TABLE 2.

Organisms and death rates associated with bloodstream infections in VLBW (<1,500 g) neonatesa

OrganismEONSLONS
No. of infections (% of total)Mortality (%)bNo. of infections (% of total)Mortality (%)b
Gram-positive bacteria (total)31 (36.9)26922 (70.2)11.2
    GBS9 (10.7)30 (2.3)21.9
    Viridans streptococcus3 (3.6)
    Other streptococci4 (4.8)
    Listeria monocytogenes2 (2.4)
    Coagulase-negative Staphylococcus9 (10.7)629 (47.9)9.1
    Staphylococcus aureus1 (1.2)103 (7.8)17.2
    Enterococcus species43 (3.3)
    Other3 (3.6)117 (8.9)
Gram-negative bacteria (total)51 (60.7)41231 (17.6)36.2
    Escherichia coli37 (44.0)64 (4.9)34.0
    Haemophilus influenzae7 (8.3)
    Citrobacter2 (2.4)
    Bacteroides2 (2.4)
    Klebsiella1 (1.2)52 (4.0)22.6
    Pseudomonas35 (2.7)74.4
    Enterobacter33 (2.5)26.8
    Serratia29 (2.2)35.9
    Other2 (2.4)18 (1.4)
Fungi (total)2 (2.4)160 (12.2)31.8
    Candida albicans2 (2.4)76 (5.8)43.9
    Candida parapsilosis54 (4.1)15.9
    Other30 (2.3)
  • a NICHD Neonatal Network Survey, 1998 to 2000 (453, 454). A total of 5,447 patients with EONS and 6,215 patients with LONS were studied. There were a total of 84 bloodstream infections in the EONS patients (1.5% of the total) and 1,313 bloodstream infections in the LONS patients (21.1% of the total).

  • b All-cause mortality.