TABLE 2

IS and composite transposons associated with resistance genes in staphylococci and enterococci

ISaTnDeterminantAssociated resistance(s)Hostb
IS16Tn1547vanB1VancomycinE
IS256cfrPhenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin AS
Tn1547vanB1VancomycinE
Tn4001aacA-aphDGentamicin/kanamycin/tobramycinS
Tn5281aacA-aphDGentamicin/kanamycin/tobramycinE
Tn5384aacA-aphDGentamicin/kanamycin/tobramycinE
Tn5384erm(B)MLS antibioticsE
IS257caadDKanamycin/neomycin/paromomycin/tobramycinS
aphA-3Kanamycin/neomycinS
bcrABBacitracinS
bleBleomycinS
dfrKTrimethoprimS
erm(C)MLS antibioticsS
fosB5FosfomycinS
fusBFusidic acidS
ileS2 (mupA)MupirocinS
qacCAntiseptics/disinfectantsS
sat4StreptothricinS
tet(K)TetracyclineS
tet(L)TetracyclineS
vat(A)Streptogramin AS
vga(A)Streptogramin A/pleuromutilins/lincosamidesS
vgb(A)Streptogramin BS
Tn924aacA-aphDGentamicin/kanamycin/tobramycinE
Tn4003dfrATrimethoprimS
Tn6072aacA-aphDGentamicin/kanamycin/tobramycinS
Tn6072spcSpectinomycinS
IS1182Tn5405aadEStreptomycinS, E
Tn5405aphA-3Kanamycin/neomycinS, E
Tn5405sat4StreptothricinS, E
IS1216cfrPhenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin AE
strStreptomycinE
Tn5385aacA-aphDGentamicin/kanamycin/tobramycinE
Tn5385aadEStreptomycinE
Tn5385blaZPenicillinsE
Tn5385erm(B)MLS antibioticsE
Tn5385tet(M)Tetracycline/minocyclineE
Tn5482vanAVancomycinE
Tn5506vanAVancomycinE
IS1272TnSha1fabITriclosanS
TnSha2fabITriclosanS
IS21-558cfrPhenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin AS
lsa(B)LincosamidesS
ISEnfa4cfrPhenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin AS, E
ISSau10aadDKanamycin/neomycin/paromomycin/tobramycinS
dfrKTrimethoprimS
erm(C)MLS antibiotics
erm(T)MLS antibioticsS
tet(L)TetracyclineS
  • a Information is available from references cited in the text as well as from other references (16, 412, 494507).

  • b S, Staphylococcus; E, Enterococcus.

  • c IS257 is also known as IS431.