TABLE 3.

Enzyme kinetics

Enzyme classSourceKm (μM)Reference(s)
BenzylpenicillinAmpicillinCefazolinCephaloridineCefoxitinCefotaximeAztreonamImipenemb
CE. cloacae0.60.41,500700.0240.010.00120.0499, 100
C. freundii0.40.2600350.2500.0050.00140.08599, 100
E. coli K-124.43.54001700.6501.70.00120.899, 100
S. marcescens1.70.015402750.3120.0580.0699, 100, 148
P. aeruginosa1.70.5a200.050.20.0500.02699, 100
ACT-12.11.7430>2000.50.070.0120.3725
MIR-10.40.16a930.7540.0040.1525
CMY-112.2541100.0550.0150.010.0525
CMY-20.40.16a930.070.0012<0.003ND25
ATEM-215-20226802,1003,000204
B. licheniformis7614312135205204
DOXA-29101630128210NH96
  • a Biphasic kinetics.

  • b ND, not determined; NH, no hydrolysis detected.