TABLE 2.

Genetic knockout of ampD homologue genes and ampC expression in P. aeruginosa PAO1a

StrainAvg level of ampC expression ± SDb
BasalInduced
PAO11c43 ± 9
PAΔD60 ± 19152 ± 38
PAΔDh21c48 ± 15
PAΔDh31c55 ± 5
PAΔDh2Dh32 ± 0.1481 ± 26
PAΔDDh262 ± 9234 ± 58
PAΔDDh3191 ± 521,014 ± 297
PAΔDDh2Dh31,020 ± 871,105 ± 88
  • a Modified from reference 91 with permission.

  • b Real-time reverse transcription-PCR was used to measure ampC expression in P. aeruginosa grown in the presence of 50 μg/ml of cefoxitin (induced) or the absence of cefoxitin (basal).

  • c Actual ampC expression data were not presented in the original report (91). Based on the methodology described and interpretation of the data presented, basal ampC expression was set to a value of 1 in this table.