Table 6.

Compounds with anti-HIV activity

TargetCompoundClassPlantReference(s)
Reverse transcriptaseEllagitanninTannina 155
Hydroxymaprounic acid, hydroxybenzoateTerpenoids Maprounea africana 173
Betulinic acid, platanic acidTerpenoids Syzigium claviflorum 74
CatechinPolyphenol 147
Faicalein, quercetin, myricetin, baicalinFlavonoids Quercus rubra, others 165, 208, 216
Nigranoic acidTerpenoids Schisandra sphaerandra 212
Amentoflavone, scutellarein, othersFlavonoids, flavones 96, 146,164, 165, 208, 217, 218
BenzophenanthridineAlkaloid 200,217
ProtoberberineAlkaloid 217
PsychotrinesAlkaloidsIpecac (Cephaelis ipecacuanha) 217
Michellamine BAlkaloid Ancistrocladus korupensis 142
SuksdorfinCoumarins Lomatium suksdorfii 126
CoriandrinCoumarinCoriander (Coriandrum sativum) 99
Caffeic acidTannin Hyssop officinalis 119
Cornusin, othersCondensed and hydrolyzable tannins Cornus officinalis and others 111
SwertifranchesideFlavonoid Swertia franchetiana 172
Salaspermic acidFlavonoid Trypterygium wilfordii 40
GlycyrrhizinFlavonoidLicorice (Glycyrrhiza rhiza) 102, 242
ProteinCactus (Opuntia streptacantha) 3
Methyl nordihydroguaiaretic acidLignanMany trees 80
Thuja polysaccharidePolysaccharide Thuja occidentalis 160
Lignin-polysaccharide complexesJapanese white pine (Pinus parvifloria) 126
IntegraseFlavonoids, flavones 32, 67
MAP30, GAP31, DAP 32, DAP 30Proteins Momordica charantia,Gelonium multiflorum 97, 128-130
Lectins 20
Caffeic acidTerpenoid 68
CurcuminTerpenoidTurmeric (Curcuma longa) 139
QuercetinFlavonoid Quercus rubra 67
ProteaseCarnosolic acidTerpenoidRosemary (Rosmarinus officinalis) 171
Ursolic acidTerpenoids Geum japonicum 246
Flavonoids, flavones 32, 48, 67
AdsorptionMannose-specific lectinsLectinsSnowdrop (Galanthus), daffodil (Narcissus), amaryllis (Amaryllis),Gerardia 148
Schumannificine 1Alkaloid Schumanniophyton magnificum 94
PrunellinPolysaccharide Prunella 249
Viral fusionMannose- andN-acetylglucosamine-specific lectinsLectins Cymbidium hybrid,Epiactic helleborine, Listeria ovata,Urtica dioica 20
Syncytium formationPropolisMixtureVarious trees 9,52
Michellamine BAlkaloid Ancistrocladus korupensis 142
MAR-10Polysaccharide Hyssop officinalis 81
Interference with cellular factorsChrysinFlavone Chrysanthemum morifolium 48
29,000-mol-wt proteinProteinPokeweed (Phytolacca) 41
HypericinAnthraquinoneSt. John’s wort (Hypericum) 41, 99
CamptothecinAlkaloid? 169
Trichosanthin, momorcharinsRibosome-inactiving proteinsCucurbitaceae family 141
UnknownSulfated polysaccharide Prunella vulgaris 214
Sulfonated polysaccharide Viola yedoensis 154
JacalinLectin? 46, 64
Zingibroside R-1Terpenoid Panax zingiberensisWu et Feng 86
ThiarubrinesTerpenoidsAsteraceae 98
ChrysinFlavonoid Chrysanthemum morifolium 96
Essential oil/terpenoids Houttuynia cordata 88
  • a —, unspecified.