TABLE 5.

Percentage of DTaP- and DTP-vaccinated infants reported to have local or systemic reactions within 3 days of immunizationa

Category% of infants with reaction to:
DTaPbDTPc
Systemic
    Fever (temp > 100°F)
        First dose4.227.3
        Second dose11.334.1
        Third dose15.837.7
    Antipyretic use
        First dose39.360.5
        Second dose36.759.8
        Third dose36.361.4
    Fussiness
        First dose6.620.6
        Second dose7.723.5
        Third dose6.717.3
    Drowsy
        First dose29.943.5
        Second dose17.631.0
        Third dose12.924.6
    Anorexia
        First dose9.319.5
        Second dose8.916.5
        Third dose8.914.3
    Vomiting
        First dose6.37.0
        Second dose4.54.5
        Third dose4.25.3
Local (injection site)
    Redness
        First dose13.549.4
        Second dose17.147.7
        Third dose21.547.6
    Swelling
        First dose8.739.7
        Second dose12.134.1
        Third dose13.335.7
    Pain
        First dose3.827.3
        Second dose2.018.7
        Third dose2.115.8
  • a Data from reference 198.

  • b Thirteen candidate DTaP vaccines.

  • c Tri-Immunol (Lederle DTP).