Table 3

Main characteristics of currently available tick-borne Rickettsia genomesa

SpeciesStrainRickettsiosisChromosome size (kb)No. of ORFsG+C content (%)Noncoding DNA (%)No. of plasmids (size [kb])GenBank accession no.
R. africae ESF-5African tick bite fever1,278,5401,26032.4281 (12.4)CP001612
R. australis PhillipsQueensland tick typhus1,297,3901,11031.7262 (26.6 and 30.1)AKVZ00000000
CutlackQueensland tick typhus1,296,6701,29732.3NA1 (26.6)CP003338
R. bellii OSU 85-389Unknown pathogenesis1,528,9801,47032200CP000849
RML369-C 1,522,0761,42931.714.80CP000087
R. canadensis McKielUnknown pathogenesis1,159,7221,12931.1260CP000409
CA410Unknown pathogenesis1,150,2281,05231NA0CP003304
R. conorii subsp. conorii Malish SevenMediterranean spotted fever1,268,7551,37432.4190AE006914
R. conorii subsp. indica ITTRIndian tick typhus1,249,4821,15732.519.10AJHC00000000
R. conorii subsp. caspia A-167Astrakhan fever1,260,3311,2103318.80AJUR00000000
R. conorii subsp. israelensis ISTTCDC1Israeli spotted fever1,252,8151,1643220.00AJVP00000000
R. heilongjiangensis 054Far-Eastern tick-borne rickettsiosis1,278,4711,29732.3170CP002912
R. helvetica C9P9Unnamed rickettsiosis1,369,8271,13532.215.91 (47.1)CM001467
R. honei RBFlinders Island spotted fever1,268,7581,28432.4190AJTT00000000
R. japonica YHOriental spotted fever1,331,7431,23932.7281 (19.8)AMRT00000000
YHOriental spotted fever1,283,0871,01032.4NA0AP011533
R. massiliae Mtu5Unnamed rickettsiosis1,360,8981,43632.5311 (15.2)CP000683
AZT80Unknown pathogenesis1,263,7191,24332.6NA1 (15.0)CP003319
R. montanensis OSU 85-930Unknown pathogenesis1,279,7981,25432.6NA0CP003340
R. parkeri Portsmouth R. parkeri rickettsiosis1,300,3861,35432.4NA0CP003341
R. peacockii RusticUnknown pathogenesis1,288,49298433NA1 (26.4)CP001227
R. philipii 364DUnnamed rickettsiosis1,287,7401,38032.5NA0CP003308
R. raoultii RpA4SENLAT1,275,0891,35532.515.43 (20.8, 34.5, and 83.2)CP002428
R. rhipicephali 3-7-female6-CWPPUnknown pathogenesis1,290,3681,30232.4NA1 (15.0)CP003342
R. rickettsii Sheila SmithRocky Mountain spotted fever1,257,7101,38232.4240NC_009882
IowaAvirulent1,268,1751,42132.4NA0NC_010263
ArizonaRocky Mountain spotted fever1,267,1971,38032.4NA0CP003307
BrazilRocky Mountain spotted fever1,255,6811,36932.5NA0CP003305
ColombiaRocky Mountain spotted fever1,270,0831,38732.5NA0CP003306
Hlp#2Unknown pathogenicity1,270,7511,34532.5NA0CP003311
R. sibirica subsp. sibirica BJ-90Siberian tick typhus1,254,0131,18232.517.50AHIZ00000000
246 1,250,0211,15132.517.30AABW00000000
R. sibirica subsp. mongolitimonae HA-91Lymphangitis-associated rickettsiosis1,252,3371,13832.418.50AHZB00000000
R. slovaca 13-BTick-borne lymphadenitis1,275,0891,32332.518.70CP002428
D-CWPPTick-borne lymphadenitis1,275,7201,38632.5NA0CP003375
Rickettsia endosymbiont of Ixodes scapularis Unknown pathogenesis1,821,7092,05931224 (33.9, 49.8, 55.1, and 66.8)NZ_ACLC00000000
  • a ORFs, open reading frames; NA, not applicable.