TABLE 2

Primary foci of infection in cohorts with S. aureus bacteremiaa

Region (reference)% of MRSA cases in cohort% of HCA cases in cohortNo. (%) of cases with focus of infection Total no. of cases
Infective endocarditisOsteoarticularSSTIPleuropulmonaryLine relatedNo focus/unknownOther
Central Australia (32)21.625.69 (7.2)20 (16)42 (34)11 (8.8)9 (7.2)30 (24)4 (3.2)125
Australia (59)24.879.1433 (6)956 (13)1,415 (20)519 (7.2)1,387 (19)1,100 (15)1,421 (20)7,231
Sydney, Australia (65)1009215 (3.8)37 (9.3)80 (20)52 (13)140 (35)40 (10)35 (8.8)399
Calgary, Canada (12)b 11.375.379 (5.5)227 (16)224 (16)220 (15) 586 (41)104 (7.2)1,440
Missouri, USA (64)10092.60 (0)0 (0)39 (24)0 (0)37 (23)70 (43)17 (10)163
New York, USA (61)10097.991 (14)72 (11)112 (17)55 (8.4)302 (46)0 (0)20 (3.1)652
Birmingham, UK (66)10099.56 (3.1)3 (1.5)37 (19)0 (0)73 (37)68 (35)8 (4.1)195
Italy (57)53.985.50 (0)0 (0)14 (9.3)7 (4.6)23 (15)104 (69)3 (2)151
Israel (56)42.810055 (4.4)71 (5.6)294 (23)144 (11)172 (14)298 (24)227 (18)1,261
Thailand (58)27.655.18 (11)9 (12)20 (27)16 (22)10 (14)0 (0)10 (14)73
South Korea (63)10095.19 (3.4)16 (6)35 (13)24 (9)132 (49)36 (13)16 (6)268
Japan (62)100NA0 (0)0 (0)17 (15)10 (8.7)27 (23)23 (20)38 (33)115
Multisite (60)11.7NA282 (8.3)456 (13)502 (15)178 (5.2)942 (28)641 (19)394 (12)3,395
Total 15,468
  • a The mean percentages of patients for each primary focus of infection from all the studies were as follows: 5% for infective endocarditis, 8% for osteoarticular, 19% for SSTI, 9% for pleuropulmonary, 26% for line related, 24% for no focus/unknown, and 11% for other foci. MRSA, methicillin-resistant S. aureus; HCA, health care associated; SSTI, skin and soft tissue infection.

  • b Line-related bacteremia was not reported in this study.