Table 13.

Characteristics of the reported cases of laboratory-acquired infection with Plasmodiumspp.a

CharacteristicNo. (%) of cases (n = 34)
Species
P. falciparum 15 (44.1)
P. cynomolgi 10 (29.4)
P. vivax 9 (26.5)
Decade of occurrence (if known) or publication
 1920s1 (2.9)
 1930s0
 1940s0
 1950s4 (11.8)
 1960s7 (20.6)
 1970s8 (23.5)
 1980s9 (26.5)
 1990s4 (11.8)
 Unknown1 (2.9)
Country or region of occurrence
 United States20 (58.8)
 Europe12 (35.3)
 New Zealand1 (2.9)
 Asia1 (2.9)
Route of exposure
 Vector-borne transmission19 (55.9)
 Parenteral10 (29.4)
 Nonintact skin5 (14.7)
Clinical manifestations
 Symptomatic cases34 (100)
 Severe cases2 (5.9)b
 Fatal cases0
  • a The median incubation period was 12.5 days (range, 4 to 17 days) for all infections due to non-vector-related exposures (14 cases with available data), 12 days (range, 7 to 17 days) for the subset of infections due to parenteral exposures (n = 9), and 13 days (range, 4 to 17 days) for the subset of infections due to exposures via nonintact skin (n = 5) .

  • b Two persons infected with P. falciparum developed manifestations suggestive of cerebral malaria.