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Review

Human Herpesviruses 6A and 6B in Brain Diseases: Association versus Causation

Anthony L. Komaroff, Philip E. Pellett, Steven Jacobson
Anthony L. Komaroff
aDepartment of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
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  • ORCID record for Anthony L. Komaroff
Philip E. Pellett
bDepartment of Microbiology and Immunology, Wayne State University School of Medicine, Detroit, Michigan, USA
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Steven Jacobson
cVirology/Immunology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
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DOI: 10.1128/CMR.00143-20
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Article Information

DOI 
https://doi.org/10.1128/CMR.00143-20
PubMed 
33177186

Published By 
American Society for Microbiology Journals
History 
  • Published online November 11, 2020.

Copyright & Usage 
Copyright © 2020 American Society for Microbiology. All Rights Reserved.

Author Information

  1. Anthony L. Komaroffa,
  2. Philip E. Pellettb and
  3. Steven Jacobsonc
  1. aDepartment of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
  2. bDepartment of Microbiology and Immunology, Wayne State University School of Medicine, Detroit, Michigan, USA
  3. cVirology/Immunology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
  • Address correspondence to Anthony L. Komaroff, komaroff{at}hms.harvard.edu.
  • Citation Komaroff AL, Pellett PE, Jacobson S. 2021. Human herpesviruses 6A and 6B in brain diseases: association versus causation. Clin Microbiol Rev 34:e00143-20. https://doi.org/10.1128/CMR.00143-20.

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Human Herpesviruses 6A and 6B in Brain Diseases: Association versus Causation
Anthony L. Komaroff, Philip E. Pellett, Steven Jacobson
Clinical Microbiology Reviews Nov 2020, 34 (1) e00143-20; DOI: 10.1128/CMR.00143-20

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Human Herpesviruses 6A and 6B in Brain Diseases: Association versus Causation
Anthony L. Komaroff, Philip E. Pellett, Steven Jacobson
Clinical Microbiology Reviews Nov 2020, 34 (1) e00143-20; DOI: 10.1128/CMR.00143-20
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  • Article
    • SUMMARY
    • INTRODUCTION
    • BIOLOGY OF HHV-6A/B
    • EVIDENCE REQUIRED TO LINK HHV-6A/B WITH A DISEASE
    • HHV-6A/B IN FEBRILE SEIZURES AND FEBRILE STATUS EPILEPTICUS
    • HHV-6A/B IN MESIAL TEMPORAL LOBE EPILEPSY
    • HHV-6A/B IN MULTIPLE SCLEROSIS
    • HHV-6A/B IN ALZHEIMER’S DISEASE
    • CONCLUDING REMARKS
    • ACKNOWLEDGMENTS
    • REFERENCES
    • Author Bios
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

Alzheimer's disease
febrile seizures
febrile status epilepticus
mesial temporal lobe epilepsy
Multiple Sclerosis
human herpesvirus 6A
human herpesvirus 6B

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