This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kaper, J. B.
Right arrow Articles by Levine, M. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kaper, J. B.
Right arrow Articles by Levine, M. M.

 Previous Article  |  Next Article 

Clinical Microbiology Reviews, Jan 1995, 48-86, Vol 8, No. 1
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Cholera [published erratum appears in Clin Microbiol Rev 1995 Apr;8(2):316]

JB Kaper, JG Morris Jr and MM Levine
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore 21201.

Despite more than a century of study, cholera still presents challenges and surprises to us. Throughout most of the 20th century, cholera was caused by Vibrio cholerae of the O1 serogroup and the disease was largely confined to Asia and Africa. However, the last decade of the 20th century has witnessed two major developments in the history of this disease. In 1991, a massive outbreak of cholera started in South America, the one continent previously untouched by cholera in this century. In 1992, an apparently new pandemic caused by a previously unknown serogroup of V. cholerae (O139) began in India and Bangladesh. The O139 epidemic has been occurring in populations assumed to be largely immune to V. cholerae O1 and has rapidly spread to many countries including the United States. In this review, we discuss all aspects of cholera, including the clinical microbiology, epidemiology, pathogenesis, and clinical features of the disease. Special attention will be paid to the extraordinary advances that have been made in recent years in unravelling the molecular pathogenesis of this infection and in the development of new generations of vaccines to prevent it.


This article has been cited by other articles:

  • Glenn, G. M., Francis, D. H., Danielsen, E. M. (2009). Toxin-Mediated Effects on the Innate Mucosal Defenses: Implications for Enteric Vaccines. Infect. Immun. 77: 5206-5215 [Abstract] [Full Text]  
  • Huang, J., Zhu, Y., Wen, H., Zhang, J., Huang, S., Niu, J., Li, Q. (2009). Quadruplex Real-Time PCR Assay for Detection and Identification of Vibrio cholerae O1 and O139 Strains and Determination of Their Toxigenic Potential. Appl. Environ. Microbiol. 75: 6981-6985 [Abstract] [Full Text]  
  • Chun, J., Grim, C. J., Hasan, N. A., Lee, J. H., Choi, S. Y., Haley, B. J., Taviani, E., Jeon, Y.-S., Kim, D. W., Lee, J.-H., Brettin, T. S., Bruce, D. C., Challacombe, J. F., Detter, J. C., Han, C. S., Munk, A. C., Chertkov, O., Meincke, L., Saunders, E., Walters, R. A., Huq, A., Nair, G. B., Colwell, R. R. (2009). Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae. Proc. Natl. Acad. Sci. USA 106: 15442-15447 [Abstract] [Full Text]  
  • Almagro-Moreno, S., Boyd, E. F. (2009). Sialic Acid Catabolism Confers a Competitive Advantage to Pathogenic Vibrio cholerae in the Mouse Intestine. Infect. Immun. 77: 3807-3816 [Abstract] [Full Text]  
  • Sikora, A. E., Beyhan, S., Bagdasarian, M., Yildiz, F. H., Sandkvist, M. (2009). Cell Envelope Perturbation Induces Oxidative Stress and Changes in Iron Homeostasis in Vibrio cholerae. J. Bacteriol. 191: 5398-5408 [Abstract] [Full Text]  
  • Grim, C. J., Zo, Y.-G., Hasan, N. A., Ali, A., Chowdhury, W. B., Islam, A., Rashid, M. H., Alam, M., Morris, J. G. Jr., Huq, A., Colwell, R. R. (2009). RNA Colony Blot Hybridization Method for Enumeration of Culturable Vibrio cholerae and Vibrio mimicus Bacteria. Appl. Environ. Microbiol. 75: 5439-5444 [Abstract] [Full Text]  
  • Bhowmick, T. S., Das, M., Ruppitsch, W., Stoeger, A., Pietzka, A. T., Allerberger, F., Rodrigues, D. P., Sarkar, B. L. (2009). Detection of virulence-associated and regulatory protein genes in association with phage typing of human Vibrio cholerae from several geographical regions of the world. J Med Microbiol 58: 1160-1167 [Abstract] [Full Text]  
  • Bandyopadhaya, A., Chaudhuri, K. (2009). Differential modulation of NF-{kappa}B-mediated pro-inflammatory response in human intestinal epithelial cells by cheY homologues of Vibrio cholerae. Innate Immunity 15: 131-142 [Abstract]  
  • Krebs, S. J., Kirn, T. J., Taylor, R. K. (2009). Genetic Mapping of Secretion and Functional Determinants of the Vibrio cholerae TcpF Colonization Factor. J. Bacteriol. 191: 3665-3676 [Abstract] [Full Text]  
  • Talyzina, N. M., Ingvarsson, P. K., Zhu, J., Wai, S. N., Andersson, A. (2009). Molecular Diversification in the Quorum-Sensing System of Vibrio cholerae: Role of Natural Selection in the Emergence of Pandemic Strains. Appl. Environ. Microbiol. 75: 3808-3812 [Abstract] [Full Text]  
  • Lybarger, S. R., Johnson, T. L., Gray, M. D., Sikora, A. E., Sandkvist, M. (2009). Docking and Assembly of the Type II Secretion Complex of Vibrio cholerae. J. Bacteriol. 191: 3149-3161 [Abstract] [Full Text]  
  • Nguyen, B. M., Lee, J. H., Cuong, N. T., Choi, S. Y., Hien, N. T., Anh, D. D., Lee, H. R., Ansaruzzaman, M., Endtz, H. P., Chun, J., Lopez, A. L., Czerkinsky, C., Clemens, J. D., Kim, D. W. (2009). Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008. J. Clin. Microbiol. 47: 1568-1571 [Abstract] [Full Text]  
  • Chatterjee, S., Ghosh, K., Raychoudhuri, A., Chowdhury, G., Bhattacharya, M. K., Mukhopadhyay, A. K., Ramamurthy, T., Bhattacharya, S. K., Klose, K. E., Nandy, R. K. (2009). Incidence, Virulence Factors, and Clonality among Clinical Strains of Non-O1, Non-O139 Vibrio cholerae Isolates from Hospitalized Diarrheal Patients in Kolkata, India. J. Clin. Microbiol. 47: 1087-1095 [Abstract] [Full Text]  
  • Pugliese, N., Maimone, F., Scrascia, M., Materu, S. F., Pazzani, C. (2009). SXT-related integrating conjugative element and IncC plasmids in Vibrio cholerae O1 strains in Eastern Africa. J Antimicrob Chemother 63: 438-442 [Abstract] [Full Text]  
  • Nusrin, S., Gil, A. I., Bhuiyan, N. A., Safa, A., Asakura, M., Lanata, C. F., Hall, E., Miranda, H., Huapaya, B., Vargas G., C., Luna, M. A., Sack, D. A., Yamasaki, S., Nair, G. B. (2009). Peruvian Vibrio cholerae O1 El Tor strains possess a distinct region in the Vibrio seventh pandemic island-II that differentiates them from the prototype seventh pandemic El Tor strains. J Med Microbiol 58: 342-354 [Abstract] [Full Text]  
  • Kumar, P., Jain, M., Goel, A. K., Bhadauria, S., Sharma, S. K., Kamboj, D. V., Singh, L., Ramamurthy, T., Nair, G. B. (2009). A large cholera outbreak due to a new cholera toxin variant of the Vibrio cholerae O1 El Tor biotype in Orissa, Eastern India. J Med Microbiol 58: 234-238 [Abstract] [Full Text]  
  • Chatterjee, S., Patra, T., Ghosh, K., Raychoudhuri, A., Pazhani, G. P., Das, M., Sarkar, B., Bhadra, R. K., Mukhopadhyay, A. K., Takeda, Y., Nair, G. B., Ramamurthy, T., Nandy, R. K. (2009). Vibrio cholerae O1 clinical strains isolated in 1992 in Kolkata with progenitor traits of the 2004 Mozambique variant. J Med Microbiol 58: 239-247 [Abstract] [Full Text]  
  • Hammer, B. K., Bassler, B. L. (2009). Distinct Sensory Pathways in Vibrio cholerae El Tor and Classical Biotypes Modulate Cyclic Dimeric GMP Levels To Control Biofilm Formation. J. Bacteriol. 191: 169-177 [Abstract] [Full Text]  
  • Schild, S., Nelson, E. J., Bishop, A. L., Camilli, A. (2009). Characterization of Vibrio cholerae Outer Membrane Vesicles as a Candidate Vaccine for Cholera. Infect. Immun. 77: 472-484 [Abstract] [Full Text]  
  • Safa, A., Bhuiyan, N. A., Murphy, D., Bates, J., Nusrin, S., Kong, R. Y. C., Chongsanguan, M., Chaicumpa, W., Nair, G. B. (2009). Multilocus genetic analysis reveals that the Australian strains of Vibrio cholerae O1 are similar to the pre-seventh pandemic strains of the El Tor biotype. J Med Microbiol 58: 105-111 [Abstract] [Full Text]  
  • Smith, A. M., Sooka, A., Ismail, H., Nadan, S., Crisp, N., Weenink, E., Keddy, K. H., for the Group for Enteric, Respiratory and Meninge, (2009). Analysis of Vibrio cholerae isolates from the Northern Cape province of South Africa. J Med Microbiol 58: 151-154 [Full Text]  
  • Harrison, L. M., Rallabhandi, P., Michalski, J., Zhou, X., Steyert, S. R., Vogel, S. N., Kaper, J. B. (2008). Vibrio cholerae Flagellins Induce Toll-Like Receptor 5-Mediated Interleukin-8 Production through Mitogen-Activated Protein Kinase and NF-{kappa}B Activation. Infect. Immun. 76: 5524-5534 [Abstract] [Full Text]  
  • Constantin de Magny, G., Murtugudde, R., Sapiano, M. R. P., Nizam, A., Brown, C. W., Busalacchi, A. J., Yunus, M., Nair, G. B., Gil, A. I., Lanata, C. F., Calkins, J., Manna, B., Rajendran, K., Bhattacharya, M. K., Huq, A., Sack, R. B., Colwell, R. R. (2008). From the Cover: Environmental signatures associated with cholera epidemics. Proc. Natl. Acad. Sci. USA 105: 17676-17681 [Abstract] [Full Text]  
  • Silva, A. J., Sultan, S. Z., Liang, W., Benitez, J. A. (2008). Role of the Histone-Like Nucleoid Structuring Protein in the Regulation of rpoS and RpoS-Dependent Genes in Vibrio cholerae. J. Bacteriol. 190: 7335-7345 [Abstract] [Full Text]  
  • Harris, A. M., Chowdhury, F., Begum, Y. A., Khan, A. I., Faruque, A. S. G., Svennerholm, A.-M., Harris, J. B., Ryan, E. T., Cravioto, A., Calderwood, S. B., Qadri, F. (2008). Shifting Prevalence of Major Diarrheal Pathogens in Patients Seeking Hospital Care during Floods in 1998, 2004, and 2007 in Dhaka, Bangladesh. Am J Trop Med Hyg 79: 708-714 [Abstract] [Full Text]  
  • Bhowmick, R., Ghosal, A., Das, B., Koley, H., Saha, D. R., Ganguly, S., Nandy, R. K., Bhadra, R. K., Chatterjee, N. S. (2008). Intestinal Adherence of Vibrio cholerae Involves a Coordinated Interaction between Colonization Factor GbpA and Mucin. Infect. Immun. 76: 4968-4977 [Abstract] [Full Text]  
  • Zahid, M. S. H., Udden, S. M. N., Faruque, A. S. G., Calderwood, S. B., Mekalanos, J. J., Faruque, S. M. (2008). Effect of Phage on the Infectivity of Vibrio cholerae and Emergence of Genetic Variants. Infect. Immun. 76: 5266-5273 [Abstract] [Full Text]  
  • Fong, J. C. N., Yildiz, F. H. (2008). Interplay between Cyclic AMP-Cyclic AMP Receptor Protein and Cyclic di-GMP Signaling in Vibrio cholerae Biofilm Formation. J. Bacteriol. 190: 6646-6659 [Abstract] [Full Text]  
  • Schild, S., Nelson, E. J., Camilli, A. (2008). Immunization with Vibrio cholerae Outer Membrane Vesicles Induces Protective Immunity in Mice. Infect. Immun. 76: 4554-4563 [Abstract] [Full Text]  
  • LaRocque, R. C., Krastins, B., Harris, J. B., Lebrun, L. M., Parker, K. C., Chase, M., Ryan, E. T., Qadri, F., Sarracino, D., Calderwood, S. B. (2008). Proteomic Analysis of Vibrio cholerae in Human Stool. Infect. Immun. 76: 4145-4151 [Abstract] [Full Text]  
  • Udden, S. M. N., Zahid, M. S. H., Biswas, K., Ahmad, Q. S., Cravioto, A., Nair, G. B., Mekalanos, J. J., Faruque, S. M. (2008). Acquisition of classical CTX prophage from Vibrio cholerae O141 by El Tor strains aided by lytic phages and chitin-induced competence. Proc. Natl. Acad. Sci. USA 105: 11951-11956 [Abstract] [Full Text]  
  • Khuntia, H. K., Pal, B. B., Chhotray, G. P. (2008). Quadruplex PCR for Simultaneous Detection of Serotype, Biotype, Toxigenic Potential, and Central Regulating Factor of Vibrio cholerae. J. Clin. Microbiol. 46: 2399-2401 [Abstract] [Full Text]  
  • Stonehouse, E., Kovacikova, G., Taylor, R. K., Skorupski, K. (2008). Integration Host Factor Positively Regulates Virulence Gene Expression in Vibrio cholerae. J. Bacteriol. 190: 4736-4748 [Abstract] [Full Text]  
  • Jeong, H. G., Choi, S. H. (2008). Evidence that AphB, Essential for the Virulence of Vibrio vulnificus, Is a Global Regulator. J. Bacteriol. 190: 3768-3773 [Abstract] [Full Text]  
  • Jorgensen, R., Purdy, A. E., Fieldhouse, R. J., Kimber, M. S., Bartlett, D. H., Merrill, A. R. (2008). Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae. J. Biol. Chem. 283: 10671-10678 [Abstract] [Full Text]  
  • Jain, D., Prasad, K. N., Sinha, S., Husain, N. (2008). Differences in virulence attributes between cytolethal distending toxin positive and negative Campylobacter jejuni strains. J Med Microbiol 57: 267-272 [Abstract] [Full Text]  
  • Kudryashov, D. S., Cordero, C. L., Reisler, E., Satchell, K. J. F. (2008). Characterization of the Enzymatic Activity of the Actin Cross-linking Domain from the Vibrio cholerae MARTXVc Toxin. J. Biol. Chem. 283: 445-452 [Abstract] [Full Text]  
  • Johnson, T. L., Scott, M. E., Sandkvist, M. (2007). Mapping Critical Interactive Sites within the Periplasmic Domain of the Vibrio cholerae Type II Secretion Protein EpsM. J. Bacteriol. 189: 9082-9089 [Abstract] [Full Text]  
  • Sikora, A. E., Lybarger, S. R., Sandkvist, M. (2007). Compromised Outer Membrane Integrity in Vibrio cholerae Type II Secretion Mutants. J. Bacteriol. 189: 8484-8495 [Abstract] [Full Text]  
  • Kim, J.-S., Diebold, B. A., Babior, B. M., Knaus, U. G., Bokoch, G. M. (2007). Regulation of Nox1 Activity via Protein Kinase A-mediated Phosphorylation of NoxA1 and 14-3-3 Binding. J. Biol. Chem. 282: 34787-34800 [Abstract] [Full Text]  
  • Makita, N., Sato, J., Rondard, P., Fukamachi, H., Yuasa, Y., Aldred, M. A., Hashimoto, M., Fujita, T., Iiri, T. (2007). Human Gs{alpha} mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle. Proc. Natl. Acad. Sci. USA 104: 17424-17429 [Abstract] [Full Text]  
  • Olivier, V., Haines, G. K. III, Tan, Y., Satchell, K. J. F. (2007). Hemolysin and the Multifunctional Autoprocessing RTX Toxin Are Virulence Factors during Intestinal Infection of Mice with Vibrio cholerae El Tor O1 Strains. Infect. Immun. 75: 5035-5042 [Abstract] [Full Text]  
  • Olivier, V., Salzman, N. H., Satchell, K. J. F. (2007). Prolonged Colonization of Mice by Vibrio cholerae El Tor O1 Depends on Accessory Toxins. Infect. Immun. 75: 5043-5051 [Abstract] [Full Text]  
  • Cordero, C. L., Sozhamannan, S., Satchell, K. J. F. (2007). RTX Toxin Actin Cross-Linking Activity in Clinical and Environmental Isolates of Vibrio cholerae. J. Clin. Microbiol. 45: 2289-2292 [Abstract] [Full Text]  
  • Pang, B., Yan, M., Cui, Z., Ye, X., Diao, B., Ren, Y., Gao, S., Zhang, L., Kan, B. (2007). Genetic Diversity of Toxigenic and Nontoxigenic Vibrio cholerae Serogroups O1 and O139 Revealed by Array-Based Comparative Genomic Hybridization. J. Bacteriol. 189: 4837-4849 [Abstract] [Full Text]  
  • Tripathi, S. A., Taylor, R. K. (2007). Membrane Association and Multimerization of TcpT, the Cognate ATPase Ortholog of the Vibrio cholerae Toxin-Coregulated-Pilus Biogenesis Apparatus. J. Bacteriol. 189: 4401-4409 [Abstract] [Full Text]  
  • Keymer, D. P., Miller, M. C., Schoolnik, G. K., Boehm, A. B. (2007). Genomic and Phenotypic Diversity of Coastal Vibrio cholerae Strains Is Linked to Environmental Factors. Appl. Environ. Microbiol. 73: 3705-3714 [Abstract] [Full Text]  
  • Labbate, M., Boucher, Y., Joss, M. J., Michael, C. A., Gillings, M. R., Stokes, H. W. (2007). Use of chromosomal integron arrays as a phylogenetic typing system for Vibrio cholerae pandemic strains. Microbiology 153: 1488-1498 [Abstract] [Full Text]  
  • Chatterjee, A., Dutta, P. K., Chowdhury, R. (2007). Effect of Fatty Acids and Cholesterol Present in Bile on Expression of Virulence Factors and Motility of Vibrio cholerae. Infect. Immun. 75: 1946-1953 [Abstract] [Full Text]  
  • Faruque, S. M., Tam, V. C., Chowdhury, N., Diraphat, P., Dziejman, M., Heidelberg, J. F., Clemens, J. D., Mekalanos, J. J., Nair, G. B. (2007). Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage. Proc. Natl. Acad. Sci. USA 104: 5151-5156 [Abstract] [Full Text]  
  • Fong, J. C. N., Yildiz, F. H. (2007). The rbmBCDEF Gene Cluster Modulates Development of Rugose Colony Morphology and Biofilm Formation in Vibrio cholerae. J. Bacteriol. 189: 2319-2330 [Abstract] [Full Text]  
  • Danin-Poleg, Y., Cohen, L. A., Gancz, H., Broza, Y. Y., Goldshmidt, H., Malul, E., Valinsky, L., Lerner, L., Broza, M., Kashi, Y. (2007). Vibrio cholerae Strain Typing and Phylogeny Study Based on Simple Sequence Repeats. J. Clin. Microbiol. 45: 736-746 [Abstract] [Full Text]  
  • Fykse, E. M., Skogan, G., Davies, W., Olsen, J. S., Blatny, J. M. (2007). Detection of Vibrio cholerae by Real-Time Nucleic Acid Sequence-Based Amplification. Appl. Environ. Microbiol. 73: 1457-1466 [Abstract] [Full Text]  
  • Gutierrez, M. G., Saka, H. A., Chinen, I., Zoppino, F. C. M., Yoshimori, T., Bocco, J. L., Colombo, M. I. (2007). Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc. Natl. Acad. Sci. USA 104: 1829-1834 [Abstract] [Full Text]  
  • Beyhan, S., Bilecen, K., Salama, S. R., Casper-Lindley, C., Yildiz, F. H. (2007). Regulation of Rugosity and Biofilm Formation in Vibrio cholerae: Comparison of VpsT and VpsR Regulons and Epistasis Analysis of vpsT, vpsR, and hapR. J. Bacteriol. 189: 388-402 [Abstract] [Full Text]  
  • Maiti, D., Das, B., Saha, A., Nandy, R. K., Nair, G. B., Bhadra, R. K. (2006). Genetic organization of pre-CTX and CTX prophages in the genome of an environmental Vibrio cholerae non-O1, non-O139 strain. Microbiology 152: 3633-3641 [Abstract] [Full Text]  
  • Yoon, S. S., Mekalanos, J. J. (2006). 2,3-Butanediol Synthesis and the Emergence of the Vibrio cholerae El Tor Biotype. Infect. Immun. 74: 6547-6556 [Abstract] [Full Text]  
  • Xicohtencatl-Cortes, J., Lyons, S., Chaparro, A. P., Hernandez, D. R., Saldana, Z., Ledesma, M. A., Rendon, M. A., Gewirtz, A. T., Klose, K. E., Giron, J. A. (2006). Identification of Proinflammatory Flagellin Proteins in Supernatants of Vibrio cholerae O1 by Proteomics Analysis. Mol. Cell. Proteomics 5: 2374-2383 [Abstract] [Full Text]  
  • GRIFFITH, D. C., KELLY-HOPE, L. A., MILLER, M. A. (2006). REVIEW OF REPORTED CHOLERA OUTBREAKS WORLDWIDE, 1995-2005. Am J Trop Med Hyg 75: 973-977 [Abstract] [Full Text]  
  • Nair, G. B., Safa, A., Bhuiyan, N. A., Nusrin, S., Murphy, D., Nicol, C., Valcanis, M., Iddings, S., Kubuabola, I., Vally, H. (2006). Isolation of Vibrio cholerae O1 strains similar to pre-seventh pandemic El Tor strains during an outbreak of gastrointestinal disease in an island resort in Fiji.. J Med Microbiol 55: 1559-1562 [Abstract] [Full Text]  
  • Safa, A., Bhuyian, N. A., Nusrin, S., Ansaruzzaman, M., Alam, M., Hamabata, T., Takeda, Y., Sack, D. A., Nair, G. B. (2006). Genetic characteristics of Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes.. J Med Microbiol 55: 1563-1569 [Abstract] [Full Text]  
  • Cordero, C. L., Kudryashov, D. S., Reisler, E., Satchell, K. J. F. (2006). The Actin Cross-linking Domain of the Vibrio cholerae RTX Toxin Directly Catalyzes the Covalent Cross-linking of Actin. J. Biol. Chem. 281: 32366-32374 [Abstract] [Full Text]  
  • RICHARDS, G. P., WATSON, M. A. (2006). A simple fluorogenic method to detect Vibrio cholerae and Aeromonas hydrophila in well water for areas impacted by catastrophic disasters.. Am J Trop Med Hyg 75: 516-521 [Abstract] [Full Text]  
  • Vaitkevicius, K., Lindmark, B., Ou, G., Song, T., Toma, C., Iwanaga, M., Zhu, J., Andersson, A., Hammarstrom, M.-L., Tuck, S., Wai, S. N. (2006). A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing. Proc. Natl. Acad. Sci. USA 103: 9280-9285 [Abstract] [Full Text]  
  • Beyhan, S., Tischler, A. D., Camilli, A., Yildiz, F. H. (2006). Differences in Gene Expression between the Classical and El Tor Biotypes of Vibrio cholerae O1.. Infect. Immun. 74: 3633-3642 [Abstract] [Full Text]  
  • Ghosh, A., Paul, K., Chowdhury, R. (2006). Role of the Histone-Like Nucleoid Structuring Protein in Colonization, Motility, and Bile-Dependent Repression of Virulence Gene Expression in Vibrio cholerae.. Infect. Immun. 74: 3060-3064 [Abstract] [Full Text]  
  • Faruque, S. M., Biswas, K., Udden, S. M. N., Ahmad, Q. S., Sack, D. A., Nair, G. B., Mekalanos, J. J. (2006). Transmissibility of cholera: In vivo-formed biofilms and their relationship to infectivity and persistence in the environment. Proc. Natl. Acad. Sci. USA 103: 6350-6355 [Abstract] [Full Text]  
  • Alam, M., Sultana, M., Nair, G. B., Sack, R. B., Sack, D. A., Siddique, A. K., Ali, A., Huq, A., Colwell, R. R. (2006). Toxigenic Vibrio cholerae in the Aquatic Environment of Mathbaria, Bangladesh. Appl. Environ. Microbiol. 72: 2849-2855 [Abstract] [Full Text]  
  • Teter, K., Jobling, M. G., Sentz, D., Holmes, R. K. (2006). The Cholera Toxin A13 Subdomain Is Essential for Interaction with ADP-Ribosylation Factor 6 and Full Toxic Activity but Is Not Required for Translocation from the Endoplasmic Reticulum to the Cytosol. Infect. Immun. 74: 2259-2267 [Abstract] [Full Text]  
  • Banerjee, S., Chowdhury, R. (2006). An orphan DNA (cytosine-5-)-methyltransferase in Vibrio cholerae.. Microbiology 152: 1055-1062 [Abstract] [Full Text]  
  • Fong, J. C. N., Karplus, K., Schoolnik, G. K., Yildiz, F. H. (2006). Identification and Characterization of RbmA, a Novel Protein Required for the Development of Rugose Colony Morphology and Biofilm Structure in Vibrio cholerae. J. Bacteriol. 188: 1049-1059 [Abstract] [Full Text]  
  • Lee, J. H., Han, K. H., Choi, S. Y., Lucas, M. E. S., Mondlane, C., Ansaruzzaman, M., Nair, G. B., Sack, D. A., von Seidlein, L., Clemens, J. D., Song, M., Chun, J., The Mozambique Cholera Vaccine Demonstration Proje, , Kim, D. W. (2006). Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage. J Med Microbiol 55: 165-170 [Abstract] [Full Text]  
  • Harris, J. B., Khan, A. I., LaRocque, R. C., Dorer, D. J., Chowdhury, F., Faruque, A. S. G., Sack, D. A., Ryan, E. T., Qadri, F., Calderwood, S. B. (2005). Blood Group, Immunity, and Risk of Infection with Vibrio cholerae in an Area of Endemicity. Infect. Immun. 73: 7422-7427 [Abstract] [Full Text]  
  • Qadri, F., Svennerholm, A.-M., Shamsuzzaman, S., Bhuiyan, T. R., Harris, J. B., Ghosh, A. N., Nair, G. B., Weintraub, A., Faruque, S. M., Ryan, E. T., Sack, D. A., Calderwood, S. B. (2005). Reduction in Capsular Content and Enhanced Bacterial Susceptibility to Serum Killing of Vibrio cholerae O139 Associated with the 2002 Cholera Epidemic in Bangladesh. Infect. Immun. 73: 6577-6583 [Abstract] [Full Text]  
  • Alam, A., LaRocque, R. C., Harris, J. B., Vanderspurt, C., Ryan, E. T., Qadri, F., Calderwood, S. B. (2005). Hyperinfectivity of Human-Passaged Vibrio cholerae Can Be Modeled by Growth in the Infant Mouse. Infect. Immun. 73: 6674-6679 [Abstract] [Full Text]  
  • Tischler, A. D., Camilli, A. (2005). Cyclic Diguanylate Regulates Vibrio cholerae Virulence Gene Expression. Infect. Immun. 73: 5873-5882 [Abstract] [Full Text]  
  • Haines, G. K. III, Sayed, B. A., Rohrer, M. S., Olivier, V., Satchell, K. J. F. (2005). Role of Toll-Like Receptor 4 in the Proinflammatory Response to Vibrio cholerae O1 El Tor Strains Deficient in Production of Cholera Toxin and Accessory Toxins. Infect. Immun. 73: 6157-6164 [Abstract] [Full Text]  
  • Nandi, B., Nandy, R. K., Sarkar, A., Ghose, A. C. (2005). Structural features, properties and regulation of the outer-membrane protein W (OmpW) of Vibrio cholerae. Microbiology 151: 2975-2986 [Abstract] [Full Text]  
  • Gancz, H., Niderman-Meyer, O., Broza, M., Kashi, Y., Shimoni, E. (2005). Adhesion of Vibrio cholerae to Granular Starches. Appl. Environ. Microbiol. 71: 4850-4855 [Abstract] [Full Text]  
  • Kirn, T. J., Taylor, R. K. (2005). TcpF Is a Soluble Colonization Factor and Protective Antigen Secreted by El Tor and Classical O1 and O139 Vibrio cholerae Serogroups. Infect. Immun. 73: 4461-4470 [Abstract] [Full Text]  
  • LaRocque, R. C., Harris, J. B., Dziejman, M., Li, X., Khan, A. I., Faruque, A. S. G., Faruque, S. M., Nair, G. B., Ryan, E. T., Qadri, F., Mekalanos, J. J., Calderwood, S. B. (2005). Transcriptional Profiling of Vibrio cholerae Recovered Directly from Patient Specimens during Early and Late Stages of Human Infection. Infect. Immun. 73: 4488-4493 [Abstract] [Full Text]  
  • Faruque, S. M., Islam, M. J., Ahmad, Q. S., Faruque, A. S. G., Sack, D. A., Nair, G. B., Mekalanos, J. J. (2005). Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phage. Proc. Natl. Acad. Sci. USA 102: 6119-6124 [Abstract] [Full Text]  
  • De Silva, R. S., Kovacikova, G., Lin, W., Taylor, R. K., Skorupski, K., Kull, F. J. (2005). Crystal Structure of the Virulence Gene Activator AphA from Vibrio cholerae Reveals It Is a Novel Member of the Winged Helix Transcription Factor Superfamily. J. Biol. Chem. 280: 13779-13783 [Abstract] [Full Text]  
  • Bose, N., Taylor, R. K. (2005). Identification of a TcpC-TcpQ Outer Membrane Complex Involved in the Biogenesis of the Toxin-Coregulated Pilus of Vibrio cholerae. J. Bacteriol. 187: 2225-2232 [Abstract] [Full Text]  
  • Safa, A., Bhuiyan, N. A., Alam, M., Sack, D. A., Nair, G. B. (2005). Genomic Relatedness of the New Matlab Variants of Vibrio cholerae O1 to the Classical and El Tor Biotypes as Determined by Pulsed-Field Gel Electrophoresis. J. Clin. Microbiol. 43: 1401-1404 [Abstract] [Full Text]  
  • Ali, A., Morris, J. G. Jr., Johnson, J. A. (2005). Sugars Inhibit Expression of the Rugose Phenotype of Vibrio cholerae. J. Clin. Microbiol. 43: 1426-1429 [Abstract] [Full Text]  
  • O'Shea, Y. A., Finnan, S., Reen, F. J., Morrissey, J. P., O'Gara, F., Boyd, E. F. (2004). The Vibrio seventh pandemic island-II is a 26{middle dot}9 kb genomic island present in Vibrio cholerae El Tor and O139 serogroup isolates that shows homology to a 43{middle dot}4 kb genomic island in V. vulnificus. Microbiology 150: 4053-4063 [Abstract] [Full Text]  
  • SUGUNAN, A. P., GHOSH, A. R., ROY, S., GUPTE, M. D., SEHGAL, S. C. (2004). A CHOLERA EPIDEMIC AMONG THE NICOBARESE TRIBE OF NANCOWRY, ANDAMAN, AND NICOBAR, INDIA. Am J Trop Med Hyg 71: 822-827 [Abstract] [Full Text]  
  • O'Shea, Y. A., Reen, F. J., Quirke, A. M., Boyd, E. F. (2004). Evolutionary Genetic Analysis of the Emergence of Epidemic Vibrio cholerae Isolates on the Basis of Comparative Nucleotide Sequence Analysis and Multilocus Virulence Gene Profiles. J. Clin. Microbiol. 42: 4657-4671 [Abstract] [Full Text]  
  • Paul, K., Ghosh, A., Sengupta, N., Chowdhury, R. (2004). Competitive Growth Advantage of Nontoxigenic Mutants in the Stationary Phase in Archival Cultures of Pathogenic Vibrio cholerae Strains. Infect. Immun. 72: 5478-5482 [Abstract] [Full Text]  
  • Krishnan, H. H., Ghosh, A., Paul, K., Chowdhury, R. (2004). Effect of Anaerobiosis on Expression of Virulence Factors in Vibrio cholerae. Infect. Immun. 72: 3961-3967 [Abstract] [Full Text]  
  • Stokes, N. R., Zhou, X., Meltzer, S. J., Kaper, J. B. (2004). Transcriptional Responses of Intestinal Epithelial Cells to Infection with Vibrio cholerae. Infect. Immun. 72: 4240-4248 [Abstract] [Full Text]  
  • Sheahan, K.-L., Cordero, C. L., Fullner Satchell, K. J. (2004). Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin. Proc. Natl. Acad. Sci. USA 101: 9798-9803 [Abstract] [Full Text]  
  • Faruque, S. M., Chowdhury, N., Kamruzzaman, M., Dziejman, M., Rahman, M. H., Sack, D. A., Nair, G. B., Mekalanos, J. J. (2004). Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area. Proc. Natl. Acad. Sci. USA 101: 2123-2128 [Abstract] [Full Text]  
  • O'Hara, C. M., Sowers, E. G., Bopp, C. A., Duda, S. B., Strockbine, N. A. (2003). Accuracy of Six Commercially Available Systems for Identification of Members of the Family Vibrionaceae. J. Clin. Microbiol. 41: 5654-5659 [Abstract] [Full Text]  
  • Datta, P. P., Bhadra, R. K. (2003). Cold Shock Response and Major Cold Shock Proteins of Vibrio cholerae. Appl. Environ. Microbiol. 69: 6361-6369 [Abstract] [Full Text]  
  • Mourino-Perez, R. R., Worden, A. Z., Azam, F. (2003). Growth of Vibrio cholerae O1 in Red Tide Waters off California. Appl. Environ. Microbiol. 69: 6923-6931 [Abstract] [Full Text]  
  • Sengupta, N., Paul, K., Chowdhury, R. (2003). The Global Regulator ArcA Modulates Expression of Virulence Factors in Vibrio cholerae. Infect. Immun. 71: 5583-5589 [Abstract] [Full Text]  
  • Campos, J., Martinez, E., Suzarte, E., Rodriguez, B. L., Marrero, K., Silva, Y., Ledon, T., del Sol, R., Fando, R. (2003). VGJ{phi}, a Novel Filamentous Phage of Vibrio cholerae, Integrates into the Same Chromosomal Site as CTX{phi}. J. Bacteriol. 185: 5685-5696 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»