Table 4.

Oral and selected topical azole antifungal agents for superficial mycoses

Clinical useOralaOral/topicalaTopical onlya
ITRAFLUCKETOCLOTECONMICOOXICTERCbTIOCb
Mucocutaneous candidiasis
 Oropharyngealc d e
 Esophagealc d
 Vaginal/genitalg d g g h h
 Cutaneousf
 Chronicf
Onychomycosis
 Candida√ (T)a
 Dermatophytesf,h
Dermatophytoses
 Tinea corporis/cruris
 Tinea pedisf f
 Tinea capitis/barbaef f
 Pityriasis (tinea) versicolorf f
  • a ITRA, itraconazole; FLUC, fluconazole; KETO, ketoconazole; CLOT, clotrimazole; ECON, econazole; MICO, miconazole; OXIC, oxiconazole; TERC, terconazole; TIOC, tioconazole; (T), topical only.

  • b For vaginal use only.

  • c Oral solution.

  • d Second-line azole.

  • e Troches.

  • f Promising.

  • g CDC-recommended regimen.

  • h Nail lacquer.