TABLE 2.

Clinical classification of infections caused by Scedosporium spp. and selected examples of other mycoses

Host-pathogen interactionLocalizationConventional mycological examplesPseudallescheria/Scedosporium
ColonizationAirways Candida spp.Probably transient; if persistent, suggests abnormal airways
Saprobic involvement of airwaysAbnormal airways (chronic sinusitis; preexisting cavitary lesions, i.e., pulmonary tuberculosis, pulmonary sarcoidosis)Aspergilloma, bronchiectatic involvement of Aspergillus, otomycosis, chronic Aspergillus sinusitisFungal balls (pseudallescherioma/scedosporioma, bronchiectatic involvement of P. boydii/ Scedosporium spp.)
InfectionSuperficial Malassezia spp.Not available
CutaneousDermatophytesDermal infections (nodules)/sporotrichoid
    Primary
    Secondary Fusarium solani (hematogenous)Secondary disseminationa
SubcutaneousChromoblastomycosisMycetoma
Phaeomycotic cystsSubcutaneous nodules
SporotrichosisSporotrichoid-like presentation
Invasive
    LocalizedInvasive pulmonary aspergillosisInvasive visceral pseudallescheriasis/ scedosporiosis
    DisseminatedDisseminated aspergillosis, fusariosis, filamentous fungi
  • a Cutaneous lesions (papules, nodular) are well-recognized manifestations of hematogenous dissemination of Scedosporium infection.