TABLE 2.

Commercially available antibody assays for diagnosis of amebiasis

Antibody assaySensitivity, % (reference)Specificity, % (reference)Manufacturer
Cellognost-Amoebiasis (IHA)100a (134), 99 (84)90.9-100a (134), 99.8 (84)Dade Behring Marburg GmbH, Marburg, Germany
Novagnost Entamoeba IgG>95b>95bNovaTec Immundiagnostica GmbH, Dietzenbach, Germany
Bichro-Latex Amibe93.3 (194), 98.3 (149)95.5 (194), 96.1 (149)Fumouze Diagnostics, Levallois-Perret Cedex, France
I.H.A. Amoebiasis93.4 (149)97.5 (149)Fumouze Diagnostics, Levallois-Perret Cedex, France
Amoeba-Spot IFNAc (61)NA (61)bioMérieux, Marcy-l'Etoile, France
Amebiasis Serology microplate ELISA95b97bLight Diagnostics
Amebiasis Serology microwell EIA (HK-9 antigen, axenic)97.9 (84), 92.5 (169)94.8 (84), 91.3 (169)LMD Laboratories, Inc., Carlsbad, CA
RIDASCREEN Entamoeba (IgG detection)100b, 97.7-100 (100)95.6b, 97.4 (100)R-Biopharma AG, Darmstadt, Germany
  • a For the titer of ≥1:64, 100% sensitive and 90. 9% specific; for the titer of ≥1:512, 100% sensitive and 100% specific.

  • b As recommended by the manufacturer.

  • c NA, not available.