TABLE 4.

MIC distributions for H. influenzae and β-lactam resistance mechanismsa

Drug and strain typenMIC (μg/ml)
50%90%Range
Ampicillin
    BLNAS1550.250.50.031-0.5
    BLPAR (TEM-1)688162-64
    L-BLNAR189120.5-2
    BLNAR138241-16
    BLPACR-I5916322-64
    BLPACR-II12326416-64
Cefotaxime
    BLNAS0.00160.00310.004-0.063
    BLPAR (TEM-1)0.00160.00310.008-0.063
    L-BLNAR0.0630.1250.031-0.25
    BLNAR0.510.125-2
    BLPACR-I0.0630.1250.016-0.25
    BLPACR-II0.510.125-1
Meropenem
    BLNAS0.0310.0630.008-0.125
    BLPAR (TEM-1)0.0630.0630.031-0.063
    L-BLNAR0.1250.250.031-0.5
    BLNAR0.1250.250.031-0.5
    BLPACR-I0.1250.250.031-0.5
    BLPACR-II0.1250.250.063-0.25
  • a Data are from Hasegawa et al. (57). BLNAS, β-lactamase negative ampicillin susceptible; BLPAR, β-lactamase positive ampicillin resistant; L-BLNAR, low-level BLNAR; BLPACR-I, β-lactamase positive amoxicillin-clavulanate resistant (from L-BLNAR); BLPACR-II, β-lactamase positive amoxicillin-clavulanate resistant (from BLNAR).