Table 5.

Antibody and antigen detection tests availablea in the United States for parasitic infectionsb

DiseaseAntibody test(s)cAntigen test(s)c,d
AmebiasisEIAEIA, Rapidd
BabesiosisIFA, IB
Chagas' diseaseEIA, IFA
CryptosporidiosisEIA, DFA, IFA, Rapidd
CysticercosisEIA, IB
EchinococcosisEIA, IB
FascioliasisEIA
FilariasisEIAEIA, Rapid
GiardiasisEIA, DFA, IFA, Rapidd
LeishmaniasisIFA, EIA
MalariaIFARapid
SchistosomiasisEIA, IB
StrongyloidiasisEIA
ToxoplasmosisEIA, IFA
TrichinellosisBF, EIA
  • a The word “available” signifies availability of the test through commercial laboratories or at reference laboratories (e.g., at the CDC). The list is not all-inclusive; additional tests (e.g., radioimmunoprecipitation assay for antibody to Trypanosoma cruzi) may be available through research laboratories. Inclusion of a test in the list does not imply that it is endorsed by CDC or that it has been well evaluated.

  • b This table is adapted from reference175 with permission from the publisher. If possible, serum specimens that may be tested repeatedly (e.g., preemployment specimens, which are useful for comparison with post-accident specimens) should be divided into aliquots to minimize repeated freezing and thawing of individual specimens, which could negatively influence the outcome of some serologic tests.

  • c Some of the antibody tests and all of the antigen tests are available as commercial kits. Abbreviations, in alphabetical order: BF, bentonite flocculation; DFA, direct fluorescent-antibody assay; EIA, enzyme immunoassay; IB, immunoblot; IFA, indirect fluorescent-antibody assay; IHA, indirect hemagglutination; LA, latex agglutination; Rapid, rapid immunochromatographic diagnostic test.

  • d The antigen tests listed for amebiasis, cryptosporidiosis, and giardiasis detect antigen in stool.