TABLE 2.

Rapidity of Ad5-A24 induction of protection in swine

VaccineDay of challengeaViremiabProtectioncScored
PBSe1460/615.8
Ad5-A24f704/40
1404/40
4204/40
  • a The animals were challenged on the day indicated by direct inoculation in the heel bulb of the rear foot with 105 50% bovine infectious doses of virulent A24.

  • b Determined by virus isolation (number of positive animals).

  • c Number of animals protected/total number of animals.

  • d The score is the number of digits and snout with lesions; the maximum score is 17.

  • e PBS, phosphate-buffered saline.

  • f Animals were inoculated i.m. with 5 × 109 PFU.