Table 5.

Characteristics of novel, unrelated ESBLs

β-LactamaseClosest relative pI Preferred substrateaCountry of origin Bacterial species Reference
BES-1Penicllinase from Yersinia enterocolitica7.5 CTX, CAZ, ATMBrazilS. marcescens20
FEC-1 8.2 CTX Japan E. coli93
GES-1 Penicillinase from P. mirabilis5.8 CAZ French Guiana K. pneumoniae136
CME-1 VEB-1 >9.0 CAZIsolated from reference strain Chryseobacterium meningosepticum147
PER-1 PER-2 5.4 CAZFrance P. aeruginosa113
PER-2 PER-15.4 CAZ Argentina S. enterica serovar Typhimurium 14
SFO-1 AmpA from S. fonticola7.3 CTX Japan E. cloacae94
TLA-1CME-1 9.0 CAZ, CTX, ATM Mexico E. coli153
VEB-1 PER-1, PER-2 5.35 CAZ, ATMVietnam/Thailand E. coli135
  • a CTX, cefotaxime; CAZ, ceftazidime; ATM, aztreonam.