TABLE 6.

Criteria used for the identification of the triggering bacterium as a probable or possible cause of ReAa

BacteriumCriterion
Chlamydia 1. Probable ReA
    Chlamydia positive in urogenital smear plus symptomatic urethritis
    IgG ≥ 1/64 plus positive IgA or IgM plus Chlamydia positive in urogenital smear or symptomatic urethritis
    Antibody titers of 2 standard deviations (SD) above normal for IgG plus IgA or IgM plus symptomatic enteritis or Widal agglutination ≥ 1/320 (normal <1/60)
2. Possible ReA
    Chlamydia positive in urogenital smear or IgG ≥ 1/64 plus positive IgA or IgM
Yersinia 1. Probable ReA
    Yersinia-positive stool culture
    Antibody titers of 3 SD above normal for IgG plus IgA or IgM
    Antibody titers of 2 SD above normal for IgG plus IgA or IgM plus symptomatic enteritis
2. Possible ReA
    Antibody titers of 2 SD above normal for IgG plus IgA or IgM or Widal agglutination > 1/320 (normal, <1/160)
Salmonella 1. Probable ReA
    Salmonella-positive stool culture
    Antibody titers of 3 SD above normal for IgG plus IgA or IgM
    Antibody titers of 2 SD above normal for IgG plus IgA or IgM plus symptomatic enteritis
2. Possible ReA
    Antibody titers of 2 SD above normal for IgG plus IgA or IgM
Campylobacter 1. Probable ReA
    Campylobacter-positive stool culture
    Antibody titers of 3 SD above normal for IgG plus IgA or IgM
2. Possible ReA
    Antibody titers of 2 SD above normal for IgG plus IgA or IgM
  • a Always in the presence of an arthritis either asymmetrically or predominantly of the legs. For probable ReA, only one of the criteria has to be fulfilled. Data are from references 50, 71, 107, and 113.