TABLE 2.

Antimicrobial activity for the three most frequently isolated species of nonpigmented RGM

SpeciesAntimicrobial agenta
>90% susceptible or intermediate (% if <100%)<90% susceptible or intermediate (approx. % susceptibility/intermediate)
M. fortuitum groupAmikacin, cefoxitin,c ciprofloxacin, gatifloxacin, imipenem, levofloxacin, linezolid (96%),f sulfamethoxazole or trimethoprim-sulfamethoxazoleClarithromycin (80%),b doxycycline (46%),d vancomycin (38%)e
M. abscessusAmikacin (98%),d cefoxitin (95%),h clarithromycinbCiprofloxacin (<1%),g doxycycline (4%),d imipenem (57%),h linezolid (48%)
M. chelonaeAmikacin (97%), clarithromycin,b gatifloxacin (96%),i linezolid (94%),f tobramycinCiprofloxacin (19%),g doxycycline (26%),d imipenem (40%)h
  • a Data given in exact percentages are referenced in the publications in the footnotes; otherwise, approximate percent positive is given.

  • b Reference 20.

  • c Excludes M. fortuitum third biovar sorbitol positive (proposed M. houstonense), of which >90% are resistant (194).

  • d Reference 171.

  • e C. J. Crist, R. J. Wallace Jr., B. A. Brown-Elliott, and L. B. Mann, Abstr. 101st Gen. Meet. Am. Soc. Microbiol 2001, abstr. U-35, 2001.

  • f Reference 195.

  • g Reference 187.

  • h Reference 192.

  • i B. A. Brown-Elliott, R. J. Wallace Jr., and C. J. Crist, Program Abstr. 41st Intersci. Conf. Antimicrob. Agents Chemother., abstr. E-723, 2001.