract] [Full Text]  
  • CHEN, L.-C., LEI, H.-Y., LIU, C.-C., SHIESH, S.-C., CHEN, S.-H., LIU, H.-S., LIN, Y.-S., WANG, S.-T., SHYU, H.-W., YEH, T.-M. (2006). CORRELATION OF SERUM LEVELS OF MACROPHAGE MIGRATION INHIBITORY FACTOR WITH DISEASE SEVERITY AND CLINICAL OUTCOME IN DENGUE PATIENTS. Am J Trop Med Hyg 74: 142-147 [Abstract] [Full Text]  
  • Carrington, C. V. F., Foster, J. E., Pybus, O. G., Bennett, S. N., Holmes, E. C. (2005). Invasion and Maintenance of Dengue Virus Type 2 and Type 4 in the Americas. J. Virol. 79: 14680-14687 [Abstract] [Full Text]  
  • Matheus, S., Deparis, X., Labeau, B., Lelarge, J., Morvan, J., Dussart, P. (2005). Use of Four Dengue Virus Antigens for Determination of Dengue Immune Status by Enzyme-Linked Immunosorbent Assay of Immunoglobulin G Avidity. J. Clin. Microbiol. 43: 5784-5786 [Abstract] [Full Text]  
  • Helt, A.-M., Harris, E. (2005). S-Phase-Dependent Enhancement of Dengue Virus 2 Replication in Mosquito Cells, but Not in Human Cells. J. Virol. 79: 13218-13230 [Abstract] [Full Text]  
  • Johnson, B. W., Russell, B. J., Lanciotti, R. S. (2005). Serotype-Specific Detection of Dengue Viruses in a Fourplex Real-Time Reverse Transcriptase PCR Assay. J. Clin. Microbiol. 43: 4977-4983 [Abstract] [Full Text]  
  • Wilder-Smith, A., Schwartz, E. (2005). Dengue in Travelers. NEJM 353: 924-932 [Full Text]  
  • Xu, T., Sampath, A., Chao, A., Wen, D., Nanao, M., Chene, P., Vasudevan, S. G., Lescar, J. (2005). Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A. J. Virol. 79: 10278-10288 [Abstract] [Full Text]  
  • Li, J., Lim, S. P., Beer, D., Patel, V., Wen, D., Tumanut, C., Tully, D. C., Williams, J. A., Jiricek, J., Priestle, J. P., Harris, J. L., Vasudevan, S. G. (2005). Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries. J. Biol. Chem. 280: 28766-28774 [Abstract] [Full Text]  
  • CHIU, Y.-C., WU, K.-L., KUO, C.-H., HU, T.-H., CHOU, Y.-P., CHUAH, S.-K., KUO, C.-M., KEE, K.-M., CHANGCHIEN, C.-S., LIU, J.-W., CHIU, K.-W. (2005). ENDOSCOPIC FINDINGS AND MANAGEMENT OF DENGUE PATIENTS WITH UPPER GASTROINTESTINAL BLEEDING. Am J Trop Med Hyg 73: 441-444 [Abstract] [Full Text]  
  • DIALLO, M., SALL, A. A., MONCAYO, A. C., BA, Y., FERNANDEZ, Z., ORTIZ, D., COFFEY, L. L., MATHIOT, C., TESH, R. B., WEAVER, S. C. (2005). POTENTIAL ROLE OF SYLVATIC AND DOMESTIC AFRICAN MOSQUITO SPECIES IN DENGUE EMERGENCE. Am J Trop Med Hyg 73: 445-449 [Abstract] [Full Text]  
  • Yon, C., Teramoto, T., Mueller, N., Phelan, J., Ganesh, V. K., Murthy, K. H. M., Padmanabhan, R. (2005). Modulation of the Nucleoside Triphosphatase/RNA Helicase and 5'-RNA Triphosphatase Activities of Dengue Virus Type 2 Nonstructural Protein 3 (NS3) by Interaction with NS5, the RNA-dependent RNA Polymerase. J. Biol. Chem. 280: 27412-27419 [Abstract] [Full Text]  
  • Ho, L.-J., Hung, L.-F., Weng, C.-Y., Wu, W.-L., Chou, P., Lin, Y.-L., Chang, D.-M., Tai, T.-Y., Lai, J.-H. (2005). Dengue Virus Type 2 Antagonizes IFN-{alpha} but Not IFN-{gamma} Antiviral Effect via Down-Regulating Tyk2-STAT Signaling in the Human Dendritic Cell. J. Immunol. 174: 8163-8172 [Abstract] [Full Text]  
  • Matheus, S., Deparis, X., Labeau, B., Lelarge, J., Morvan, J., Dussart, P. (2005). Discrimination between Primary and Secondary Dengue Virus Infection by an Immunoglobulin G Avidity Test Using a Single Acute-Phase Serum Sample. J. Clin. Microbiol. 43: 2793-2797 [Abstract] [Full Text]  
  • Lindegren, G., Vene, S., Lundkvist, A., Falk, K. I. (2005). Optimized Diagnosis of Acute Dengue Fever in Swedish Travelers by a Combination of Reverse Transcription-PCR and Immunoglobulin M Detection. J. Clin. Microbiol. 43: 2850-2855 [Abstract] [Full Text]  
  • CLARK, D. V., MAMMEN, M. P. JR., NISALAK, A., PUTHIMETHEE, V., ENDY, T. P. (2005). ECONOMIC IMPACT OF DENGUE FEVER/DENGUE HEMORRHAGIC FEVER IN THAILAND AT THE FAMILY AND POPULATION LEVELS. Am J Trop Med Hyg 72: 786-791 [Abstract] [Full Text]  
  • Blaney, J. E. Jr., Matro, J. M., Murphy, B. R., Whitehead, S. S. (2005). Recombinant, Live-Attenuated Tetravalent Dengue Virus Vaccine Formulations Induce a Balanced, Broad, and Protective Neutralizing Antibody Response against Each of the Four Serotypes in Rhesus Monkeys. J. Virol. 79: 5516-5528 [Abstract] [Full Text]  
  • Kinney, R. M., Huang, C. Y.-H., Rose, B. C., Kroeker, A. D., Dreher, T. W., Iversen, P. L., Stein, D. A. (2005). Inhibition of Dengue Virus Serotypes 1 to 4 in Vero Cell Cultures with Morpholino Oligomers. J. Virol. 79: 5116-5128 [Abstract] [Full Text]  
  • Matsuda, T., Almasan, A., Tomita, M., Tamaki, K., Saito, M., Tadano, M., Yagita, H., Ohta, T., Mori, N. (2005). Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand. J. Gen. Virol. 86: 1055-1065 [Abstract] [Full Text]  
  • HUNG, N. T., LAN, N. T., LEI, H.-Y., LIN, Y.-S., LIEN, L. B., HUANG, K.-J., LIN, C.-F., HA, D. Q., HUONG, V. T. Q., MY, L. T., YEH, T.-M., HUANG, J.-H., LIU, C.-C., HALSTEAD, S. B. (2005). ASSOCIATION BETWEEN SEX, NUTRITIONAL STATUS, SEVERITY OF DENGUE HEMORRHAGIC FEVER, AND IMMUNE STATUS IN INFANTS WITH DENGUE HEMORRHAGIC FEVER. Am J Trop Med Hyg 72: 370-374 [Abstract] [Full Text]  
  • Lin, C.-F., Chiu, S.-C., Hsiao, Y.-L., Wan, S.-W., Lei, H.-Y., Shiau, A.-L., Liu, H.-S., Yeh, T.-M., Chen, S.-H., Liu, C.-C., Lin, Y.-S. (2005). Expression of Cytokine, Chemokine, and Adhesion Molecules during Endothelial Cell Activation Induced by Antibodies against Dengue Virus Nonstructural Protein 1. J. Immunol. 174: 395-403 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»