TABLE 3.

Comparison of EUCAST, CLSI, and BSAC breakpoints for various antibiotics versus Acinetobacter spp.

AntibioticBreakpoints for susceptibility/resistance (μg/ml)
EUCASTaCLSIbBSACa
Imipenem, meropenem2/84/162/8
Ciprofloxacin1/11/41/1
Levofloxacin1/22/8
Amikacin8/1616/64
Gentamicin, tobramycin4/44/164/4
Netilmicin4/48/32
Ampicillin-sulbactam8/32
Piperacillin-tazobactam16/12816/16
Ticarcillin-clavulanate16/128
Ceftazidime, cefepime8/32
Ceftriaxone, cefotaxime8/64
Polymyxin B, colistin2/4
Trimethoprim-sulfamethoxazole2/4
Doxycycline, minocycline, tetracycline4/16
Tigecycline1/2
  • a For EUCAST and BSAC breakpoints, susceptibility is defined by a MIC equal to or lower than the first number and resistance is defined by a MIC greater than the second number.

  • b For CLSI breakpoints, susceptibility is defined by a MIC equal to or lower than the first number and resistance is defined by a MIC equal to or greater than the second number.