TABLE 2.

Susceptibility to antibiotics of E. coli lacking an efflux pump

E. coli strain or characteristicMIC (μg/ml)a
CIPCHLTETCO-TRIM
CLSI recommended breakpoint concn432164/16
BSAC recommended breakpoint concn81624
Wild-type strain W31100.01581>32
tolC::kan0.002510.121
acrAB::kan0.002510.1216
acrD::kan0.01581>32
acrEF::kan0.002511>32
  • a CIP, ciprofloxacin; CHL, chloramphenicol; TET, tetracycline; CO-TRIM, cotrimoxazole. Data extracted from Sulavik et al. (215). (Note that values have been rounded to typical doubling dilutions for ease of comparison between tables.)