TABLE 3.

Detection of C. pneumoniae in normal tissue specimens

StudyYrControlsaNo. of specimensResults [no. positive/total no. (%)]No. analyzed by two Cpn testNo. positive by two Cpn test
ICC genus antibodyICC species antibodyPCRCultureEMISH
Shor et al. (128)1992Non-CAD50/5 (0%)0/5 (0%)NDNDNDND00
Kuo et al. (71)1993NSc110/11 (0%)0/11 (0%)0/6 (0%)NDNDND60
Kuo et al. (72)1993Aorta40/4 (0%)0/4 (0%)NDNDNDND00
Kuo et al. (73)1995Non-CAD310/31 (0%)ND0/31 (0%)NDNDND00
Grayston et al. (43)1995Non-ather130/13 (0%)NDNDNDNDND00
Ong et al. (102)1996Non-ather6NDND3/6 (50%)NDNDND00
Muhlestein et al. (94)1996Non-ather241/24 (4%)NDNDNDNDND00
Blasi et al. (9)1996Normal51NDND0NDNDND00
Ramirez et al. (113)1996Non-ather20/2 (0%)ND0/2 (0%)0/2 (0%)0/2 (0%)0/2 (0%)20
Juvonen et al. (65)1997Non-ather120/12 (0%)0/12 (0%)0/12 (0%)NDNDND120
Juvonen et al. (66)1997AV18ND9/18 (50%)NDNDNDND00
Jackson et al. (58)1997Tissue1469/146 (6%)3/8 (38%)5/146 (3%)NDNDND80
Kuo et al. (74)1997Normal80/8 (0%)ND0/8 (0%)NDNDND00
Maass et al. (82)1997Non-ather39NDND0/39 (0%)NDNDND00
Chiu et al. (19)1997Normal200/20 (0%)0/20 (0%)NDNDNDND00
Nyström-Rosander et al. (100)1997AV11NDND1/11 (9%)ND0/1 (0%)ND00
Maass et al. (83)1998Non-ather17NDND0NDNDND00
Petersen et al. (112)1998Aorta40NDND2/40 (5%)NDNDND00
Ouchi et al. (104)1998Normal120/12 (0%)0/12 (0%)0/12 (0%)NDNDND120
Maass et al. (85)1998Normal17NDND0/17 (0%)NDNDND00
Wong et al. (147)1999Artery/vein71NDND12/71 (17%)NDNDND00
Bartels et al. (6)1999Vein20NDND1/20 (5%)0NDND200
Bartels et al. (7)2000Vein20NDND1/20 (5%)NDNDND00
Farsak et al. (33)2000Normal39NDND0/39 (0%)NDNDND00
No. analyzed637312905482232600
No. positive101225000
% positive3.21%13.33%4.56%0%0%0%0%
  • a AV, aortic valve; Non-ather, nonatherosclerotic specimen.

  • b ND, not done.

  • c NS, not stated.