Infection control interventions appropriate to controlling spread of ESBL-producing organisms within a hospital

Identify patients infected with ESBL-producing organisms by use of appropriate detection methods in the clinical microbiology laboratory
Identify colonized patients by use of rectal swabs plated onto selective media
Perform molecular epidemiologic analysis of strains from infected or colonized patients (for example, by use of pulsed-field gel electrophoresis)
Institute contact isolation precautions, particularly if clonal spread is demonstrated
Institute controls on antibiotic use, particularly if numerous strain types are demonstrated