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Review

Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies

Hamed Haddad Kashani, Mathias Schmelcher, Hamed Sabzalipoor, Elahe Seyed Hosseini, Rezvan Moniri
Hamed Haddad Kashani
aAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran
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Mathias Schmelcher
bInstitute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland
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Hamed Sabzalipoor
cDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
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Elahe Seyed Hosseini
aAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran
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Rezvan Moniri
aAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran
dDepartment of Immunology and Microbiology, Kashan University of Medical Sciences, Kashan, Iran
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DOI: 10.1128/CMR.00071-17
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Article Information

DOI 
https://doi.org/10.1128/CMR.00071-17
PubMed 
29187396

Published By 
American Society for Microbiology Journals
History 
  • Published online November 29, 2017.

Copyright & Usage 
Copyright © 2017 American Society for Microbiology. All Rights Reserved.

Author Information

  1. Hamed Haddad Kashania,
  2. Mathias Schmelcherb,
  3. Hamed Sabzalipoorc,
  4. Elahe Seyed Hosseinia and
  5. Rezvan Moniria,d
  1. aAnatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran
  2. bInstitute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland
  3. cDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
  4. dDepartment of Immunology and Microbiology, Kashan University of Medical Sciences, Kashan, Iran
  • Address correspondence to Mathias Schmelcher, mathias.schmelcher{at}hest.ethz.ch, or Rezvan Moniri, hamedir2010{at}gmail.com.
  • Citation Haddad Kashani H, Schmelcher M, Sabzalipoor H, Seyed Hosseini E, Moniri R. 2018. Recombinant endolysins as potential therapeutics against antibiotic-resistant Staphylococcus aureus: current status of research and novel delivery strategies. Clin Microbiol Rev 31:e00071-17. https://doi.org/10.1128/CMR.00071-17.

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Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies
Hamed Haddad Kashani, Mathias Schmelcher, Hamed Sabzalipoor, Elahe Seyed Hosseini, Rezvan Moniri
Clinical Microbiology Reviews Nov 2017, 31 (1) e00071-17; DOI: 10.1128/CMR.00071-17

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Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies
Hamed Haddad Kashani, Mathias Schmelcher, Hamed Sabzalipoor, Elahe Seyed Hosseini, Rezvan Moniri
Clinical Microbiology Reviews Nov 2017, 31 (1) e00071-17; DOI: 10.1128/CMR.00071-17
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  • Top
  • Article
    • SUMMARY
    • INTRODUCTION
    • ANTIBIOTIC RESISTANCE IN STAPHYLOCOCCUS AUREUS
    • BACTERIOPHAGE
    • ENDOLYSINS
    • LysK AND ITS HOMOLOGUES
    • ENDOLYSIN PRODUCTION IN LACTIC ACID BACTERIA FOR FOOD SAFETY APPLICATIONS
    • NANOTECHNOLOGY AS A NEW STRATEGY FOR ENDOLYSIN DELIVERY
    • CONCLUDING REMARKS
    • ACKNOWLEDGMENTS
    • REFERENCES
    • Author Bios
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

antibiotic resistance
endolysin
Staphylococcus aureus
probiotic bacteria
nanoparticles
infectious diseases

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