TABLE 8.

Susceptibility to antimicrobial agents of S. pneumoniae lacking or overexpressing pmrA

S. pneumoniae strain or characteristicMIC (μg/ml)a
NORNOR + RCIPPENEtBrACR
CLSI recommended breakpoint concn2
BSAC recommended breakpoint concn40.12
R6 (wild type)220.524
R6Nb16421616
R6N::cat220.524
  • a NOR, norfloxacin; R, reserpine; CIP, ciprofloxacin; EtBr, ethidium bromide; ACR, acriflavine. Data extracted from Gill et al. (55).

  • b Strain R6N overexpresses pmrA (163).