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Clinical Microbiology Reviews, July 2002, p. 327-328, Vol. 15, No. 3
0893-8512/02/$04.00+0     DOI: 10.1128/CMR.15.3.327-328.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

GUEST COMMENTARY

Culture of Protozoan Parasites

Govinda S. Visvesvara1* and Lynne S. Garcia2

Centers for Disease Control and Prevention, Atlanta, Georgia 30341,1 LSG & Associates, Santa Monica, California 904022

SUMMARY

The in vitro culture of protozoan parasites involves highly complex procedures, which are subject to many variables. These parasites have very complex life cycles and, depending on the life cycle stage, may require different culture parameters. However, in vitro cultivation is important for many reasons, some of which include: diagnosis, antigen and antibody production, assessment of parasite immune modulating capabilities, drug screening, improvements in chemotherapy, differentiation of clinical isolates, determination of strain differences, vaccine production, development of attenuated strains, and the continued supply of viable organisms for studying host-parasite interactions.

* Corresponding author. Mailing address: Division of Parasitic Diseases, MS F36, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341-3724. Phone: (770) 488-4417. Fax: (770) 488-4253. E-mail: gsv1{at}cdc.gov.

FOOTNOTES

The views expressed in this Commentary do not necessarily reflect the views of the journal or of ASM.

Clinical Microbiology Reviews, July 2002, p. 327-328, Vol. 15, No. 3
0893-8512/02/$04.00+0     DOI: 10.1128/CMR.15.3.327-328.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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