TABLE 2.

Detection of C. pneumoniae in atheromatous tissue specimens

StudyYrNo. of specimensType of tissueaResults [no. positive/total no. (%)] for:No. analyzed by two Cpn testcNo. positive by two Cpn testc
ICC genus antibodyICC species antibodyPCRCultureEMISH
Shor et al. (128)19927Coronary5/7 (71%)5/7 (71%)NDbND7/7 (100%)ND00
Kuo et al. (71)199336Coronary15/36 (42%)15/36 (42%)13/30 (43%)0/36 (0%)6/21 (29%)ND308
Kuo et al. (72)199321Aorta7/21 (33%)7/21 (33%)NDNDNDND00
Kuo et al. (73)199518Coronary7/18 (39%)5/18 (28%)3/18 (17%)NDNDND182
Campbell et al. (17)199538Coronary17/38 (45%)17/38 (45%)12/38 (32%)ND2/2 (100%)ND389
Grayston et al. (43)199561Carotid36/61 (59%)10/10 (100%)8/30 (27%)0/4 (0%)NDND(10)(6)
Ong et al. (102)199643ArteriesND3/12 (25%)19/43 (44%)NDNDND123
Weiss et al. (144)199680CoronaryNDND1/56 (2%)0/58 (0%)0/22 (0%)ND560
Muhlestein et al. (94)199690Coronary71/90 (79%)NDNDND3/5 (60%)ND00
Blasi et al. (9)199651AortaNDND26/51 (51%)NDNDND00
Ramirez et al. (113)199610Coronary5/10 (50%)5/10 (50%)5/10 (50%)1/10 (10%)3/10 (30%)1/10 (10%)105
Juvonen et al. (65)199712Aorta12/12 (100%)8/12 (67%)6/6 (100%)0/3 (0%)3/4 (75%)ND66
Juvonen et al. (66)199717AVS15/17 (88%)9/17 (53%)3/17 (18%)ND2/3 (67%)ND171
Jackson et al. (58)199757Coronary11/57 (19%)8/57 (14%)9/57 (16%)NDNDND571
Jackson et al. (59)199725Carotid8/16 (50%)ND6/25 (24%)1/25 (4%)NDND250
Kuo et al. (74)199739Periph8/20 (40%)ND5/39 (13%)0/26 (0%)NDND260
Maass et al. (82)199761CarotidNDND9/61 (15%)NDNDND00
Chiu et al. (19)199776Carotid30/76 (39%)41/76 (54%)NDNDNDND00
Nyström-Rosander et al. (100)199739AVSNDND19/39 (49%)ND1/1 (100%)ND01
Maass et al. (83)199870CoronaryNDND21/70 (30%)11/70 (16%)NDND011
Yamashita et al. (151)199820Carotid11/20 (55%)11/20 (55%)NDNDNDND00
Petersen et al. (112)199840AortaNDND14/40 (35%)NDNDND00
Lindholt et al. (80)1998124AortaNDND0/124 (0%)NDNDND00
Paterson et al. (107)199849Carotid/coronaryNDND0/49 (0%)NDNDND00
Shor et al. (129)199835Various3/7 (43%)ND15/35 (43%)ND11/22 (50%)ND00
Taylor-Robinson et al. (133)1998117VariousNDND17/117 (15%)NDNDND00
Davidson et al. (25)199860Carotid20/60 (33%)2/3 (67%)14/60 (23%)NDNDND(3)(2)
Andreasen et al. (3)199823AVSNDND0/23 (0%)NDNDND00
Ouchi et al. (104)199851Coronary/iliac18/50 (36%)18/50 (36%)20/51 (39%)0/24 (0%)NDND5012
Maass et al. (84)1998158CoronaryNDND34/158 (22%)NDNDND00
Maass et al. (85)1998238ArteriesNDND51/238 (21%)NDNDND00
Wong et al. (147)199968Artery/veinNDND26/68 (38%)NDNDND00
Bartels et al. (6)199938VeinNDND8/32 (25%)5/32 (16%)NDND325
Nadrchal et al. (97)199943Carotid/aortaNDND11/43 (26%)NDNDND00
Thomas et al. (138)1999187CoronaryNDND68/187 (36%)NDNDND00
Blasi et al. (32)199930CarotidNDND18/30 (60%)NDNDND00
Jantos et al. (64)199950CoronaryNDND4/50 (8%)NDND0/50 (0%)00
Bartels et al. (7)2000125Coronary/vein graftsNDND23/125 (18%)12/125 (10%)NDND12512
Apfalter et al. (4)200038VariousNDNDND3/38 (8%)NDND00
Berger et al. (8)2000130VariousNDND33/130 (25%)NDNDND00
Gibbs et al. (38)200098CarotidNDND25/98 (26%)NDNDND00
Farsak et al. (33)200046VariousNDND12/46 (26%)NDNDND00
Ericson et al. (30)200060Coronary37/60 (62%)38/56 (68%)NDNDNDND00
No. analyzed2,6796764432,294451976050276
No. positive33620255833381
% positive49.7%45.6%24.32%7.32%39.18%1.67%15.14%
  • a AVS, aortic valve sclerosis.

  • b ND, not done.

  • b Parentheses indicate that the number of specimens analyzed was biased. The values in parentheses are numbers of samples that were prescreened and positive for an ICC genus antibody.