This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Breitschwerdt, E. B.
Right arrow Articles by Kordick, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Breitschwerdt, E. B.
Right arrow Articles by Kordick, D. L.

 Previous Article  |  Next Article 

Clinical Microbiology Reviews, July 2000, p. 428-438, Vol. 13, No. 3
0893-8512/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Bartonella Infection in Animals: Carriership, Reservoir Potential, Pathogenicity, and Zoonotic Potential for Human Infection

Edward B. Breitschwerdt* and Dorsey L. Kordick

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina

Recent observations have begun to support a role for Bartonella spp. as animal as well as human pathogens. Bartonella spp. are vector-transmitted, blood-borne, intracellular, gram-negative bacteria that can induce prolonged infection in the host. Persistent infections in domestic and wild animals result in a substantial reservoir of Bartonella organisms in nature that can serve as a source for inadvertent human infection. The prevalence of bacteremia can range from 50 to 95% in selected rodent, cat, deer, and cattle populations. Dogs infected with Bartonella spp. can develop lameness, endocarditis, granulomatous lymphadenitis, and peliosis hepatis, lesions that have also been reported in association with human infection. Understanding the role of Bartonella spp. as pathogens in cats and other wild or domestic animals awaits the results of additional studies. Considering the extensive animal reservoirs and the large number of insects that have been implicated in the transmission of Bartonella spp., both animal and human exposure to these organisms may be more substantial than is currently believed.

* Corresponding author. Mailing address: Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606. Phone: (919) 513-6234. Fax: (919) 513-6336. E-mail: ed_breitschwerdt{at}ncsu.edu.

Clinical Microbiology Reviews, July 2000, p. 428-438, Vol. 13, No. 3
0893-8512/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Bai, Y., Kosoy, M. Y., Lerdthusnee, K., Peruski, L. F., Richardson, J. H. (2009). Prevalence and Genetic Heterogeneity of Bartonella Strains Cultured from Rodents from 17 Provinces in Thailand. Am J Trop Med Hyg 81: 811-816 [Abstract] [Full Text]  
  • Varanat, M., Maggi, R. G., Linder, K. E., Horton, S., Breitschwerdt, E. B. (2009). Cross-contamination in the Molecular Detection of Bartonella from Paraffin-embedded Tissues. Vet Pathol 46: 940-944 [Abstract] [Full Text]  
  • Fournier, P.-E., Couderc, C., Buffet, S., Flaudrops, C., Raoult, D. (2009). Rapid and cost-effective identification of Bartonella species using mass spectrometry. J Med Microbiol 58: 1154-1159 [Abstract] [Full Text]  
  • Probert, W., Louie, J. K., Tucker, J. R., Longoria, R., Hogue, R., Moler, S., Graves, M., Palmer, H. J., Cassady, J., Fritz, C. L. (2009). Meningitis Due to a "Bartonella washoensis"-Like Human Pathogen. J. Clin. Microbiol. 47: 2332-2335 [Abstract] [Full Text]  
  • Robinson, M. T., Hillman, T., Langton, D. A., Shaw, S. E. (2009). Bartonella clarridgeiae in a cat in the UK. Vet Rec. 164: 58-59 [Full Text]  
  • Lin, J.-W., Chen, C.-Y., Chen, W.-C., Chomel, B. B., Chang, C.-C. (2008). Isolation of Bartonella species from rodents in Taiwan including a strain closely related to 'Bartonella rochalimae' from Rattus norvegicus. J Med Microbiol 57: 1496-1501 [Abstract] [Full Text]  
  • Maggi, R. G., Raverty, S. A., Lester, S. J., Huff, D. G., Haulena, M., Ford, S. L., Nielsen, O., Robinson, J. H., Breitschwerdt, E. B. (2008). BARTONELLA HENSELAE IN CAPTIVE AND HUNTER-HARVESTED BELUGA (DELPHINAPTERUS LEUCAS). J Wildl Dis 44: 871-877 [Abstract] [Full Text]  
  • Riess, T., Dietrich, F., Schmidt, K. V., Kaiser, P. O., Schwarz, H., Schafer, A., Kempf, V. A. J. (2008). Analysis of a Novel Insect Cell Culture Medium-Based Growth Medium for Bartonella Species. Appl. Environ. Microbiol. 74: 5224-5227 [Abstract] [Full Text]  
  • Cadenas, M. B., Bradley, J., Maggi, R. G., Takara, M., Hegarty, B. C., Breitschwerdt, E. B. (2008). Molecular Characterization of Bartonella vinsonii subsp. berkhoffii Genotype III. J. Clin. Microbiol. 46: 1858-1860 [Abstract] [Full Text]  
  • Li, D. M., Liu, Q. Y., Yu, D. Z., Zhang, J. Z., Gong, Z. D., Song, X. P. (2007). PHYLOGENETIC ANALYSIS OF BARTONELLA DETECTED IN RODENT FLEAS IN YUNNAN, CHINA. J Wildl Dis 43: 609-617 [Abstract] [Full Text]  
  • Henn, J. B., Gabriel, M. W., Kasten, R. W., Brown, R. N., Theis, J. H., Foley, J. E., Chomel, B. B. (2007). Gray Foxes (Urocyon cinereoargenteus) as a Potential Reservoir of a Bartonella clarridgeiae-Like Bacterium and Domestic Dogs as Part of a Sentinel System for Surveillance of Zoonotic Arthropod-Borne Pathogens in Northern California. J. Clin. Microbiol. 45: 2411-2418 [Abstract] [Full Text]  
  • Berghoff, J., Viezens, J., Guptill, L., Fabbi, M., Arvand, M. (2007). Bartonella henselae exists as a mosaic of different genetic variants in the infected host. Microbiology 153: 2045-2051 [Abstract] [Full Text]  
  • Lindroos, H., Vinnere, O., Mira, A., Repsilber, D., Naslund, K., Andersson, S. G. E. (2006). Genome Rearrangements, Deletions, and Amplifications in the Natural Population of Bartonella henselae. J. Bacteriol. 188: 7426-7439 [Abstract] [Full Text]  
  • DE SOUSA, R., EDOUARD-FOURNIER, P., SANTOS-SILVA, M., AMARO, F., BACELLAR, F., RAOULT, D. (2006). MOLECULAR DETECTION OF RICKETTSIA FELIS, RICKETTSIA TYPHI AND TWO GENOTYPES CLOSELY RELATED TO BARTONELLA ELIZABETHAE.. Am J Trop Med Hyg 75: 727-731 [Abstract] [Full Text]  
  • Jardine, C., Waldner, C., Wobeser, G., Leighton, F. A. (2006). EFFECT OF EXPERIMENTAL ECTOPARASITE CONTROL ON BARTONELLA INFECTIONS IN WILD RICHARDSON'S GROUND SQUIRRELS. J Wildl Dis 42: 750-758 [Abstract] [Full Text]  
  • Werner, J. A., Feng, S., Kasten, R. W., Hodzic, E., Chomel, B. B., Barthold, S. W. (2006). Cloning, Characterization, and Expression of Bartonella henselae p26.. CVI 13: 830-836 [Abstract] [Full Text]  
  • Kampfer, P., Rossello-Mora, R., Scholz, H. C., Welinder-Olsson, C., Falsen, E., Busse, H.-J. (2006). Description of Pseudochrobactrum gen. nov., with the two species Pseudochrobactrum asaccharolyticum sp. nov. and Pseudochrobactrum saccharolyticum sp. nov.. Int. J. Syst. Evol. Microbiol. 56: 1823-1829 [Abstract] [Full Text]  
  • Saunders, G. K., Monroe, W. E. (2006). Systemic Granulomatous Disease and Sialometaplasia in a Dog with Bartonella Infection. Vet Pathol 43: 391-392 [Abstract] [Full Text]  
  • Maillard, R., Grimard, B., Chastant-Maillard, S., Chomel, B., Delcroix, T., Gandoin, C., Bouillin, C., Halos, L., Vayssier-Taussat, M., Boulouis, H.-J. (2006). Effects of Cow Age and Pregnancy on Bartonella Infection in a Herd of Dairy Cattle. J. Clin. Microbiol. 44: 42-46 [Abstract] [Full Text]  
  • Koehler, J. E., Duncan, L. M. (2005). Case records of the Massachusetts General Hospital. Case 30-2005. A 56-year-old man with Fever and axillary lymphadenopathy.. NEJM 353: 1387-1394 [Full Text]  
  • Maggi, R. G., Duncan, A. W., Breitschwerdt, E. B. (2005). Novel Chemically Modified Liquid Medium That Will Support the Growth of Seven Bartonella Species. J. Clin. Microbiol. 43: 2651-2655 [Abstract] [Full Text]  
  • Gilmore, R. D. Jr., Bellville, T. M., Sviat, S. L., Frace, M. (2005). The Bartonella vinsonii subsp. arupensis Immunodominant Surface Antigen BrpA Gene, Encoding a 382-Kilodalton Protein Composed of Repetitive Sequences, Is a Member of a Multigene Family Conserved among Bartonella Species. Infect. Immun. 73: 3128-3136 [Abstract] [Full Text]  
  • Breitschwerdt, E. B., Hegarty, B. C., Maggi, R., Hawkins, E., Dyer, P. (2005). Bartonella Species as a Potential Cause of Epistaxis in Dogs. J. Clin. Microbiol. 43: 2529-2533 [Abstract] [Full Text]  
  • PONS, I., SANFELIU, I., QUESADA, M., ANTON, E., SAMPERE, M., FONT, B., PLA, J., SEGURA, F. (2005). PREVALENCE OF BARTONELLA HENSELAE IN CATS IN CATALONIA, SPAIN. Am J Trop Med Hyg 72: 453-457 [Abstract] [Full Text]  
  • Maggi, R. G., Breitschwerdt, E. B. (2005). Potential Limitations of the 16S-23S rRNA Intergenic Region for Molecular Detection of Bartonella Species. J. Clin. Microbiol. 43: 1171-1176 [Abstract] [Full Text]  
  • Pretorius, A.-M., Beati, L., Birtles, R. J. (2004). Diversity of bartonellae associated with small mammals inhabiting Free State province, South Africa. Int. J. Syst. Evol. Microbiol. 54: 1959-1967 [Abstract] [Full Text]  
  • Dehio, C., Sauder, U., Hiestand, R. (2004). Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a Blood-Sucking Arthropod Causing Deer Ked Dermatitis. J. Clin. Microbiol. 42: 5320-5323 [Abstract] [Full Text]  
  • Halos, L., Jamal, T., Maillard, R., Girard, B., Guillot, J., Chomel, B., Vayssier-Taussat, M., Boulouis, H.-J. (2004). Role of Hippoboscidae Flies as Potential Vectors of Bartonella spp. Infecting Wild and Domestic Ruminants. Appl. Environ. Microbiol. 70: 6302-6305 [Abstract] [Full Text]  
  • Avidor, B., Graidy, M., Efrat, G., Leibowitz, C., Shapira, G., Schattner, A., Zimhony, O., Giladi, M. (2004). Bartonella koehlerae, a New Cat-Associated Agent of Culture-Negative Human Endocarditis. J. Clin. Microbiol. 42: 3462-3468 [Abstract] [Full Text]  
  • Gundi, V. A. K. B., Davoust, B., Khamis, A., Boni, M., Raoult, D., La Scola, B. (2004). Isolation of Bartonella rattimassiliensis sp. nov. and Bartonella phoceensis sp. nov. from European Rattus norvegicus. J. Clin. Microbiol. 42: 3816-3818 [Abstract] [Full Text]  
  • Alsmark, C. M., Frank, A. C., Karlberg, E. O., Legault, B.-A., Ardell, D. H., Canback, B., Eriksson, A.-S., Naslund, A. K., Handley, S. A., Huvet, M., La Scola, B., Holmberg, M., Andersson, S. G. E. (2004). The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc. Natl. Acad. Sci. USA 101: 9716-9721 [Abstract] [Full Text]  
  • Rolain, J. M., Brouqui, P., Koehler, J. E., Maguina, C., Dolan, M. J., Raoult, D. (2004). Recommendations for Treatment of Human Infections Caused by Bartonella Species. Antimicrob. Agents Chemother. 48: 1921-1933 [Full Text]  
  • Maillard, R., Riegel, P., Barrat, F., Bouillin, C., Thibault, D., Gandoin, C., Halos, L., Demanche, C., Alliot, A., Guillot, J., Piemont, Y., Boulouis, H.-J., Vayssier-Taussat, M. (2004). Bartonella chomelii sp. nov., isolated from French domestic cattle (Bos taurus). Int. J. Syst. Evol. Microbiol. 54: 215-220 [Abstract] [Full Text]  
  • Ketring, K. L., Zuckerman, E. E., Hardy, W. D. Jr. (2004). Bartonella: A New Etiological Agent of Feline Ocular Disease. Journal of the American Animal Hospital Association 40: 6-12 [Full Text]  
  • Chomel, B. B., Wey, A. C., Kasten, R. W. (2003). Isolation of Bartonella washoensis from a Dog with Mitral Valve Endocarditis. J. Clin. Microbiol. 41: 5327-5332 [Abstract] [Full Text]  
  • Gilmore, R. D. Jr., Carpio, A. M., Kosoy, M. Y., Gage, K. L. (2003). Molecular Characterization of the sucB Gene Encoding the Immunogenic Dihydrolipoamide Succinyltransferase Protein of Bartonella vinsonii subsp. berkhoffii and Bartonella quintana. Infect. Immun. 71: 4818-4822 [Abstract] [Full Text]  
  • Rolain, J.-M., Maurin, M., Mallet, M.-N., Parzy, D., Raoult, D. (2003). Culture and Antibiotic Susceptibility of Bartonella quintana in Human Erythrocytes. Antimicrob. Agents Chemother. 47: 614-619 [Abstract] [Full Text]  
  • Kosoy, M., Murray, M., Gilmore, R. D. Jr., Bai, Y., Gage, K. L. (2003). Bartonella Strains from Ground Squirrels Are Identical to Bartonella washoensis Isolated from a Human Patient. J. Clin. Microbiol. 41: 645-650 [Abstract] [Full Text]  
  • Mexas, A. M., Hancock, S. I., Breitschwerdt, E. B. (2002). Bartonella henselae and Bartonella elizabethae as Potential Canine Pathogens. J. Clin. Microbiol. 40: 4670-4674 [Abstract] [Full Text]  
  • GREUB, G., RAOULT, D. (2002). Bartonella: new explanations for old diseases. J Med Microbiol 51: 915-923 [Full Text]  
  • Zeaiter, Z., Liang, Z., Raoult, D. (2002). Genetic Classification and Differentiation of Bartonella Species Based on Comparison of Partial ftsZ Gene Sequences. J. Clin. Microbiol. 40: 3641-3647 [Abstract] [Full Text]  
  • Maurin, M., Rolain, J. M., Raoult, D. (2002). Comparison of In-House and Commercial Slides for Detection by Immunofluorescence of Immunoglobulins G and M against Bartonella henselae and Bartonella quintana. CVI 9: 1004-1009 [Abstract] [Full Text]  
  • Yamamoto, K., Chomel, B. B., Kasten, R. W., Hew, C. M., Weber, D. K., Lee, W. I., Droz, S., Koehler, J. E. (2002). Experimental Infection of Domestic Cats with Bartonella koehlerae and Comparison of Protein and DNA Profiles with Those of Other Bartonella Species Infecting Felines. J. Clin. Microbiol. 40: 466-474 [Abstract] [Full Text]  
  • Jacomo, V., Kelly, P. J., Raoult, D. (2002). Natural History of Bartonella Infections (an Exception to Koch's Postulate). CVI 9: 8-18 [Full Text]  
  • Chomel, B. B., Mac Donald, K. A., Kasten, R. W., Chang, C.-C., Wey, A. C., Foley, J. E., Thomas, W. P., Kittleson, M. D. (2001). Aortic Valve Endocarditis in a Dog Due to Bartonella clarridgeiae. J. Clin. Microbiol. 39: 3548-3554 [Abstract] [Full Text]  
  • Boulouis, H. J., Barrat, F., Bermond, D., Bernex, F., Thibault, D., Heller, R., Fontaine, J.-J., Piemont, Y., Chomel, B. B. (2001). Kinetics of Bartonella birtlesii Infection in Experimentally Infected Mice and Pathogenic Effect on Reproductive Functions. Infect. Immun. 69: 5313-5317 [Abstract] [Full Text]  
  • Eskow, E., Rao, R.-V. S., Mordechai, E. (2001). Concurrent Infection of the Central Nervous System by Borrelia burgdorferi and Bartonella henselae: Evidence for a Novel Tick-borne Disease Complex. Arch Neurol 58: 1357-1363 [Abstract] [Full Text]  
  • Houpikian, P., Raoult, D. (2001). 16S/23S rRNA Intergenic Spacer Regions for Phylogenetic Analysis, Identification, and Subtyping of Bartonella Species. J. Clin. Microbiol. 39: 2768-2778 [Abstract] [Full Text]  
  • Schulein, R., Seubert, A., Gille, C., Lanz, C., Hansmann, Y., Piemont, Y., Dehio, C. (2001). Invasion and Persistent Intracellular Colonization of Erythrocytes: A Unique Parasitic Strategy of the Emerging Pathogen Bartonella. JEM 193: 1077-1086 [Abstract] [Full Text]  
  • Chang, C. C., Chomel, B. B., Kasten, R. W., Romano, V., Tietze, N. (2001). Molecular Evidence of Bartonella spp. in Questing Adult Ixodes pacificus Ticks in California. J. Clin. Microbiol. 39: 1221-1226 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»