TABLE 1.

Characteristics of selected Helicobacter species

SpeciesPrimary mammalian hostPathologyAnimal model
Gastric Helicobacter spp.
    H. pyloriHuman, primateGastritis, peptic ulcer disease, gastric adenocarcinoma, MALT lymphomaMouse, Mongolian gerbil, guinea pig, gnotobiotic piglet
    H. felisCat, dog, mouseGastritis in natural host; may cause peptic ulcers or gastric adenocarcinoma in mouseMouse
    H. mustelaeFerretGastritis, peptic ulcer disease, gastric adenocarcinoma, MALT lymphomaNone
    H. acinonychisCheetah, tiger, other big catsGastritis, peptic ulcer diseaseMouse
    H. heilmanniiHuman, dog, cat, monkey, cheetah, ratGastritis, dyspeptic symptoms, MALT lymphomaMouse
Enterohepatic Helicobacter spp.
    H. hepaticusMouse, other rodentsProliferative typhlocolitis, hepatitis, hepatocellular carcinomaNone