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Review

Approved Antiviral Drugs over the Past 50 Years

Erik De Clercq, Guangdi Li
Erik De Clercq
aKU Leuven-University of Leuven, Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium
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  • For correspondence: erik.declercq@kuleuven.be liguangdi.research@gmail.com
Guangdi Li
aKU Leuven-University of Leuven, Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium
bDepartment of Metabolism and Endocrinology, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
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  • For correspondence: erik.declercq@kuleuven.be liguangdi.research@gmail.com
DOI: 10.1128/CMR.00102-15
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Article Information

DOI 
https://doi.org/10.1128/CMR.00102-15
PubMed 
27281742

Published By 
American Society for Microbiology Journals
History 
  • Published online June 8, 2016.

Copyright & Usage 
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Author Information

  1. Erik De Clercqa⇑ and
  2. Guangdi Lia,b⇑
  1. aKU Leuven-University of Leuven, Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium
  2. bDepartment of Metabolism and Endocrinology, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
  • Address correspondence to Erik De Clercq, erik.declercq{at}kuleuven.be, or Guangdi Li, liguangdi.research{at}gmail.com.
  • Citation De Clercq E, Li G. 2016. Approved antiviral drugs over the past 50 years. Clin Microbiol Rev 29:695–747. doi:10.1128/CMR.00102-15.

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Approved Antiviral Drugs over the Past 50 Years
Erik De Clercq, Guangdi Li
Clinical Microbiology Reviews Jun 2016, 29 (3) 695-747; DOI: 10.1128/CMR.00102-15

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Approved Antiviral Drugs over the Past 50 Years
Erik De Clercq, Guangdi Li
Clinical Microbiology Reviews Jun 2016, 29 (3) 695-747; DOI: 10.1128/CMR.00102-15
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  • Top
  • Article
    • SUMMARY
    • INTRODUCTION
    • OVERVIEW OF NINE HUMAN VIRUSES
    • 5-SUBSTITUTED 2′-DEOXYURIDINE ANALOGUES
    • NUCLEOSIDE ANALOGUES
    • PYROPHOSPHATE ANALOGUES
    • NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
    • NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
    • PROTEASE INHIBITORS
    • INTEGRASE INHIBITORS
    • ENTRY INHIBITORS
    • ACYCLIC GUANOSINE ANALOGUES
    • ACYCLIC NUCLEOSIDE PHOSPHONATE ANALOGUES
    • HCV NS5A/NS5B INHIBITORS
    • INFLUENZA VIRUS INHIBITORS
    • INTERFERONS, IMMUNOSTIMULATORS, OLIGONUCLEOTIDES, AND ANTIMITOTIC INHIBITORS
    • FORTHCOMING ANTIVIRAL INHIBITORS
    • ANTIVIRAL STRATEGIES AGAINST CURRENT AND EMERGING INFECTIOUS DISEASES
    • CONCLUSIONS AND FUTURE PERSPECTIVES
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
    • Author Bios
  • Figures & Data
  • Info & Metrics
  • PDF

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