Table 1.

Known immunogenic proteins of M. paratuberculosis

M. paratuberculosis proteinCharacteristicSize (kDa)Reference(s)
GroESHeat shock protein10 60
AhpDAlkyl hydroperoxide reductase D19 222
32-kDa antigenFibronectin binding properties, secreted protein32 100
34-kDa antigenCell wall antigen, B-cell epitope34 62, 87, 88, 127, 264
34-kDa antigenSerine protease34 33
34.5-kDa antigenCytoplasmic protein,M. paratuberculosis species specific34.5 214
35-kDa antigenImmunodominant protein35 102
42-kDa antigenCytoplasmic M. paratuberculosis-specific protein42 320
44.3-kDa antigenSoluble protein44.3 214
AhpCAlkyl hydroperoxide reductase C45 222
65-kDa antigenGroEL heat shock protein65 100, 101