TABLE 5.

P. falciparum CQ treatment failure in vivo for selected countries in South America, 1996 to 2002

RegionCountryNo. of data points identifiedPeriodAge range (yr)Outcome classificationPeriod of follow-up (days)Median %CQ-PF (range)aMedian %CQ-TTF (range)aSource or reference
South America/CaribbeanColombia319981-65WHO14, 2850 (44-56)44 (25-61)37, 156
Guyana11998>5Day 7, 14, and 28 cumulative parasite failure2833, 48, 5616
Venezuela11999AllWHO, 14, 28281001
Venezuela2199914-60WHO, 14, 282834 (20-47)35
  • a CQ-PF, CQ parasitologic failure (either R1-R3 or cumulative parasite failure); CQ-TTF, CQ clinical failure (either ETF + LTF or cumulative clinical failure).