TABLE 4.

Brucella antigens that induce a T-cell response

AntigenFunctionSpeciesHostProtectionReference(s)
P39Periplasmic binding protein B. melitensis Guinea pig, cattle, mouseYes, with CpG 3, 45, 46
BacterioferritinIron-binding protein B. melitensis Guinea pig, cattle, mouseYes, with CpG 3, 46
GroELHeat shock protein B. abortus Mouse, guinea pigNDa 117, 118, 120, 150
GroESHeat shock protein B. abortus Mouse, guinea pigND 117, 120
YajCTransmembrane protein B. abortus MouseND 158
UvrADNA repair enzyme B. abortus Cattle, mouse, guinea pigND 117, 120, 172
L7/L12Ribosomal proteins B. abortus MouseYes, with Freund's adjuvant 117, 120
BA14KUnknown B. abortus MouseND 34
SOD (BCSP20)Cu-Zn SOD B. abortus Cattle, mouseYes, but synthetic peptide 21, 152, 153
31 kDaUnknown B. abortus CattleND 25
  • a ND, not determined; CpG, unmethylated synthetic CpG oligonucleotides.