TABLE 1.

Genes involved in cell wall biosynthesis in S. aureusa

ORFGeneFunction
Core genes
    SACOL1066fmtAutolysis and methicillin resistance-related protein
    SACOL1777htrAPutative serine protease
    SACOL1897prsAPutative protein export protein
    SACOL1932sgtBTransglycosylase domain protein
    SACOL1943vraSSensor histidine kinase
    SACOL1944Conserved hypothetical protein
    SACOL1945Conserved hypothetical protein
    SACOL1956Conserved hypothetical protein
    SACOL2116murZUDP-N-Acetylglucosamine 1-carboxylvinyl transferase 2
    SACOL2302lytRTranscriptional regulator, putative
    SACOL2352tcaATeicoplanin resistance-associated protein
    SACOL2435Conserved hypothetical protein
    SACOL2436Conserved hypothetical protein
    SACOL2518Conserved hypothetical protein
    SACOL2571Conserved hypothetical protein
Additional genes
    SACOL0033mecAPenicillin binding protein 2A
    SACOL0636mvaK1Melavonate kinase
    SACOL0693tagAPutative teichoic acid biosynthesis protein
    SACOL0743bacABacitracin resistance protein
    SACOL1161murIGlutamate racemase
    SACOL1279uppsUndecaprenyl pyrophosphatase synthetase
    SACOL1396fmtCAutolysis and methicillin-resistant-related protein
    SACOL1490pbpBPenicillin binding protein 2
    SACOL2116murZUDP-N-Acetylglucosamineenolpyruvate transferase
    SACOL2540srtASortase A
    SACOL1194pbpAPenicillin binding protein 1
    SACOL1932sgtBMonofunctional glycosyltransferase
  • a Based on data from references 168, 329, and 361. ORF, open reading frame, based on the S. aureus COL locus tag (SACOL).