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Clinical Microbiology Reviews, January 2009, p. 37-45, Vol. 22, No. 1
0893-8512/09/$08.00+0     doi:10.1128/CMR.00002-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Current Issues and Considerations Regarding Trichomoniasis and Human Immunodeficiency Virus in African-Americans

Shira C. Shafir,1* Frank J. Sorvillo,1,2 and Lisa Smith1,2

Department of Epidemiology, UCLA School of Public Health, Center for Health Sciences, 650 Charles E. Young Drive, Los Angeles, California 90024,1 Data Collection and Analysis Unit, Los Angeles County Department of Health Services, 313 N. Figueroa Avenue #127, Los Angeles, California 900122

Trichomonas vaginalis has long been recognized as one of the most prevalent sexually transmitted infections. However, it is only in recent years that it has been appreciated that Trichomonas may play a critical role in amplifying human immunodeficiency virus (HIV) transmission. Given the evidence that T. vaginalis likely promotes HIV infection, the apparent high level of Trichomonas infection in the African-American community is cause for concern. Even if T. vaginalis increases the risk of HIV transmission by a small or modest amount, it translates into a sizable population effect since Trichomonas is so common in this community. Therefore, control of trichomoniasis may represent an important avenue of control for the prevention of HIV transmission, particularly among African-Americans.

* Corresponding author. Mailing address: UCLA School of Public Health, Department of Epidemiology, Center for Health Sciences, Room 21-245, 650 Charles E. Young Drive, Los Angeles, CA 90024. Phone: (310) 206-7942. Fax: (310) 206-6039. E-mail: sshafir{at}ucla.edu

Clinical Microbiology Reviews, January 2009, p. 37-45, Vol. 22, No. 1
0893-8512/09/$08.00+0     doi:10.1128/CMR.00002-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Westrop, G. D., Georg, I., Coombs, G. H. (2009). The Mercaptopyruvate Sulfurtransferase of Trichomonas vaginalis Links Cysteine Catabolism to the Production of Thioredoxin Persulfide. J. Biol. Chem. 284: 33485-33494 [Abstract] [Full Text]  


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