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Review

Bacterial Contamination of Blood Components

Mark E. Brecher, Shauna N. Hay
Mark E. Brecher
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina
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  • For correspondence: Brecher@med.unc.edu
Shauna N. Hay
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina
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DOI: 10.1128/CMR.18.1.195-204.2005
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SUMMARY

SUMMARY Blood for transfusion is a potential source of infection by a variety of known and unknown transmissible agents. Over the last 20 years, astounding reductions in the risk of viral infection via allogeneic blood have been achieved. As a result of this success, bacterial contamination of blood products has emerged as the greatest residual source of transfusion-transmitted disease. This paper summarizes the current status of detection, prevention, and elimination of bacteria in blood products for transfusion.

  • Copyright © 2005 American Society for Microbiology
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Bacterial Contamination of Blood Components
Mark E. Brecher, Shauna N. Hay
Clinical Microbiology Reviews Jan 2005, 18 (1) 195-204; DOI: 10.1128/CMR.18.1.195-204.2005

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Bacterial Contamination of Blood Components
Mark E. Brecher, Shauna N. Hay
Clinical Microbiology Reviews Jan 2005, 18 (1) 195-204; DOI: 10.1128/CMR.18.1.195-204.2005
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  • Top
  • Article
    • SUMMARY
    • INTRODUCTION
    • TRANSFUSION-TRANSMITTED BACTERIAL INFECTION OF RED CELLS
    • TRANSFUSION-TRANSMITTED BACTERIAL INFECTION OF PLATELETS
    • TRANSFUSION-TRANSMITTED BACTERIAL INFECTION OF PLASMA AND CRYOPRECIPITATE
    • SOURCES OF CONTAMINATION
    • METHODS TO REDUCE THE RISK OF POST-TRANSFUSION SEPSIS
    • THE PROSPECT OF SEVEN-DAY STORAGE WITH DETECTION
    • CONCLUSIONS
    • REFERENCES
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KEYWORDS

Blood Platelets
Equipment Contamination
Erythrocyte Transfusion
Erythrocytes
Platelet Transfusion

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