TABLE 5.

Comparison of C. albicans, C. parapsilosis, and C. glabrata sepsisa

CharacteristicResults for:P value
C. albicansC. parapsilosisC. glabrata
Baseline characteristics
    No. of patients4189
    Gestational age (wk)26.6 ± 0.527.3 ± 1.329.7 ± 1.20.01
    Birth wt (g) 932 ± 75 965 ± 1941,442 ± 2920.02
    No. (%) of VLBW (<1,500 g) infants38 (93)7 (88)7 (78)NS
    No. (%) born via vaginal delivery26 (63)4 (50)7 (78)NS
Factors present at the diagnosis of fungemia
    Age at diagnosis (days)17 (11-31)25 (17-87)14 (10-21)NS
    No. (%) on antibiotics12 (38)3 (38)6 (67)NS
    No. (%) with apnea28 (68)4 (50)2 (22)0.01
    Lowest platelet count (103/mm3) 74 ± 9 39 ± 2 124 ± 340.04
    No. of positive blood cultures for fungus2.1 ± 1.11.8 ± 0.712.0 ± 1.3NS
    No. (%) with candiduria15 (37)2 (25)2 (22)NS
    No. (%) with meningitis5 (12)1 (13)1 (11)NS
    No. with renal abscessc/total no. tested (%)5/38 (13)1/7 (14)0/7 (0)NS
    No. with cardiac vegetations/total no. tested (%)2/30 (7)0/6 (0)0/8 (0)NS
    No. (%) with necrotizing enterocolitis6 (15)01 (11)NS
    No. (%) dying of Candida infection000NS
    No. (%) who died, all-cause mortality3 (7)00NS
  • a Data from reference 131. Plus-minus values are mean ± standard deviation. Median is given as 25th to 75th percentile.

  • b Significant difference between glabrata and non-glabrata groups (P < 0.05). NS, not significant.

  • c Urinary tract ultrasound and echocardiogram were not performed on every patient.