Public health impact of congenital CMV infection in the United Statesa

ParameterEstimated value
No. of live births per year4,000,000
Rate of congenital CMV infection (average)1%
No. of infected infants40,000
No. of infants symptomatic at birth (5-7%)2,800
    No. with fatal disease (±12%)336
    No. with sequelae (90% of survivors)2,160
No. of infants asymptomatic at birth (93-95%)37,200
    No. with late sequelae (15%)5,580
Total no. with sequelae or fatal outcome8,076
  • a From Stagno (258), used with permission.