Percentages of clinical CoNS isolates categorized as antibiotic resistant toward various antibiotic agents

ParameterValue or description in study for given species a
Hellmark et al., 2009 (499) Mendes et al., 2010 (497) b Putnam et al., 2010 (543) Kresken et al., 2011 (75) c Mendes et al., 2012 (64) Gordon et al., 2012 (65) d Barros et al., 2012 (573) Flamm et al., 2013 (534) e Zhanel et al., 2013 (496)
S. epidermidisMS-CoNSMR-CoNSCoNSS. epidermidisS. haemolyticusS. epidermidisS. epidermidisS. haemolyticusMS-CoNSMR-CoNSMS-SEMR-SE
Study design parameters
    No. of isolates334201,3882,510148102711006427848347585
    SourcePJIDiverseDiverseMainly BSI, also cSSSIDiverseDiverseMainly BSIDiverseMainly BSIDiverseDiverseDiverseDiverse
% Resistant isolates
    TeicoplaninND3.3 (0.0) f 12.2 (0.5) f 0.4NDNDNDNDND0.00.0NDND
  • a Abbreviations: ND, not done; Q/D, quinupristin-dalfopristin; SXT, trimethoprim-sulfamethoxazole; SE, S. epidermidis; MS, methicillin susceptible; MR, methicillin resistant; BSI, bloodstream-related infection; cSSSI, complicated skin and skin structure infection; PJI, prosthetic joint infection.

  • b Besides those for other and unidentified CoNS species, mainly S. epidermidis (n = 953), S. haemolyticus (n = 114), S. hominis (n = 176), S. lugdunensis (n = 25), S. saprophyticus (n = 30), S. warneri (n = 36), and S. xylosus (n = 24) data have been included. Only EUCAST interpretative criteria-based data are given; for CLSI criteria-based data, see the relevant publication.

  • c Data are shown for three collection periods, as follows: 2005/2007/2009.

  • d Data are shown only for isolates characterized as most disseminated.

  • e For methicillin-susceptible CoNS, besides those for other and unidentified CoNS species (n = 188), mainly S. capitis (n = 15), S. epidermidis (n = 57), S. haemolyticus (n = 5), S. hominis (n = 6), and S. warneri (n = 5) data are shown; for methicillin-resistant CoNS, besides those for other and unidentified CoNS species (n = 330), mainly S. epidermidis (n = 102), S. haemolyticus (n = 5), S. hominis (n = 10), S. lugdunensis (n = 18), and S. saprophyticus (n = 6) data are shown.

  • f Percentages given in parentheses show prevalences according to CLSI interpretative criteria.