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Clinical Microbiology Reviews, July 2007, p. 478-488, Vol. 20, No. 3
0893-8512/07/$08.00+0     doi:10.1128/CMR.00006-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Epidemiology of Human Immunodeficiency Virus in the United States

Susan Hariri and Matthew T. McKenna*

HIV Incidence and Case Surveillance Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention (Proposed), Centers for Disease Control and Prevention, Atlanta, Georgia

The human immunodeficiency virus (HIV) epidemic emerged in the early 1980s with HIV infection as a highly lethal disease among men who have sex with men and among frequent recipients of blood product transfusions. Advances in the treatment of HIV infection have resulted in a fundamental shift in its epidemiology, to a potentially chronic and manageable condition. However, challenges in the prevention of this infection remain. In particular, increasing evidence suggests that transmission of drug-resistant virus is becoming more common and that the epidemic is having a profound impact on morbidity and mortality in ethnic and racial minority subgroups in the United States. New population-based data collection systems designed to describe trends in behaviors associated with HIV transmission and better methods for measuring the true incidence of transmission will better elucidate the characteristics of HIV infection in the United States and inform future public health policies.

* Corresponding author. Mailing address: CDC, NCCDPHP, 1600 Clifton Road, MS E 47, Atlanta, GA 30333. Phone: (404) 639-2050. Fax: (404) 639-2980. E-mail: mtm1{at}cdc.gov

Clinical Microbiology Reviews, July 2007, p. 478-488, Vol. 20, No. 3
0893-8512/07/$08.00+0     doi:10.1128/CMR.00006-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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  • Michalowski, D., Chitima-Matsiga, R., Held, D. M., Burke, D. H. (2008). Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases. Nucleic Acids Res 36: 7124-7135 [Abstract] [Full Text]  


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