TABLE 3

Sensitivity of blood culture versus bone marrow culture for the diagnosis of enteric fever

Author(s) (reference)Yr publishedNo. of samples tested (blood and bone marrow culture)Blood culture Bone marrow culture
Vol (ml)Culture mediumCulture systemNo. (%) positiveVol (ml)Culture mediumCulture systemNo. (%) positive
Hirsowitz and Cassel (599)195128NAa Ox bile brothManual13 (46.4)NAOx bile brothManual18 (64.3)
Gilman et al. (228)1975622Supplemented peptone brothManual25 (40.3)NASupplemented peptone broth, Ruiz-CastanedaManual56 (90.3)
Guerra-Caceres et al. (229)19796015Trypticase soy broth, Ruiz-CastanedaManual26 (43.3)0.5–1.0Trypticase soy broth, Ruiz-CastanedaManual57 (95.0)
Benavente et al. (236)1984363Ox bile brothManual15 (41.7)0.5–1.0Ox bile brothManual27 (75.0)
Hoffman et al. (215)19841183Ox bile brothManual64 (54.2)0.5–0.8Ox bile brothManual101 (85.6)
Vallenas et al. (230)1985433Ox bile brothManual19 (44.2)0.5Ox bile brothManual36 (83.7)
Hoffman et al. (231)1986613Ox bile brothManual27/56 (48.2)NAOx bile brothManual56/61 (91.8)
Hoffman et al. (231)1986618Ox bile brothManual38/56 (67.9)NAOx bile brothManual56/61 (91.8)
Rubin et al. (209)1990298Ox bile brothManual14 (48.3)0.5–0.8Ox bile brothManual25 (86.2)
Akoh (233)1991312Thioglycolate brothManual11 (35.4)1.0–2.0Thioglycolate brothManual19 (61.3)
Dance et al. (600)19911715Brain heart infusion broth with sodium polyanethol sulfonateManual14 (82.4)0.5–1.0Brain heart infusion broth with sodium polyanethol sulfonateManual15 (88.2)
Farooqui et al. (232)1991885Brain heart infusion broth, thioglycolate brothManual58 (65.9)0.5–1.0Brain heart infusion broth, thioglycolate brothManual88 (100)
Chaicumpa et al. (292)1992523Ox bile brothManual22 (42.3)0.5–0.8Ox bile brothManual32 (61.5)
Gasem et al. (601)1995863Ox bile brothManual57 (66.3)1.0Ox bile brothManual70 (81.4)
Gasem et al. (601)19958610Ox bile brothManual58 (67.4)1.0Ox bile brothManual70 (81.4)
Gasem et al. (602)2002538–10Becton Dickinson Bactec/F mediumContinuously monitored43 (81.1)1.0–2.0Becton Dickinson Bactec/F mediumContinuously monitored53 (86.9)
Wain et al. (214)2008735Brain heart infusion broth, brain heart infusion broth with sodium polyanethol sulfonate, ox bile brothManual57 (78.1)1.0NAManual69 (94.5)
Wain et al. (214)20086815Brain heart infusion, brain heart infusion with sodium polyanethol sulfonate, ox bile brothManual59 (86.7)1.0NAManual61 (89.7)
  • NA, not available.