TABLE 3.

Secreted factors implicated in the intestinal inflammatory response in IBD

ClassFactor
CytokinesIL-12, TNF, IFN-γ, IL-10, IL-18, IL-15, lymphotoxins alpha and beta, IL-1β
ChemokinesIL-8, MCP-1, ENA-78, RANTES
Growth factorsKeratinocyte growth factor, vascular endothelial growth factor, epidermal growth factors, trefoil factors
OtherMatrix metalloproteinases